Flow ozonolysis using a semipermeable Teflon AF-2400 membrane to effect gas− liquid contact M O’Brien, IR Baxendale, SV Ley Organic letters 12 (7), 1596-1598, 2010 | 338 | 2010 |
Flow chemistry: intelligent processing of gas–liquid transformations using a tube-in-tube reactor M Brzozowski, M O’Brien, SV Ley, A Polyzos Accounts of chemical research 48 (2), 349-362, 2015 | 319 | 2015 |
The continuous‐flow synthesis of carboxylic acids using CO2 in a tube‐in‐tube gas permeable membrane reactor A Polyzos, M O'Brien, TP Petersen, IR Baxendale, SV Ley Angewandte Chemie-International Edition 50 (5), 1190, 2011 | 261 | 2011 |
Hydrogenation in flow: Homogeneous and heterogeneous catalysis using Teflon AF-2400 to effect gas–liquid contact at elevated pressure M O'Brien, N Taylor, A Polyzos, IR Baxendale, SV Ley Chemical Science 2 (7), 1250-1257, 2011 | 237 | 2011 |
Teflon AF-2400 mediated gas–liquid contact in continuous flow methoxycarbonylations and in-line FTIR measurement of CO concentration P Koos, U Gross, A Polyzos, M O'Brien, I Baxendale, SV Ley Organic & Biomolecular Chemistry 9 (20), 6903-6908, 2011 | 146 | 2011 |
A prototype continuous-flow liquid–liquid extraction system using open-source technology M O'Brien, P Koos, DL Browne, SV Ley Organic & biomolecular chemistry 10 (35), 7031-7036, 2012 | 126 | 2012 |
Flow synthesis using gaseous ammonia in a Teflon AF-2400 tube-in-tube reactor: Paal–Knorr pyrrole formation and gas concentration measurement by inline flow titration PB Cranwell, M O'Brien, DL Browne, P Koos, A Polyzos, M Peña-López, ... Organic & Biomolecular Chemistry 10 (30), 5774-5779, 2012 | 121 | 2012 |
The oxygen‐mediated synthesis of 1, 3‐butadiynes in continuous flow: Using Teflon AF‐2400 to effect gas/liquid contact TP Petersen, A Polyzos, M O'Brien, T Ulven, IR Baxendale, SV Ley ChemSusChem 5 (2), 274-277, 2012 | 119 | 2012 |
Continuous multiple liquid–liquid separation: Diazotization of amino acids in flow DX Hu, M O’Brien, SV Ley Organic letters 14 (16), 4246-4249, 2012 | 111 | 2012 |
Long-term outcomes after endoscopic ultrasound-guided ablation of pancreatic cysts JH Choi, DW Seo, TJ Song, DH Park, SS Lee, SK Lee, MH Kim Endoscopy 49 (09), 866-873, 2017 | 93 | 2017 |
Camera-enabled techniques for organic synthesis SV Ley, RJ Ingham, M O’Brien, DL Browne Beilstein journal of organic chemistry 9 (1), 1051-1072, 2013 | 93 | 2013 |
Scaling up of continuous flow processes with gases using a tube-in-tube reactor: Inline titrations and fanetizole synthesis with ammonia JC Pastre, DL Browne, M O’Brien, SV Ley Organic Process Research & Development 17 (9), 1183-1191, 2013 | 89 | 2013 |
Retinoic acid receptor signaling regulates choroid fissure closure through independent mechanisms in the ventral optic cup and periocular mesenchyme G Lupo, G Gestri, M O'Brien, RM Denton, RAS Chandraratna, SV Ley, ... Proceedings of the National Academy of Sciences 108 (21), 8698-8703, 2011 | 87 | 2011 |
Synthesis of acetal protected building blocks using flow chemistry with flow IR analysis: preparation of butane-2, 3-diacetal tartrates CF Carter, IR Baxendale, M O'Brien, JBJ Pavey, SV Ley Organic & biomolecular chemistry 7 (22), 4594-4597, 2009 | 82 | 2009 |
Flow chemistry syntheses of styrenes, unsymmetrical stilbenes and branched aldehydes SL Bourne, M O'Brien, S Kasinathan, P Koos, P Tolstoy, DX Hu, RW Bates, ... ChemCatChem 5 (1), 159-172, 2013 | 80 | 2013 |
A general continuous flow method for palladium catalysed carbonylation reactions using single and multiple tube‐in‐tube gas‐liquid microreactors U Gross, P Koos, M O'Brien, A Polyzos, SV Ley European Journal of Organic Chemistry 2014 (29), 6418-6430, 2014 | 65 | 2014 |
Syngas-mediated CC bond formation in flow: selective rhodium-catalysed hydroformylation of styrenes S Kasinathan, SL Bourne, P Tolstoy, P Koos, M O’Brien, RW Bates, ... Synlett 2011 (18), 2648-2651, 2011 | 50 | 2011 |
The continuous-flow synthesis of styrenes using ethylene in a palladium-catalysed heck cross-coupling reaction SL Bourne, P Koos, M O’Brien, B Martin, B Schenkel, IR Baxendale, ... Synlett 2011 (18), 2643-2647, 2011 | 48 | 2011 |
Continuous-flow processing of gaseous ammonia using a Teflon AF-2400 tube-in-tube reactor: Synthesis of thioureas and in-line titrations DL Browne, M O’Brien, P Koos, PB Cranwell, A Polyzos, SV Ley Synlett 23 (09), 1402-1406, 2012 | 43 | 2012 |
Harnessing open-source technology for low-cost automation in synthesis: flow chemical deprotection of silyl ethers using a homemade autosampling system M O'Brien, L Konings, M Martin, J Heap Tetrahedron Letters 58 (25), 2409-2413, 2017 | 39 | 2017 |