Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular Aβ clearance J Kim, JM Castellano, H Jiang, JM Basak, M Parsadanian, V Pham, ... Neuron 64 (5), 632-644, 2009 | 277 | 2009 |
Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a IR Chassagnon, CA McCarthy, YKY Chin, SS Pineda, A Keramidas, ... Proceedings of the National Academy of Sciences 114 (14), 3750-3755, 2017 | 194 | 2017 |
Identification and characterization of a new cognitive enhancer based on inhibition of insulin‐regulated aminopeptidase AL Albiston, CJ Morton, HL Ng, V Pham, HR Yeatman, S Ye, ... The FASEB Journal 22 (12), 4209-4217, 2008 | 118 | 2008 |
Interaction of the Akt substrate, AS160, with the glucose transporter 4 vesicle marker protein, insulin-regulated aminopeptidase GR Peck, S Ye, V Pham, RN Fernando, SL Macaulay, SY Chai, ... Molecular endocrinology 20 (10), 2576-2583, 2006 | 113 | 2006 |
Identification and development of specific inhibitors for insulin‐regulated aminopeptidase as a new class of cognitive enhancers AL Albiston, S Diwakarla, RN Fernando, SJ Mountford, HR Yeatman, ... British journal of pharmacology 164 (1), 37-47, 2011 | 105 | 2011 |
Gene knockout of insulin-regulated aminopeptidase: loss of the specific binding site for angiotensin IV and age-related deficit in spatial memory AL Albiston, RN Fernando, HR Yeatman, P Burns, L Ng, D Daswani, ... Neurobiology of learning and memory 93 (1), 19-30, 2010 | 62 | 2010 |
Spatial proximity between a photolabile residue in position 19 of salmon calcitonin and the amino terminus of the human calcitonin receptor V Pham, JD Wade, BW Purdue, PM Sexton Journal of Biological Chemistry 279 (8), 6720-6729, 2004 | 56 | 2004 |
Binding to and inhibition of insulin-regulated aminopeptidase by macrocyclic disulfides enhances spine density S Diwakarla, E Nylander, A Grönbladh, SR Vanga, YS Khan, ... Molecular pharmacology 89 (4), 413-424, 2016 | 46 | 2016 |
Neuronal electrophysiological function and control of neurite outgrowth on electrospun polymer nanofibers are cell type dependent JL Bourke, HA Coleman, V Pham, JS Forsythe, HC Parkington Tissue Engineering Part A 20 (5-6), 1089-1095, 2014 | 38 | 2014 |
Distinct distribution of GLUT4 and insulin regulated aminopeptidase in the mouse kidney AL Albiston, HR Yeatman, V Pham, SJ Fuller, S Diwakarla, RN Fernando, ... Regulatory peptides 166 (1-3), 83-89, 2011 | 35 | 2011 |
Aryl sulfonamide inhibitors of insulin-regulated aminopeptidase enhance spine density in primary hippocampal neuron cultures S Diwakarla, E Nylander, A Gronbladh, SR Vanga, Y Shamsudin, ... ACS chemical neuroscience 7 (10), 1383-1392, 2016 | 34 | 2016 |
Insights into interactions between the α-helical region of the salmon calcitonin antagonists and the human calcitonin receptor using photoaffinity labeling V Pham, M Dong, JD Wade, LJ Miller, CJ Morton, H Ng, MW Parker, ... Journal of Biological Chemistry 280 (31), 28610-28622, 2005 | 32 | 2005 |
Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobic packing point at the active site of insulin-regulated aminopeptidase AL Albiston, V Pham, S Ye, L Ng, RA Lew, PE Thompson, JK Holien, ... Molecular pharmacology 78 (4), 600-607, 2010 | 28 | 2010 |
Extracellular loops 2 and 3 of the calcitonin receptor selectively modify agonist binding and efficacy E Dal Maso, Y Zhu, V Pham, CA Reynolds, G Deganutti, CA Hick, D Yang, ... Biochemical Pharmacology 150, 214-244, 2018 | 27 | 2018 |
Mu and delta opioid receptors are coexpressed and functionally interact in the enteric nervous system of the mouse colon JJ DiCello, SE Carbone, A Saito, P Rajasekhar, RA Ceredig, V Pham, ... Cellular and molecular gastroenterology and hepatology 9 (3), 465-483, 2020 | 26 | 2020 |
Insulin-regulated aminopeptidase deficiency provides protection against ischemic stroke in mice V Pham, AL Albiston, CE Downes, CHY Wong, S Diwakarla, L Ng, S Lee, ... Journal of neurotrauma 29 (6), 1243-1248, 2012 | 25 | 2012 |
Reproduction and maternal behavior in insulin-regulated aminopeptidase (IRAP) knockout mice V Pham, P Burns, AL Albiston, HR Yeatman, L Ng, S Diwakarla, SY Chai Peptides 30 (10), 1861-1865, 2009 | 24 | 2009 |
Photoaffinity scanning in the mapping of the peptide receptor interface of class II G protein—coupled receptors VI Pham, PM Sexton Journal of Peptide Science: An Official Publication of the European Peptide …, 2004 | 24 | 2004 |
Structural basis of efficacy-driven ligand selectivity at GPCRs AS Powers, V Pham, WAC Burger, G Thompson, Y Laloudakis, ... Nature Chemical Biology 19 (7), 805-814, 2023 | 21 | 2023 |
Cannula implantation into the lateral ventricle does not adversely affect recognition or spatial working memory B Seyer, V Pham, AL Albiston, SY Chai Neuroscience Letters 628, 171-178, 2016 | 21 | 2016 |