Follow
Charles Loftin
Charles Loftin
University of Kentucky
No verified email
Title
Cited by
Cited by
Year
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
R Langenbach, SG Morham, HF Tiano, CD Loftin, BI Ghanayem, ...
Cell 83 (3), 483-492, 1995
14051995
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
SG Morham, R Langenbach, CD Loftin, HF Tiano, N Vouloumanos, ...
Cell 83 (3), 473-482, 1995
13471995
Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis
HF Tiano, CD Loftin, J Akunda, CA Lee, J Spalding, A Sessoms, ...
Cancer research 62 (12), 3395-3401, 2002
4212002
Cyclooxygenase knockout mice: models for elucidating isoform-specific functions
R Langenbach, C Loftin, C Lee, H Tiano
Biochemical pharmacology 58 (8), 1237-1246, 1999
2821999
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2
CD Loftin, DB Trivedi, HF Tiano, JA Clark, CA Lee, JA Epstein, ...
Proceedings of the National Academy of Sciences 98 (3), 1059-1064, 2001
2692001
Cyclooxygenase‐deficient mice: a summary of their characteristics and susceptibilities to inflammation and carcinogenesis
R Langenbach, CD Loftin, C Lee, H Tiano
Annals of the New York Academy of Sciences 889 (1), 52-61, 1999
2121999
Selective cyclooxygenase-2 inhibition with celecoxib decreases angiotensin II-induced abdominal aortic aneurysm formation in mice
VL King, DB Trivedi, JM Gitlin, CD Loftin
Arteriosclerosis, thrombosis, and vascular biology 26 (5), 1137-1143, 2006
1562006
Interleukin-1β–induced mucin production in human airway epithelium is mediated by cyclooxygenase-2, prostaglandin E2 receptors, and cyclic AMP-protein kinase A signaling
T Gray, P Nettesheim, C Loftin, JS Koo, J Bonner, S Peddada, ...
Molecular pharmacology 66 (2), 337-346, 2004
1452004
Phenotypes of the COX-deficient mice indicate physiological and pathophysiological roles for COX-1 and COX-2
CD Loftin, HF Tiano, R Langenbach
Prostaglandins & other lipid mediators 68, 177-185, 2002
1452002
Expression and regulation of nonsteroidal anti-inflammatory drug–activated gene (NAG-1) in human and mouse tissue
KS Kim, SJ Baek, GP Flake, CD Loftin, BF Calvo, TE Eling
Gastroenterology 122 (5), 1388-1398, 2002
1452002
Generation of a conditional allele of the mouse prostaglandin EP4 receptor
A Schneider, YF Guan, Y Zhang, MA Magnuson, C Pettepher, CD Loftin, ...
Genesis 40 (1), 7-14, 2004
1072004
Genetic deficiency of cyclooxygenase-2 attenuates abdominal aortic aneurysm formation in mice
JM Gitlin, DB Trivedi, R Langenbach, CD Loftin
Cardiovascular research 73 (1), 227-236, 2007
1002007
Cyclooxygenase-2 deficiency attenuates adipose tissue differentiation and inflammation in mice
S Ghoshal, DB Trivedi, GA Graf, CD Loftin
Journal of Biological Chemistry 286 (1), 889-898, 2011
982011
Cyclooxygenase-1–selective inhibition prolongs gestation in mice without adverse effects on the ductus arteriosus
CD Loftin, DB Trivedi, R Langenbach
The Journal of clinical investigation 110 (4), 549-557, 2002
932002
Cyclooxygenase-2 inhibition increases lipopolysaccharide-induced atherosclerosis in mice
JM Gitlin, CD Loftin
Cardiovascular research 81 (2), 400-407, 2009
812009
Diclofenac enables prolonged delivery of naltrexone through microneedle-treated skin
SL Banks, KS Paudel, NK Brogden, CD Loftin, AL Stinchcomb
Pharmaceutical research 28, 1211-1219, 2011
742011
Effects of genetic deficiency of cyclooxygenase-1 or cyclooxygenase-2 on functional and histological outcomes following traumatic brain injury in mice
ML Kelso, SW Scheff, JR Pauly, CD Loftin
BMC neuroscience 10, 1-9, 2009
492009
Structure-based discovery of mPGES-1 inhibitors suitable for preclinical testing in wild-type mice as a new generation of anti-inflammatory drugs
K Ding, Z Zhou, S Hou, Y Yuan, S Zhou, X Zheng, J Chen, C Loftin, ...
Scientific reports 8 (1), 5205, 2018
472018
Cyclooxygenase-2 inhibition attenuates abdominal aortic aneurysm progression in hyperlipidemic mice
S Ghoshal, CD Loftin
PloS one 7 (11), e44369, 2012
402012
β-Arrestin-2 deficiency attenuates abdominal aortic aneurysm formation in mice
DB Trivedi, CD Loftin, J Clark, P Myers, LM DeGraff, J Cheng, DC Zeldin, ...
Circulation research 112 (9), 1219-1229, 2013
362013
The system can't perform the operation now. Try again later.
Articles 1–20