Development of novel synthesized phthalazinone-based PARP-1 inhibitors with apoptosis inducing mechanism in lung cancer H Almahli, E Hadchity, MY Jaballah, R Daher, HA Ghabbour, MM Kabil, ... Bioorganic Chemistry 77, 443-456, 2018 | 66 | 2018 |
Facile synthesis and characterization of ZnO nanoparticles for studying their biological activities and photocatalytic degradation properties toward methylene blue dye AA Almehizia, MA Al-Omar, AM Naglah, MA Bhat, NS Al-Shakliah Alexandria Engineering Journal 61 (3), 2386-2395, 2022 | 39 | 2022 |
Identification and characterization of in vivo, in vitro and reactive metabolites of vandetanib using LC–ESI–MS/MS MW Attwa, AA Kadi, HW Darwish, SM Amer, NS Al-Shakliah Chemistry Central Journal 12, 1-16, 2018 | 37 | 2018 |
Identification and characterization of in silico, in vivo, in vitro, and reactive metabolites of infigratinib using LC-ITMS: Bioactivation pathway elucidation and in silico … NS Al-Shakliah, MW Attwa, AA Kadi, H AlRabiah RSC advances 10 (28), 16231-16244, 2020 | 34 | 2020 |
A highly efficient and sensitive LC‐MS/MS method for the determination of afatinib in human plasma: application to a metabolic stability study AA Kadi, AS Abdelhameed, HW Darwish, MW Attwa, NS Al‐Shakliah Biomedical Chromatography 30 (8), 1248-1255, 2016 | 32 | 2016 |
Synthesis, thermogravimetric, and spectroscopic characterizations of three palladium metal (II) ofloxacin drug and amino acids mixed ligand complexes as advanced antimicrobial … AM Naglah, MA Al-Omar, AA Almehizia, HM AlKahtani, MA Bhat, ... Journal of Molecular Structure, 129102, 2020 | 20 | 2020 |
A highly sensitive LC-MS/MS method to determine novel Bruton's tyrosine kinase inhibitor spebrutinib: application to metabolic stability evaluation AS Abdelhameed, MW Attwa, NS Al-Shaklia, AA Kadi Royal Society Open Science 6 (6), 190434, 2019 | 14 | 2019 |
Response surface methodology for optimization of micellar-enhanced spectrofluorimetric method for assay of foretinib in bulk powder and human urine HW Darwish, AH Bakheit, ZS Al-Anazi, NS Al-Shakliah, AM Al-Hossaini, ... Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 257, 119811, 2021 | 13 | 2021 |
Simple and efficient spectroscopic-based univariate sequential methods for simultaneous quantitative analysis of vandetanib, dasatinib, and sorafenib in pharmaceutical … AS Abdelhameed, ES Hassan, MW Attwa, NS Al-Shakliah, AM Alanazi, ... Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 260, 119987, 2021 | 11 | 2021 |
LC-MS/MS method for the quantification of the anti-cancer agent infigratinib: Application for estimation of metabolic stability in human liver microsomes GAE Mostafa, AA Kadi, N AlMasoud, MW Attwa, NS Al-Shakliah, ... Journal of Chromatography B 1179, 122806, 2021 | 11 | 2021 |
Development and validation of an HPLC-UV detection assay for the determination of clonidine in mouse plasma and its application to a pharmacokinetic study H AlRabiah, SM Attia, NS Al-Shakliah, GAE Mostafa molecules 25 (18), 4109, 2020 | 9 | 2020 |
Development of innovative artificial neural networks for simultaneous determination of lapatinib and foretinib in human urine by micellar enhanced synchronous spectrofluorimetry HW Darwish, AH Bakheit, NS Al-Shakliah, IA Darwish Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 238, 118438, 2020 | 9 | 2020 |
Estimation of zorifertinib metabolic stability in human liver microsomes using LC–MS/MS MW Attwa, NS Al-Shakliah, H AlRabiah, AA Kadi, AS Abdelhameed Journal of Pharmaceutical and Biomedical Analysis 211, 114626, 2022 | 8 | 2022 |
Synthesis, spectroscopic, and antimicrobial study of binary and ternary ruthenium (III) complexes of ofloxacin drug and amino acids as secondary ligands AM Naglah, MA Al-Omar, AA Almehizia, AJ Obaidullah, MA Bhat, ... Crystals 10 (3), 225, 2020 | 8 | 2020 |
A validated lc–ms/ms assay for the simultaneous quantification of the fda-approved anticancer mixture (Encorafenib and binimetinib): Metabolic stability estimation MW Attwa, HW Darwish, NS Al-Shakliah, AA Kadi Molecules 26 (9), 2717, 2021 | 7 | 2021 |
Facile synthesis of magnesium oxide nanoparticles for studying their photocatalytic activities against orange G Dye and biological activities against some bacterial and fungal … FK Algethami, HA Katouah, MA Al-Omar, AA Almehizia, AEGE Amr, ... Journal of Inorganic and Organometallic Polymers and Materials 31, 2150-2160, 2021 | 7 | 2021 |
Exploiting the 4-Hydrazinobenzoic acid moiety for the development of anticancer agents: Synthesis and biological profile HA Abuelizz, HM Awad, M Marzouk, FA Nasr, AH Bakheit, AM Naglah, ... Bioorganic Chemistry 102, 104098, 2020 | 7 | 2020 |
Development of novel response surface methodology-assisted micellar enhanced synchronous spectrofluorimetric method for determination of vandetanib in tablets, human plasma and … HW Darwish, AH Bakheit, NS Al-Shakliah, IA Darwish Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 213, 272-280, 2019 | 7 | 2019 |
Synthesis, characterization and antidiabetic effects of vanadyl (II) adenosine monophosphate amino acid mixed-ligand complexes AM Naglah, MA Al-Omar, A Kalmouch, AMA Alsuhaibani, ... Future Medicinal Chemistry 11 (3), 193-210, 2019 | 7 | 2019 |
In vitro investigation of metabolic profiling of newly developed topoisomerase inhibitors (ethyl fluorescein hydrazones, EtFLHs) in RLMs by LC–MS/MS AA Kadi, NS Al-Shakliah, W Yin, AFMM Rahman Journal of Chromatography B 1054, 93-104, 2017 | 7 | 2017 |