A novel murine model to deplete hepatic stellate cells uncovers their role in amplifying liver damage in mice JE Puche, YA Lee, J Jiao, C Aloman, MI Fiel, U Muñoz, T Kraus, T Lee, ... Hepatology 57 (1), 339-350, 2013 | 157 | 2013 |
Glucokinase links Krüppel‐like factor 6 to the regulation of hepatic insulin sensitivity in nonalcoholic fatty liver disease LP Bechmann, A Gastaldelli, D Vetter, GL Patman, L Pascoe, ... Hepatology 55 (4), 1083-1093, 2012 | 76 | 2012 |
Hepatocyte growth factor enhances alternative splicing of the Krüppel-like factor 6 (KLF6) tumor suppressor to promote growth through SRSF1 Ú Muñoz, JE Puche, R Hannivoort, UE Lang, M Cohen-Naftaly, ... Molecular Cancer Research 10 (9), 1216-1227, 2012 | 73 | 2012 |
Post-transcriptional activation of PPAR alpha by KLF6 in hepatic steatosis LP Bechmann, D Vetter, J Ishida, RA Hannivoort, UE Lang, ... Journal of hepatology 58 (5), 1000-1006, 2013 | 68 | 2013 |
Enhanced proteasome-dependent degradation of the CDK inhibitor p27kip1 in immortalized lymphocytes from Alzheimer's dementia patients U Munoz, F Bartolomé, F Bermejo, Á Martín-Requero Neurobiology of aging 29 (10), 1474-1484, 2008 | 57 | 2008 |
GSK3β phosphorylation of the KLF6 tumor suppressor promotes its transactivation of p21 UE Lang, P Kocabayoglu, GZ Cheng, Z Ghiassi-Nejad, U Muñoz, D Vetter, ... Oncogene 32 (38), 4557-4564, 2013 | 56 | 2013 |
HMG-CoA reductase inhibitor simvastatin inhibits cell cycle progression at the G1/S checkpoint in immortalized lymphocytes from Alzheimer's disease patients independently of … SG Sala, U Munoz, F Bartolome, F Bermejo, Á Martín-Requero Journal of Pharmacology and Experimental Therapeutics 324 (1), 352-359, 2008 | 50 | 2008 |
Impaired apoptosis in lymphoblasts from Alzheimer’s disease patients: Cross-talk of Ca2+/calmodulin and ERK1/2 signaling pathways F Bartolome, N de Las Cuevas, U Munoz, F Bermejo, A Martin-Requero Cellular and molecular life sciences 64, 1437-1448, 2007 | 49 | 2007 |
Altered liver expression of genes involved in lipid and glucose metabolism in mice with partial IGF-1 deficiency: an experimental approach to metabolic syndrome JR De Ita, I Castilla-Cortázar, GA Aguirre, C Sánchez-Yago, ... Journal of translational medicine 13, 1-13, 2015 | 46 | 2015 |
IGF-1 modulates gene expression of proteins involved in inflammation, cytoskeleton, and liver architecture VJ Lara-Diaz, I Castilla-Cortazar, I Martín-Estal, M García-Magariño, ... Journal of physiology and biochemistry 73, 245-258, 2017 | 42 | 2017 |
An experimental model of partial insulin-like growth factor-1 deficiency in mice I Castilla-Cortazar, L Guerra, JE Puche, U Munoz, R Barhoum, ... Journal of physiology and biochemistry 70, 129-139, 2014 | 33 | 2014 |
Protection against oxidative stress and “IGF-I deficiency conditions” ÚM Morón, I Castilla-Cortázar Antioxidant enzyme 3, 1135-1140, 2012 | 33 | 2012 |
Partial IGF‐1 deficiency induces brain oxidative damage and edema, which are ameliorated by replacement therapy JE Puche, Ú Muñoz, M García‐Magariño, MC Sádaba, I Castilla‐Cortázar Biofactors 42 (1), 60-79, 2016 | 32 | 2016 |
Altered cell cycle‐related gene expression in brain and lymphocytes from a transgenic mouse model of Alzheimer’s disease [amyloid precursor protein/presenilin 1 (PS1)] N Esteras, F Bartolomé, C Alquézar, D Antequera, U Munoz, E Carro, ... European Journal of Neuroscience 36 (5), 2609-2618, 2012 | 31 | 2012 |
Altered transcriptional regulators in response to serum in immortalized lymphocytes from Alzheimer's disease patients N De las Cuevas, Ú Muñoz, OG Hermida, Á Martín-Requero Neurobiology of aging 26 (5), 615-624, 2005 | 30 | 2005 |
Partial IGF-1 deficiency is sufficient to reduce heart contractibility, angiotensin II sensibility, and alter gene expression of structural and functional cardiac proteins JL González-Guerra, I Castilla-Cortazar, GA Aguirre, Ú Muñoz, ... PLoS One 12 (8), e0181760, 2017 | 24 | 2017 |
Altered calmodulin degradation and signaling in non-neuronal cells from Alzheimer’s disease patients N Esteras, Ú Muñoz, C Alquézar, F Bartolomé, F Bermejo-Pareja, ... Current Alzheimer Research 9 (3), 267-277, 2012 | 24 | 2012 |
Main role of antibodies in demyelination and axonal damage in multiple sclerosis U Muñoz, C Sebal, E Escudero, M Esiri, J Tzartos, C Sloan, MC Sadaba Cellular and Molecular Neurobiology 42 (6), 1809-1827, 2022 | 18 | 2022 |
Mechanisms underlying testicular damage and dysfunction in mice with partial IGF-1 deficiency and the effectiveness of IGF-1 replacement therapy I Castilla-Cortázar, A Gago, Ú Muñoz, E Ávila-Gallego, ... Urology 86 (6), 1241. e1-1241. e9, 2015 | 18 | 2015 |
Distinct regulation of cell cycle and survival in lymphocytes from patients with Alzheimer's disease and amyotrophic lateral sclerosis F Bartolomé, Ú Muñoz, N Esteras, J Esteban, F Bermejo-Pareja, ... International journal of clinical and experimental pathology 2 (4), 390, 2009 | 18 | 2009 |