| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10685 | 2021 |
| Current review of genetics of human obesity: from molecular mechanisms to an evolutionary perspective D Albuquerque, E Stice, R Rodríguez-López, L Manco, C Nóbrega Molecular genetics and genomics 290, 1191-1221, 2015 | 309 | 2015 |
| The contribution of genetics and environment to obesity D Albuquerque, C Nóbrega, L Manco, C Padez British medical bulletin 123 (1), 159-173, 2017 | 296 | 2017 |
| Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic mice C Nóbrega, I Nascimento-Ferreira, I Onofre, D Albuquerque, H Hirai, ... PloS one 8 (1), e52396, 2013 | 137 | 2013 |
| Silencing ataxin-3 mitigates degeneration in a rat model of Machado–Joseph disease: no role for wild-type ataxin-3? S Alves, I Nascimento-Ferreira, N Dufour, R Hassig, G Auregan, ... Human molecular genetics 19 (12), 2380-2394, 2010 | 129 | 2010 |
| Machado–Joseph disease/spinocerebellar ataxia type 3: lessons from disease pathogenesis and clues into therapy CA Matos, LP de Almeida, C Nóbrega Journal of neurochemistry 148 (1), 8-28, 2019 | 119 | 2019 |
| Beclin 1 mitigates motor and neuropathological deficits in genetic mouse models of Machado–Joseph disease I Nascimento-Ferreira, C Nobrega, A Vasconcelos-Ferreira, I Onofre, ... Brain 136 (7), 2173-2188, 2013 | 109 | 2013 |
| Intravenous administration of brain-targeted stable nucleic acid lipid particles alleviates Machado-Joseph disease neurological phenotype M Conceição, L Mendonça, C Nóbrega, C Gomes, P Costa, H Hirai, ... Biomaterials 82, 124-137, 2016 | 99 | 2016 |
| Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation? A Marcelo, R Koppenol, LP de Almeida, CA Matos, C Nóbrega Cell death & disease 12 (6), 592, 2021 | 97 | 2021 |
| MicroRNA-21 silencing enhances the cytotoxic effect of the antiangiogenic drug sunitinib in glioblastoma PM Costa, AL Cardoso, C Nobrega, LF Pereira de Almeida, JN Bruce, ... Human molecular genetics 22 (5), 904-918, 2013 | 94 | 2013 |
| Transplantation of cerebellar neural stem cells improves motor coordination and neuropathology in Machado-Joseph disease mice LS Mendonça, C Nobrega, H Hirai, BK Kaspar, L Pereira de Almeida Brain 138 (2), 320-335, 2015 | 92 | 2015 |
| Neuropeptide Y stimulates autophagy in hypothalamic neurons CA Aveleira, M Botelho, S Carmo-Silva, JF Pascoal, M Ferreira-Marques, ... Proceedings of the National Academy of Sciences 112 (13), E1642-E1651, 2015 | 81 | 2015 |
| Association of FTO Polymorphisms with Obesity and Obesity-Related Outcomes in Portuguese Children D Albuquerque, C Nóbrega, L Manco PloS one 8 (1), e54370, 2013 | 80 | 2013 |
| Moderate long-term modulation of neuropeptide Y in hypothalamic arcuate nucleus induces energy balance alterations in adult rats L Sousa-Ferreira, M Garrido, I Nascimento-Ferreira, C Nobrega, ... PLoS One 6 (7), e22333, 2011 | 64 | 2011 |
| MSGP: the first database of the protein components of the mammalian stress granules C Nunes, I Mestre, A Marcelo, R Koppenol, CA Matos, C Nóbrega Database 2019, baz031, 2019 | 62 | 2019 |
| Restoring brain cholesterol turnover improves autophagy and has therapeutic potential in mouse models of spinocerebellar ataxia C Nóbrega, L Mendonça, A Marcelo, A Lamazière, S Tomé, G Despres, ... Acta Neuropathologica 138, 837-858, 2019 | 60 | 2019 |
| Association study of common polymorphisms in MSRA, TFAP2B, MC4R, NRXN3, PPARGC1A, TMEM18, SEC16B, HOXB5 and OLFM4 genes with obesity-related traits among Portuguese children D Albuquerque, C Nóbrega, R Rodríguez-López, L Manco Journal of human genetics 59 (6), 307-313, 2014 | 56 | 2014 |
| Ataxin-3 phosphorylation decreases neuronal defects in spinocerebellar ataxia type 3 models CA Matos, C Nóbrega, SR Louros, B Almeida, E Ferreiro, J Valero, ... Journal of Cell Biology 212 (4), 465-480, 2016 | 48 | 2016 |
| Re-establishing ataxin-2 downregulates translation of mutant ataxin-3 and alleviates Machado–Joseph disease C Nobrega, S Carmo-Silva, D Albuquerque, A Vasconcelos-Ferreira, ... Brain 138 (12), 3537-3554, 2015 | 48 | 2015 |
| Overexpression of mutant ataxin-3 in mouse cerebellum induces ataxia and cerebellar neuropathology C Nóbrega, I Nascimento-Ferreira, I Onofre, D Albuquerque, M Conceição, ... The Cerebellum 12, 441-455, 2013 | 45 | 2013 |
