The latent promiscuity of newly identified microbial lactonases is linked to recently diverged phosphotriesterase TDS 1. Afriat L, Roodveldt C, Manco G Biochemistry, 2006 | 300 | 2006 |
The role of protein dynamics in the evolution of new enzyme function E Campbell, M Kaltenbach, GJ Correy, PD Carr, BT Porebski, ... Nature chemical biology 12 (11), 944-950, 2016 | 287 | 2016 |
Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme N Tokuriki, CJ Jackson, L Afriat-Jurnou, KT Wyganowski, R Tang, ... Nature Communications 3 (1), 1257, 2012 | 231 | 2012 |
Reconstructing a missing link in the evolution of a recently diverged phosphotriesterase by active-site loop remodeling L Afriat-Jurnou, CJ Jackson, DS Tawfik Biochemistry 51 (31), 6047-6055, 2012 | 148 | 2012 |
Conformational sampling, catalysis, and evolution of the bacterial phosphotriesterase ODL Jackson CJ, Foo JL, Tokuriki N, Afriat L, Carr PD, Kim HK, Schenk G ... Proc Natl Acad Sci U S A., 2009 | 134* | 2009 |
Sequence–structure–function classification of a catalytically diverse oxidoreductase superfamily in Mycobacteria FH Ahmed, PD Carr, BM Lee, L Afriat-Jurnou, AE Mohamed, NS Hong, ... Journal of molecular biology 427 (22), 3554-3571, 2015 | 79 | 2015 |
Predicting nitroimidazole antibiotic resistance mutations in Mycobacterium tuberculosis with protein engineering BM Lee, LK Harold, DV Almeida, L Afriat-Jurnou, HL Aung, BM Forde, ... PLoS pathogens 16 (2), e1008287, 2020 | 63 | 2020 |
Bacterial Quorum-Quenching Lactonase Hydrolyzes Fungal Mycotoxin and Reduces Pathogenicity of Penicillium expansum—Suggesting a Mechanism of … S Dor, D Prusky, L Afriat-Jurnou Journal of Fungi 7 (10), 826, 2021 | 17 | 2021 |
Directed enzyme evolution and encapsulation in peptide nanospheres of quorum quenching lactonase as an antibacterial treatment against plant pathogen D Gurevich, S Dor, M Erov, Y Dan, JC Moy, O Mairesse, M Dafny-Yelin, ... ACS Applied Materials & Interfaces 13 (2), 2179-2188, 2021 | 17 | 2021 |
New homologues of Brassicaceae water‐soluble chlorophyll proteins shed light on chlorophyll binding, spectral tuning, and molecular evolution V Prabahar, L Afriat‐Jurnou, I Paluy, Y Peleg, D Noy The FEBS journal 287 (5), 991-1004, 2020 | 13 | 2020 |
Directed evolution of an endoinulinase from Talaromyces purpureogenus toward efficient production of inulooligosaccharides L Afriat‐Jurnou, R Cohen, I Paluy, R Ben‐Adiva, I Yadid Biotechnology Progress 34 (4), 868-877, 2018 | 10 | 2018 |
Identification and Characterization of a New Quorum-Quenching N-acyl Homoserine Lactonase in the Plant Pathogen Erwinia amylovora S Ya’ar Bar, S Dor, M Erov, L Afriat-Jurnou Journal of Agricultural and Food Chemistry 69 (20), 5652-5662, 2021 | 8 | 2021 |
Mining marine metagenomes revealed a quorum-quenching lactonase with improved biochemical properties that inhibits the food spoilage bacterium Pseudomonas fluorescens R Haramati, S Dor, D Gurevich, D Levy, D Freund, G Rytwo, I Sharon, ... Applied and Environmental Microbiology 88 (4), e01680-21, 2022 | 7 | 2022 |
Screening collagenase activity in bacterial lysate for directed enzyme applications R Tohar, T Ansbacher, I Sher, L Afriat-Jurnou, E Weinberg, M Gal International Journal of Molecular Sciences 22 (16), 8552, 2021 | 5 | 2021 |
The evolution of nitroimidazole antibiotic resistance in Mycobacterium tuberculosis BM Lee, DV Almeida, L Afriat-Jurnou, HL Aung, BM Forde, K Hards, ... bioRxiv, 631127, 2019 | 4 | 2019 |
New sustainable treatment against fire blight disease in pears using quorum-sensing disruption. M Dafny-Yelin, D Gurevich, S Dor, M Erov, Y Dan, JC Moy, O Mairesse, ... | | 2023 |
Stabilized mutants of quorum quenching lactonase and use thereof in treatment of pathogens L Afriat-jurnou, E Maayan, D Gurevich, MD Yelin US Patent App. 17/596,740, 2023 | | 2023 |
Compositions comprising aromatic dipeptides-based structures encapsulating an esterase and uses thereof L Adler-Abramovich, L Afriat-jurnou US Patent App. 18/002,251, 2023 | | 2023 |
Endoinulinases I Yadid, R Cohen, L Afriat-jurnou US Patent 11,655,463, 2023 | | 2023 |
Lactonase and stabilized mutants thereof for treating fungal infections in plants L Afriat-jurnou, D Prusky | | 2022 |