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Daniel Zabala Alvarez
Daniel Zabala Alvarez
Principal Investigator Drug Discovery at FAES FARMA
Verified email at faes.es
Title
Cited by
Cited by
Year
Engineering precursor metabolite pools for increasing production of antitumor mithramycins in Streptomyces argillaceus
D Zabala, AF Braña, AB Flórez, JA Salas, C Méndez
Metabolic engineering 20, 187-197, 2013
872013
Identification by genome mining of a type I polyketide gene cluster from Streptomyces argillaceus involved in the biosynthesis of pyridine and piperidine alkaloids argimycins P
S Ye, B Molloy, AF Braña, D Zabala, C Olano, J Cortés, F Morís, JA Salas, ...
Frontiers in Microbiology 8, 235379, 2017
432017
Transcriptional regulation of mithramycin biosynthesis in Streptomyces argillaceus: dual role as activator and repressor of the PadR-like regulator MtrY
AB Florez, S Alvarez, D Zabala, AF Brana, JA Salas, C Mendez
Microbiology 161 (2), 272-284, 2015
282015
A Flavin-Dependent Decarboxylase–Dehydrogenase–Monooxygenase Assembles the Warhead of α, β-Epoxyketone Proteasome Inhibitors
D Zabala, JW Cartwright, DM Roberts, BJC Law, L Song, M Samborskyy, ...
Journal of the American Chemical Society 138 (13), 4342-4345, 2016
262016
Pentamycin Biosynthesis in Philippine Streptomyces sp. S816: Cytochrome P450-Catalyzed Installation of the C-14 Hydroxyl Group
S Zhou, L Song, J Masschelein, FAM Sumang, IA Papa, TO Zulaybar, ...
ACS Chemical Biology 14 (6), 1305-1309, 2019
212019
Increasing antibiotic production yields by favoring the biosynthesis of precursor metabolites glucose-1-phosphate and/or malonyl-CoA in Streptomyces producer strains
D Zabala, AF Braña, JA Salas, C Méndez
The Journal of antibiotics 69 (3), 179-182, 2016
212016
Heterologous reconstitution of the biosynthesis pathway for 4-demethyl-premithramycinone, the aglycon of antitumor polyketide mithramycin
D Zabala, L Song, Y Dashti, GL Challis, JA Salas, C Méndez
Microbial Cell Factories 19, 1-12, 2020
42020
Discovery and biosynthesis of persiathiacins: Unusual polyglycosylated thiopeptides active against multi-drug resistant tuberculosis
Y Dashti, F Mohammadipanah, M Belousoff, A Vocat, D Zabala, CD Fage, ...
bioRxiv, 2021.10. 24.465558, 2021
22021
Parallelized gene cluster editing illuminates mechanisms of epoxyketone proteasome inhibitor biosynthesis
C Huang, D Zabala, ELC De Los Santos, L Song, C Corre, LM Alkhalaf, ...
Nucleic Acids Research 51 (3), 1488-1499, 2023
12023
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