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Daniele M Gilkes
Daniele M Gilkes
Johns Hopkins University School of Medicine
Verified email at jhu.edu - Homepage
Title
Cited by
Cited by
Year
Hypoxia and the extracellular matrix: drivers of tumour metastasis
DM Gilkes, GL Semenza, D Wirtz
Nature Reviews Cancer 14 (6), 430-439, 2014
13772014
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
T Wang, DM Gilkes, N Takano, L Xiang, W Luo, CJ Bishop, P Chaturvedi, ...
Proceedings of the National Academy of Sciences 111 (31), E3234-E3242, 2014
5112014
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation
CCL Wong, DM Gilkes, H Zhang, J Chen, H Wei, P Chaturvedi, SI Fraley, ...
Proceedings of the National Academy of Sciences 108 (39), 16369-16374, 2011
4962011
RETRACTED ARTICLE: HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs
H Zhang, CCL Wong, H Wei, DM Gilkes, P Korangath, P Chaturvedi, ...
Oncogene 31 (14), 1757-1770, 2012
4122012
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
H Zhang, H Lu, L Xiang, JW Bullen, C Zhang, D Samanta, DM Gilkes, ...
Proceedings of the National Academy of Sciences 112 (45), E6215-E6223, 2015
3572015
ATM and Chk2‐dependent phosphorylation of MDMX contribute to p53 activation after DNA damage
L Chen, DM Gilkes, Y Pan, WS Lane, J Chen
The EMBO journal 24 (19), 3411-3422, 2005
3292005
Role of hypoxia-inducible factors in breast cancer metastasis
DM Gilkes, GL Semenza
Future oncology 9 (11), 1623-1636, 2013
3072013
Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis
P Chaturvedi, DM Gilkes, CCL Wong, W Luo, H Zhang, H Wei, N Takano, ...
The Journal of clinical investigation 123 (1), 2012
2982012
MDMX overexpression prevents p53 activation by the MDM2 inhibitor Nutlin
B Hu, DM Gilkes, B Farooqi, SM Sebti, J Chen
Journal of Biological Chemistry 281 (44), 33030-33035, 2006
2862006
Efficient p53 activation and apoptosis by simultaneous disruption of binding to MDM2 and MDMX
B Hu, DM Gilkes, J Chen
Cancer Research 67 (18), 8810-8817, 2007
2602007
Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis
CCL Wong, H Zhang, DM Gilkes, J Chen, H Wei, P Chaturvedi, ME Hubbi, ...
Journal of molecular medicine 90, 803-815, 2012
2532012
Activation of dendritic cells via inhibition of Jak2/STAT3 signaling
Y Nefedova, P Cheng, D Gilkes, M Blaskovich, AA Beg, SM Sebti, ...
The Journal of Immunology 175 (7), 4338-4346, 2005
2342005
BRCA1 and BRCA2 mutations and treatment strategies for breast cancer
I Godet, DM Gilkes
Integrative cancer science and therapeutics 4 (1), 2017
2312017
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
P Chaturvedi, DM Gilkes, N Takano, GL Semenza
Proceedings of the National Academy of Sciences 111 (20), E2120-E2129, 2014
2082014
Hypoxia-inducible factors and cancer
JC Jun, A Rathore, H Younas, D Gilkes, VY Polotsky
Current sleep medicine reports 3, 1-10, 2017
1902017
Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration
H Jayatilaka, P Tyle, JJ Chen, M Kwak, J Ju, HJ Kim, JSH Lee, PH Wu, ...
Nature communications 8 (1), 15584, 2017
1682017
Fate-mapping post-hypoxic tumor cells reveals a ROS-resistant phenotype that promotes metastasis
I Godet, YJ Shin, JA Ju, IC Ye, G Wang, DM Gilkes
Nature communications 10 (1), 4862, 2019
1592019
MDMX regulation of p53 response to ribosomal stress
DM Gilkes, L Chen, J Chen
The EMBO journal 25 (23), 5614-5625, 2006
1542006
Sirtuin-7 inhibits the activity of hypoxia-inducible factors
ME Hubbi, H Hu, DM Gilkes, GL Semenza
Journal of Biological Chemistry 288 (29), 20768-20775, 2013
1502013
Regulation of MDMX nuclear import and degradation by Chk2 and 14‐3‐3
C LeBron, L Chen, DM Gilkes, J Chen
The EMBO journal 25 (6), 1196-1206, 2006
1452006
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