Tumor-derived IL-6 and trans-signaling among tumor, fat, and muscle mediate pancreatic cancer cachexia JE Rupert, A Narasimhan, DHA Jengelley, Y Jiang, J Liu, E Au, ... Journal of Experimental Medicine 218 (6), e20190450, 2021 | 114 | 2021 |
A graph neural network model to estimate cell-wise metabolic flux using single cell RNA-seq data N Alghamdi, W Chang, P Dang, X Lu, C Wan, S Gampala, Z Huang, ... Genome Research, 2020.09. 23.310656, 2021 | 67 | 2021 |
LTMG: a novel statistical modeling of transcriptional expression states in single-cell RNA-Seq data C Wan, W Chang, Y Zhang, F Shah, X Lu, Y Zang, A Zhang, S Cao, ... Nucleic acids research 47 (18), e111-e111, 2019 | 52 | 2019 |
Sestrin 3 Protects Against Diet‐Induced Nonalcoholic Steatohepatitis in Mice Through Suppression of Transforming Growth Factor β Signal Transduction M Huang, HG Kim, X Zhong, C Dong, B Zhang, Z Fang, Y Zhang, X Lu, ... Hepatology 71 (1), 76-92, 2020 | 46 | 2020 |
Lysine-Specific Demethylase 1 Mediates AKT Activity and Promotes Epithelial-to-Mesenchymal Transition in PIK3CA-Mutant Colorectal Cancer SA Miller, RA Policastro, SS Savant, S Sriramkumar, N Ding, X Lu, ... Molecular Cancer Research 18 (2), 264-277, 2020 | 32 | 2020 |
Hyperglycemia cooperates with Tet2 heterozygosity to induce leukemia driven by proinflammatory cytokine–induced lncRNA Morrbid Z Cai, X Lu, C Zhang, S Nelanuthala, F Aguilera, A Hadley, B Ramdas, ... The Journal of Clinical Investigation 131 (1), 2021 | 29 | 2021 |
Transcription factor expression as a predictor of colon cancer prognosis: a machine learning practice J Liu, C Dong, G Jiang, X Lu, Y Liu, H Wu BMC medical genomics 13, 1-10, 2020 | 24 | 2020 |
Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: exploiting this novel finding as a potential target S Gampala, F Shah, X Lu, H Moon, O Babb, N Umesh Ganesh, ... Journal of Experimental & Clinical Cancer Research 40 (1), 251, 2021 | 23 | 2021 |
Astrocytes modulate neurodegenerative phenotypes associated with glaucoma in OPTN (E50K) human stem cell-derived retinal ganglion cells C Gomes, KB VanderWall, Y Pan, X Lu, SS Lavekar, KC Huang, ... Stem Cell Reports 17 (7), 1636-1649, 2022 | 19 | 2022 |
BATF Regulates T Regulatory Cell Functional Specification and Fitness of Triglyceride Metabolism in Restraining Allergic Responses C Xu, Y Fu, S Liu, J Trittipo, X Lu, R Qi, H Du, C Yan, C Zhang, J Wan, ... The Journal of Immunology 206 (9), 2088-2100, 2021 | 12 | 2021 |
PLUS: Predicting cancer metastasis potential based on positive and unlabeled learning J Zhou, X Lu, W Chang, C Wan, X Lu, C Zhang, S Cao PLOS Computational Biology 18 (3), e1009956, 2022 | 11 | 2022 |
Sesn3 protects against diet-induced nonalcoholic steatohepatitis in mice via suppression of the TGFβ signal transduction M Huang, HG Kim, X Zhong, C Dong, B Zhang, Z Fang, Y Zhang, X Lu, ... Hepatology (Baltimore, Md.) 71 (1), 76, 2020 | 7 | 2020 |
SSMD: a semi-supervised approach for a robust cell type identification and deconvolution of mouse transcriptomics data X Lu, SW Tu, W Chang, C Wan, J Wang, Y Zang, B Ramdas, R Kapur, ... Briefings in bioinformatics 22 (4), bbaa307, 2021 | 5 | 2021 |
ICTD: A semi-supervised cell type identification and deconvolution method for multi-omics data W Chang, C Wan, X Lu, S Tu, Y Sun, X Zhang, Y Zang, A Zhang, K Huang, ... BioRxiv, 2019 | 5 | 2019 |
Acid-base homeostasis and implications to the phenotypic behaviors of cancer Y Zhou, W Chang, X Lu, J Wang, C Zhang, Y Xu Genomics, Proteomics & Bioinformatics, 2022 | 3 | 2022 |
Prospective, placebo-controlled, randomized study of metformin for breast cancer prevention in overweight/obese women T Ballinger, N Marino, R German, J True, X Lu, S Cao, AM Storniolo, ... Cancer Research 80 (4 Supplement), P1-13-03-P1-13-03, 2020 | 2 | 2020 |
Pipeline for characterizing alternative mechanisms (PCAM) based on bi-clustering to study colorectal cancer heterogeneity S Cao, W Chang, C Wan, X Lu, P Dang, X Zhou, H Zhu, J Chen, B Li, ... Computational and Structural Biotechnology Journal 21, 2160-2171, 2023 | 1 | 2023 |
Tumor Infiltrating Lymphocytes in Multi-National Cohorts of Ductal Carcinoma In Situ (DCIS) of Breast SS Badve, S Cho, X Lu, S Cao, S Ghose, AA Thike, PH Tan, IT Ocal, ... Cancers 14 (16), 3916, 2022 | 1 | 2022 |
Cell‐type specific variations of within pathway interaction in AD using covariance regression X Lu, C Zhang, Y Zhao, S Cao Alzheimer's & Dementia 17, e057873, 2021 | 1 | 2021 |
Ref-1 redox function identified as mitochondrial metabolic regulator in pancreatic cancer cells but not in CAFs S Gampala, F Shah, X Lu, H Moon, GE Sandusky, E Hulsey, AL Mosley, ... Cancer Research 81 (5 Supplement), PO025-PO025, 2021 | 1 | 2021 |