| The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1α L Zhong, A D'Urso, D Toiber, C Sebastian, RE Henry, DD Vadysirisack, ... Cell 140 (2), 280-293, 2010 | 1121 | 2010 |
| Function of alternative splicing S Stamm, S Ben-Ari, I Rafalska, Y Tang, Z Zhang, D Toiber, TA Thanaraj, ... Gene 344, 1-20, 2005 | 1102 | 2005 |
| The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism C Sebastián, BMM Zwaans, DM Silberman, M Gymrek, A Goren, L Zhong, ... Cell 151 (6), 1185-1199, 2012 | 695 | 2012 |
| SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodeling D Toiber, F Erdel, K Bouazoune, DM Silberman, L Zhong, P Mulligan, ... Molecular cell 51 (4), 454-468, 2013 | 381 | 2013 |
| A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development P Mulligan, F Yang, L Di Stefano, JY Ji, J Ouyang, JL Nishikawa, D Toiber, ... Molecular cell 42 (5), 689-699, 2011 | 225 | 2011 |
| Sirt1 Is a Regulator of Bone Mass and a Repressor of Sost Encoding for Sclerostin, a Bone Formation Inhibitor E Cohen-Kfir, H Artsi, A Levin, E Abramowitz, A Bajayo, I Gurt, L Zhong, ... Endocrinology 152 (12), 4514-4524, 2011 | 201 | 2011 |
| Neuroprotective functions for the histone deacetylase SIRT6 S Kaluski, M Portillo, A Besnard, D Stein, M Einav, L Zhong, U Ueberham, ... Cell reports 18 (13), 3052-3062, 2017 | 136 | 2017 |
| Combinatorial Complexity of 5′ Alternative Acetylcholinesterase Transcripts and Protein Products*[boxs] E Meshorer, D Toiber, D Zurel, I Sahly, A Dori, E Cagnano, L Schreiber, ... Journal of Biological Chemistry 279 (28), 29740-29751, 2004 | 132 | 2004 |
| N-acetylcholinesterase-induced apoptosis in Alzheimer's disease D Toiber, A Berson, D Greenberg, N Melamed-Book, S Diamant, H Soreq PloS one 3 (9), e3108, 2008 | 111 | 2008 |
| SIRT6 is a DNA double-strand break sensor L Onn, M Portillo, S Ilic, G Cleitman, D Stein, S Kaluski, I Shirat, ... Elife 9, e51636, 2020 | 105 | 2020 |
| SC35 promotes sustainable stress-induced alternative splicing of neuronal acetylcholinesterase mRNA E Meshorer, B Bryk, D Toiber, J Cohen, E Podoly, A Dori, H Soreq Molecular psychiatry 10 (11), 985-997, 2005 | 95 | 2005 |
| Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations D Toiber, G Azkona, S Ben-Ari, N Torán, H Soreq, M Dierssen Neurobiology of disease 40 (1), 348-359, 2010 | 74 | 2010 |
| TOX regulates growth, DNA repair, and genomic instability in T-cell acute lymphoblastic leukemia R Lobbardi, J Pinder, B Martinez-Pastor, M Theodorou, JS Blackburn, ... Cancer discovery 7 (11), 1336-1353, 2017 | 57 | 2017 |
| ARDD 2020: from aging mechanisms to interventions GV Mkrtchyan, K Abdelmohsen, P Andreux, I Bagdonaite, N Barzilai, ... Aging (Albany NY) 12 (24), 24484, 2020 | 54 | 2020 |
| Characterization of nuclear sirtuins: molecular mechanisms and physiological relevance D Toiber, C Sebastian, R Mostoslavsky Histone Deacetylases: the Biology and Clinical Implication, 189-224, 2011 | 52 | 2011 |
| Epigenetic control of early neurodegenerative events in diabetic retinopathy by the histone deacetylase SIRT 6 MA Zorrilla‐Zubilete, A Yeste, FJ Quintana, D Toiber, R Mostoslavsky, ... Journal of neurochemistry 144 (2), 128-138, 2018 | 51 | 2018 |
| Cellular stress reactions as putative cholinergic links in Alzheimer’s disease D Toiber, H Soreq Neurochemical research 30, 909-919, 2005 | 37 | 2005 |
| Pro-apoptotic protein–protein interactions of the extended N-AChE terminus D Toiber, DS Greenberg, H Soreq Journal of neural transmission 116, 1435-1442, 2009 | 36 | 2009 |
| Unraveling the hidden role of a uORF-encoded peptide as a kinase inhibitor of PKCs DR Jayaram, S Frost, C Argov, VB Liju, NP Anto, A Muraleedharan, ... Proceedings of the National Academy of Sciences 118 (40), e2018899118, 2021 | 34 | 2021 |
| Impaired innate and conditioned social behavior in adult C57Bl6/J mice prenatally exposed to chlorpyrifos A Lan, D Stein, M Portillo, D Toiber, O Kofman Behavioral and Brain Functions 15, 1-9, 2019 | 34 | 2019 |
Mostoslavsky, RaulScientific Director, The Massachusetts General Hospital Cancer Center-Harvard Medical SchoolVerified email at mgh.harvard.edu
