| Identification of a small molecule nonpeptide active site β-secretase inhibitor that displays a nontraditional binding mode for aspartyl proteases CA Coburn, SJ Stachel, YM Li, DM Rush, TG Steele, E Chen-Dodson, ... Journal of medicinal chemistry 47 (25), 6117-6119, 2004 | 159 | 2004 |
| BACE-1 inhibition by a series of ψ [CH2NH] reduced amide isosteres CA Coburn, SJ Stachel, KG Jones, TG Steele, DM Rush, J DiMuzio, ... Bioorganic & medicinal chemistry letters 16 (14), 3635-3638, 2006 | 77 | 2006 |
| Discovery of aminoheterocycles as a novel β-secretase inhibitor class: pH dependence on binding activity part 1 SJ Stachel, CA Coburn, D Rush, KLG Jones, H Zhu, H Rajapakse, ... Bioorganic & medicinal chemistry letters 19 (11), 2977-2980, 2009 | 67 | 2009 |
| Pyrido 3, 4-B! pyrazines for use as thrombin inhibitors C Coburn, C Kolatac, DM Rush, JP Vacca US Patent 5,869,487, 1999 | 42 | 1999 |
| Bicyclic pyridones as potent, efficacious and orally bioavailable thrombin inhibitors CA Coburn, DM Rush, PD Williams, C Homnick, EA Lyle, SD Lewis, ... Bioorganic & Medicinal Chemistry Letters 10 (10), 1069-1072, 2000 | 29 | 2000 |
| Synthesis of amicetose by three enantioselective methods LA Noecker, JA Martino, PJ Foley, DM Rush, RM Giuliano, FJ Villani Jr Tetrahedron: Asymmetry 9 (2), 203-212, 1998 | 17 | 1998 |
| Identification of Highly Specific Diversity-Oriented Synthesis-Derived Inhibitors of Clostridium difficile JR Duvall, L Bedard, AM Naylor-Olsen, AL Manson, JA Bittker, W Sun, ... ACS infectious diseases 3 (5), 349-359, 2017 | 14 | 2017 |
| BACE-1 inhibition by a series of w [CH2NH] reduced amide isosteres pp 3635–3638 CA Coburn, SJ Stachel, KG Jones, TG Steele, DM Rush, J DiMuzio, ... Bioorganic & Medicinal Chemistry Letters 16 (14), 2006 | | 2006 |
| Design, synthesis, and evaluation of bicyclic pyridones as thrombin inhibitors. C Coburn, D Rush, P Williams, Y Nguyen, C Kolatac, P Sanderson, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 220, U541-U541, 2000 | | 2000 |
| Design, synthesis, and structure activity relationship of a new class of bicyclic thrombin inhibitors. DM Rush, CA Coburn, P Williams, SD Lewis, BJ Lucas, JP Vacca, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 220, U586-U586, 2000 | | 2000 |
