| Exploring the repeat protein universe through computational protein design TJ Brunette, F Parmeggiani, PS Huang, G Bhabha, DC Ekiert, ... Nature 528 (7583), 580-584, 2015 | 286 | 2015 |
| De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy PS Huang, K Feldmeier, F Parmeggiani, DA Fernandez Velasco, ... Nature chemical biology 12 (1), 29-34, 2016 | 274 | 2016 |
| Designed armadillo repeat proteins as general peptide-binding scaffolds: consensus design and computational optimization of the hydrophobic core F Parmeggiani, R Pellarin, AP Larsen, G Varadamsetty, MT Stumpp, ... Journal of molecular biology 376 (5), 1282-1304, 2008 | 165 | 2008 |
| Computational design of self-assembling cyclic protein homo-oligomers JA Fallas, G Ueda, W Sheffler, V Nguyen, DE McNamara, B Sankaran, ... Nature chemistry 9 (4), 353-360, 2017 | 154 | 2017 |
| Rational design of α-helical tandem repeat proteins with closed architectures L Doyle, J Hallinan, J Bolduc, F Parmeggiani, D Baker, BL Stoddard, ... Nature 528 (7583), 585-588, 2015 | 144 | 2015 |
| Thermodynamic benchmark study using Biacore technology I Navratilova, GA Papalia, RL Rich, D Bedinger, S Brophy, B Condon, ... Analytical Biochemistry 364 (1), 67-77, 2007 | 118 | 2007 |
| Control of repeat-protein curvature by computational protein design K Park, BW Shen, F Parmeggiani, PS Huang, BL Stoddard, D Baker Nature structural & molecular biology 22 (2), 167-174, 2015 | 102 | 2015 |
| A general computational approach for repeat protein design F Parmeggiani, PS Huang, S Vorobiev, R Xiao, K Park, S Caprari, M Su, ... Journal of molecular biology 427 (2), 563-575, 2015 | 95 | 2015 |
| Designed Armadillo repeat proteins: library generation, characterization and selection of peptide binders with high specificity G Varadamsetty, D Tremmel, S Hansen, F Parmeggiani, A Plückthun Journal of molecular biology 424 (1-2), 68-87, 2012 | 71 | 2012 |
| Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases S Baxter, AR Lambert, R Kuhar, J Jarjour, N Kulshina, F Parmeggiani, ... Nucleic acids research 40 (16), 7985-8000, 2012 | 57 | 2012 |
| Designing repeat proteins: a modular approach to protein design F Parmeggiani, PS Huang Current Opinion in Structural Biology 45, 116-123, 2017 | 49 | 2017 |
| Optimization of designed armadillo repeat proteins by molecular dynamics simulations and NMR spectroscopy P Alfarano, G Varadamsetty, C Ewald, F Parmeggiani, R Pellarin, O Zerbe, ... Protein Science 21 (9), 1298-1314, 2012 | 44 | 2012 |
| Computational design of a homotrimeric metalloprotein with a trisbipyridyl core JH Mills, W Sheffler, ME Ener, PJ Almhjell, G Oberdorfer, JH Pereira, ... Proceedings of the National Academy of Sciences 113 (52), 15012-15017, 2016 | 43 | 2016 |
| Extreme stability in de novo-designed repeat arrays is determined by unusually stable short-range interactions K Geiger-Schuller, K Sforza, M Yuhas, F Parmeggiani, D Baker, D Barrick Proceedings of the National Academy of Sciences 115 (29), 7539-7544, 2018 | 32 | 2018 |
| Designed armadillo repeat proteins F Parmeggiani, R Pellarin, AP Larsen, G Varadamsetty, MT Stumpp, ... US Patent 9,365,629, 2016 | 27 | 2016 |
| A substitution in the fingers domain of DNA polymerase δ reduces fidelity by altering nucleotide discrimination in the catalytic site MJ Prindle, MW Schmitt, F Parmeggiani, LA Loeb Journal of Biological Chemistry 288 (8), 5572-5580, 2013 | 23 | 2013 |
| Computationally designed armadillo repeat proteins for modular peptide recognition C Reichen, S Hansen, C Forzani, A Honegger, SJ Fleishman, T Zhou, ... Journal of molecular biology 428 (22), 4467-4489, 2016 | 22 | 2016 |
| Elfin: An algorithm for the computational design of custom three-dimensional structures from modular repeat protein building blocks CT Yeh, TJ Brunette, D Baker, S McIntosh-Smith, F Parmeggiani Journal of Structural Biology 201 (2), 100-107, 2018 | 16 | 2018 |
| Computer-aided biodesign across scales TE Gorochowski, JR Karr, F Parmeggiani, B Yordanov Frontiers in Bioengineering and Biotechnology 9, 700418, 2021 | 7 | 2021 |
| Precisely patterned nanofibres made from extendable protein multiplexes NP Bethel, AJ Borst, F Parmeggiani, MJ Bick, TJ Brunette, H Nguyen, ... Nature Chemistry 15 (12), 1664-1671, 2023 | 6 | 2023 |
