| Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes R Karki, BR Sharma, S Tuladhar, EP Williams, L Zalduondo, P Samir, ... Cell 184 (1), 149-168. e17, 2021 | 1131 | 2021 |
| DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome P Samir, S Kesavardhana, DM Patmore, S Gingras, RKS Malireddi, ... Nature 573 (7775), 590-594, 2019 | 293 | 2019 |
| Identification of the PANoptosome: a molecular platform triggering pyroptosis, apoptosis, and necroptosis (PANoptosis) S Christgen, M Zheng, S Kesavardhana, R Karki, RK Malireddi, B Banoth, ... Frontiers in cellular and infection microbiology 10, 237, 2020 | 266 | 2020 |
| The PANoptosome: A deadly protein complex driving pyroptosis, apoptosis, and necroptosis (PANoptosis) P Samir, RK Malireddi, TD Kanneganti Frontiers in Cellular and Infection Microbiology 10, 238, 2020 | 246 | 2020 |
| Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity–independent pyroptosis, apoptosis, necroptosis, and inflammatory disease RK Malireddi, P Gurung, S Kesavardhana, P Samir, A Burton, ... Journal of Experimental Medicine 217 (3), 2020 | 211 | 2020 |
| ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis R Karki, B Sundaram, BR Sharma, SJ Lee, RKS Malireddi, LN Nguyen, ... Cell reports 37 (3), 2021 | 174 | 2021 |
| IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation R Karki, D Place, P Samir, J Mavuluri, BR Sharma, A Balakrishnan, ... Cell 173 (4), 920-933. e13, 2018 | 160 | 2018 |
| Interferon regulatory factor 1 regulates PANoptosis to prevent colorectal cancer R Karki, BR Sharma, B Banoth, RKS Malireddi, P Samir, S Tuladhar, ... JCI insight 5 (12), 2020 | 150 | 2020 |
| ZBP1/DAI ubiquitination and sensing of influenza vRNPs activate programmed cell death S Kesavardhana, T Kuriakose, CS Guy, P Samir, RKS Malireddi, A Mishra, ... Journal of Experimental Medicine 214 (8), 2217-2229, 2017 | 140 | 2017 |
| Inflammatory Cell Death, PANoptosis, Mediated by Cytokines in Diverse Cancer Lineages Inhibits Tumor Growth RKS Malireddi, R Karki, B Sundaram, B Kancharana, SJ Lee, P Samir, ... ImmunoHorizons 5 (7), 568-580, 2021 | 100 | 2021 |
| Galactosaminogalactan activates the inflammasome to provide host protection B Briard, T Fontaine, P Samir, DE Place, L Muszkieta, RKS Malireddi, ... Nature 588 (7839), 688-692, 2020 | 86 | 2020 |
| A cell-based systems biology assessment of human blood to monitor immune responses after influenza vaccination KL Hoek, P Samir, LM Howard, X Niu, N Prasad, A Galassie, Q Liu, ... PloS one 10 (2), e0118528, 2015 | 86 | 2015 |
| Cell-based systems biology analysis of human AS03-adjuvanted H5N1 avian influenza vaccine responses: a phase I randomized controlled trial LM Howard, KL Hoek, JB Goll, P Samir, A Galassie, TM Allos, X Niu, ... PLoS One 12 (1), e0167488, 2017 | 58 | 2017 |
| Analyzing the cryptome: uncovering secret sequences P Samir, AJ Link The AAPS journal 13 (2), 152-158, 2011 | 46 | 2011 |
| Identification of Changing Ribosome Protein Compositions using Mass Spectrometry P Samir, CM Browne, M Sun, B Shen, W Li, J Frank, AJ Link Proteomics 18 (20), 1800217, 2018 | 41* | 2018 |
| Saccharomyces cerevisiae Gis2 interacts with the translation machinery and is orthogonal to myotonic dystrophy type 2 protein ZNF9 MA Sammons, P Samir, AJ Link Biochemical and biophysical research communications 406 (1), 13-19, 2011 | 41 | 2011 |
| DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response S Kesavardhana, P Samir, M Zheng, RKS Malireddi, R Karki, BR Sharma, ... Journal of Biological Chemistry 296, 100579, 2021 | 38 | 2021 |
| Cutting Edge: Dysregulated CARD9 Signaling in Neutrophils Drives Inflammation in a Mouse Model of Neutrophilic Dermatoses S Tartey, P Gurung, P Samir, A Burton, TD Kanneganti The Journal of Immunology 201 (6), 1639-1644, 2018 | 28 | 2018 |
| ASK Family Kinases Are Required for Optimal NLRP3 Inflammasome Priming DE Place, P Samir, R Karki, B Briard, P Vogel, TD Kanneganti The American journal of pathology 188 (4), 1021-1030, 2018 | 21 | 2018 |
| Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion DE Place, B Briard, P Samir, R Karki, A Bhattacharya, CS Guy, JL Peters, ... PLOS Pathogens 16 (3), e1008364, 2020 | 18 | 2020 |
Thirumala-Devi KannegantiSt. Jude Children's Research HospitalVerified email at stjude.org
