| Direct, one-pot sequential reductive alkylation of lactams/amides with Grignard and organolithium reagents through lactam/amide activation. KJ Xiao, JM Luo, KY Ye, Y Wang, PQ Huang ChemInform 41 (32), i, 2010 | 269 | 2010 |
| Direct transformation of secondary amides into secondary amines: triflic anhydride activated reductive alkylation KJ Xiao, AE Wang, PQ Huang Angewandte Chemie 124 (33), 8439-8442, 2012 | 209 | 2012 |
| The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK Y Zhan, Y Chen, Q Zhang, J Zhuang, M Tian, H Chen, L Zhang, H Zhang, ... Nature chemical biology 8 (11), 897-904, 2012 | 179 | 2012 |
| Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway W Wang, Y Wang, H Chen, Y Xing, F Li, Q Zhang, B Zhou, H Zhang, ... Nature chemical biology 10 (2), 133-140, 2014 | 158 | 2014 |
| Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation L Li, Y Liu, H Chen, F Li, J Wu, H Zhang, J He, Y Xing, Y Chen, W Wang, ... Nature chemical biology 11 (5), 339-346, 2015 | 154 | 2015 |
| NSAID sulindac and its analog bind RXRα and inhibit RXRα-dependent AKT signaling H Zhou, W Liu, Y Su, Z Wei, J Liu, SK Kolluri, H Wu, Y Cao, J Chen, Y Wu, ... Cancer cell 17 (6), 560-573, 2010 | 135 | 2010 |
| A Unique Pharmacophore for Activation of the Nuclear Orphan Receptor Nur77 In vivo and In vitro J Liu, H Zeng, L Zhang, Y Zhan, Y Chen, Y Wang, J Wang, S Xiang, W Liu, ... Cancer research 70 (9), 3628-3637, 2010 | 127 | 2010 |
| Versatile one-pot reductive alkylation of Lactams/Amides via amide activation: Application to the concise syntheses of bioactive alkaloids (±)-Bgugaine,(±)-Coniine,(+)-Preussin … KJ Xiao, Y Wang, KY Ye, PQ Huang Chem. Eur. J 16, 12792-12796, 2010 | 121 | 2010 |
| Chemoselective reductive alkynylation of tertiary amides by Ir and Cu (I) bis-metal sequential catalysis PQ Huang, W Ou, F Han Chemical communications 52 (80), 11967-11970, 2016 | 112 | 2016 |
| Asymmetric synthesis of (+)-L-733, 060 and (+)-CP-99, 994 based on a new chiral 3-piperidinol synthon PQ Huang, LX Liu, BG Wei, YP Ruan Organic Letters 5 (11), 1927-1929, 2003 | 112 | 2003 |
| Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols CX Ye, YY Melcamu, HH Li, JT Cheng, TT Zhang, YP Ruan, X Zheng, ... Nature communications 9 (1), 410, 2018 | 105 | 2018 |
| An easy access to protected (4S, 5R)-5-alkyl-4-hydroxy-2-pyrrolidinones and their use as versatile synthetic intermediates PQ Huang, SL Wang, JL Ye, YP Ruan, YQ Huang, H Zheng, JX Gao Tetrahedron 54 (41), 12547-12560, 1998 | 94 | 1998 |
| Direct transformations of amides: Tactics and recent progress PQ Huang Acta Chimica Sinica 76 (5), 357, 2018 | 92 | 2018 |
| General One‐Pot Reductive gem‐Bis‐Alkylation of Tertiary Lactams/Amides: Rapid Construction of 1‐Azaspirocycles and Formal Total Synthesis of … KJ Xiao, JM Luo, XE Xia, Y Wang, PQ Huang Chemistry–A European Journal 19 (39), 13075-13086, 2013 | 91 | 2013 |
| DIBAL–H–H2NR and DIBAL–H–HNR1R2· HCl complexes for efficient conversion of lactones and esters to amides PQ Huang, X Zheng, XM Deng Tetrahedron Letters 42 (51), 9039-9041, 2001 | 89 | 2001 |
| Efficient and chemoselective alkylation of amines/amino acids using alcohols as alkylating reagents under mild conditions CP Xu, ZH Xiao, BQ Zhuo, YH Wang, PQ Huang Chemical communications 46 (41), 7834-7836, 2010 | 86 | 2010 |
| A Versatile Approach for the Asymmetric Syntheses of (1R,9aR)-Epiquinamide and (1R,9aR)-Homopumiliotoxin 223G PQ Huang, ZQ Guo, YP Ruan Organic Letters 8 (7), 1435-1438, 2006 | 84 | 2006 |
| Metal-free C–H alkyliminylation and acylation of alkenes with secondary amides PQ Huang, YH Huang, H Geng, JL Ye Scientific Reports 6 (1), 28801, 2016 | 82 | 2016 |
| Asymmetric synthesis of hydroxylated pyrrolidines, piperidines and related bioactive compounds: From N-acyliminium chemistry to N-α-carbanion chemistry PQ Huang Synlett 2006 (08), 1133-1149, 2006 | 81 | 2006 |
| A general method for the one-pot reductive functionalization of secondary amides PQ Huang, YH Huang, KJ Xiao, Y Wang, XE Xia The Journal of Organic Chemistry 80 (5), 2861-2868, 2015 | 80 | 2015 |
