| Impaired action potential initiation in GABAergic interneurons causes hyperexcitable networks in an epileptic mouse model carrying a human NaV1. 1 mutation UBS Hedrich, C Liautard, D Kirschenbaum, M Pofahl, J Lavigne, Y Liu, ... Journal of Neuroscience 34 (45), 14874-14889, 2014 | 160 | 2014 |
| A novel approach to describe a U1 snRNA binding site M Freund, C Asang, S Kammler, C Konermann, J Krummheuer, M Hipp, ... Nucleic acids research 31 (23), 6963-6975, 2003 | 119 | 2003 |
| Genomic HEXploring allows landscaping of novel potential splicing regulatory elements S Erkelenz, S Theiss, M Otte, M Widera, JO Peter, H Schaal Nucleic acids research 42 (16), 10681-10697, 2014 | 95 | 2014 |
| Implications for hyperhomocysteinemia: not homocysteine but its oxidized forms strongly inhibit neuronal network activity P Görtz, A Hoinkes, W Fleischer, F Otto, B Schwahn, U Wendel, M Siebler Journal of the neurological sciences 218 (1-2), 109-114, 2004 | 94 | 2004 |
| Store-operated calcium entry modulates neuronal network activity in a model of chronic epilepsy JA Steinbeck, N Henke, J Opatz, J Gruszczynska-Biegala, L Schneider, ... Experimental neurology 232 (2), 185-194, 2011 | 88 | 2011 |
| Niche-dependent development of functional neuronal networks from embryonic stem cell-derived neural populations S Illes, S Theiss, HP Hartung, M Siebler, M Dihné BMC neuroscience 10, 1-16, 2009 | 84 | 2009 |
| Comparative performance analysis of human iPSC-derived and primary neural progenitor cells (NPC) grown as neurospheres in vitro M Hofrichter, L Nimtz, J Tigges, Y Kabiri, F Schröter, B Royer-Pokora, ... Stem cell research 25, 72-82, 2017 | 72 | 2017 |
| Cryopreserved rat cortical cells develop functional neuronal networks on microelectrode arrays F Otto, P Görtz, W Fleischer, M Siebler Journal of neuroscience methods 128 (1-2), 173-181, 2003 | 67 | 2003 |
| Correct mRNA processing at a mutant TT splice donor in FANCC ameliorates the clinical phenotype in patients and is enhanced by delivery of suppressor U1 snRNAs L Hartmann, K Neveling, S Borkens, H Schneider, M Freund, E Grassman, ... The American Journal of Human Genetics 87 (4), 480-493, 2010 | 65 | 2010 |
| Diagnostics of pathogenic splicing mutations: does bioinformatics cover all bases L Hartmann, S Theiss, D Niederacher, H Schaal Front Biosci 13 (9), 3252-3272, 2008 | 62 | 2008 |
| Balanced splicing at the Tat-specific HIV-1 3′ ss A3 is critical for HIV-1 replication S Erkelenz, F Hillebrand, M Widera, S Theiss, A Fayyaz, D Degrandi, ... Retrovirology 12, 1-19, 2015 | 49 | 2015 |
| Neuronal network properties of human teratocarcinoma cell line-derived neurons P Görtz, W Fleischer, C Rosenbaum, F Otto, M Siebler Brain Research 1018 (1), 18-25, 2004 | 42 | 2004 |
| Cell assembly signatures defined by short-term synaptic plasticity in cortical networks L Carrillo-Reid, VG Lopez-Huerta, M Garcia-Munoz, S Theiss, ... International journal of neural systems 25 (07), 1550026, 2015 | 36 | 2015 |
| Tra2-Mediated Recognition of HIV-1 5′ Splice Site D3 as a Key Factor in the Processing of vpr mRNA S Erkelenz, G Poschmann, S Theiss, A Stefanski, F Hillebrand, M Otte, ... Journal of virology 87 (5), 2721-2734, 2013 | 36 | 2013 |
| Robust generation of person-specific, synchronously active neuronal networks using purely isogenic human iPSC-3D neural aggregate cultures J Izsak, H Seth, M Andersson, D Vizlin-Hodzic, S Theiss, E Hanse, ... Frontiers in Neuroscience 13, 351, 2019 | 34 | 2019 |
| Comparative in silico analyses and experimental validation of novel splice site and missense mutations in the genes MLH1 and MSH2 B Betz, S Theiss, M Aktas, C Konermann, TO Goecke, G Möslein, ... Journal of cancer research and clinical oncology 136, 123-134, 2010 | 31 | 2010 |
| Characterization and application of electrically active neuronal networks established from human induced pluripotent stem cell-derived neural progenitor cells for neurotoxicity … L Nimtz, J Hartmann, J Tigges, S Masjosthusmann, M Schmuck, E Keßel, ... Stem Cell Research 45, 101761, 2020 | 28 | 2020 |
| Analysis of competing HIV-1 splice donor sites uncovers a tight cluster of splicing regulatory elements within exon 2/2b AL Brillen, L Walotka, F Hillebrand, L Müller, M Widera, S Theiss, ... Journal of Virology 91 (14), 10.1128/jvi. 00389-17, 2017 | 25 | 2017 |
| Succession of splicing regulatory elements determines cryptic 5΄ ss functionality AL Brillen, K Schöneweis, L Walotka, L Hartmann, L Müller, J Ptok, ... Nucleic Acids Research 45 (7), 4202-4216, 2017 | 23 | 2017 |
| Ranking noncanonical 5′ splice site usage by genome-wide RNA-seq analysis and splicing reporter assays S Erkelenz, S Theiss, W Kaisers, J Ptok, L Walotka, L Müller, F Hillebrand, ... Genome research 28 (12), 1826-1840, 2018 | 21 | 2018 |
