| Flipping the dogma–phosphatidylserine in non-apoptotic cell death I Shlomovitz, M Speir, M Gerlic Cell Communication and Signaling 17, 1-12, 2019 | 149 | 2019 |
| Mitochondrial dysfunction caused by outer membrane vesicles from Gram-negative bacteria activates intrinsic apoptosis and inflammation P Deo, SH Chow, ML Han, M Speir, C Huang, RB Schittenhelm, S Dhital, ... Nature microbiology 5 (11), 1418-1427, 2020 | 118 | 2020 |
| Necroptosis directly induces the release of full‐length biologically active IL‐33 in vitro and in an inflammatory disease model I Shlomovitz, Z Erlich, M Speir, S Zargarian, N Baram, M Engler, ... The FEBS journal 286 (3), 507-522, 2019 | 81 | 2019 |
| The pseudokinase MLKL activates PAD4-dependent NET formation in necroptotic neutrophils AA D’Cruz, M Speir, M Bliss-Moreau, S Dietrich, S Wang, AA Chen, ... Science signaling 11 (546), eaao1716, 2018 | 75 | 2018 |
| Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis M Speir, KE Lawlor, SP Glaser, G Abraham, S Chow, A Vogrin, ... Nature microbiology 1 (3), 1-9, 2016 | 75 | 2016 |
| Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway DS Simpson, J Pang, A Weir, IY Kong, M Fritsch, M Rashidi, JP Cooney, ... Immunity 55 (3), 423-441. e9, 2022 | 71 | 2022 |
| RIP-roaring inflammation: RIPK1 and RIPK3 driven NLRP3 inflammasome activation and autoinflammatory disease M Speir, KE Lawlor Seminars in Cell & Developmental Biology 109, 114-124, 2021 | 48 | 2021 |
| Antibiotic regimen based on population analysis of residing persister cells eradicates Staphylococcus epidermidis biofilms S Yang, ID Hay, DR Cameron, M Speir, B Cui, F Su, AY Peleg, T Lithgow, ... Scientific Reports 5 (1), 18578, 2015 | 42 | 2015 |
| Ptpn6 inhibits caspase-8-and Ripk3/Mlkl-dependent inflammation M Speir, CJ Nowell, AA Chen, JA O’Donnell, IS Shamie, PR Lakin, ... Nature immunology 21 (1), 54-64, 2020 | 39 | 2020 |
| Glycolipid-peptide conjugate vaccines enhance CD8+ T cell responses against human viral proteins M Speir, A Authier-Hall, CR Brooks, KJ Farrand, BJ Compton, ... Scientific reports 7 (1), 14273, 2017 | 24 | 2017 |
| Legionella pneumophila Strain 130b Evades Macrophage Cell Death Independent of the Effector SidF in the Absence of Flagellin M Speir, A Vogrin, A Seidi, G Abraham, S Hunot, Q Han, GW Dorn, ... Frontiers in cellular and infection microbiology 7, 35, 2017 | 22 | 2017 |
| Targeting RIP kinases in chronic inflammatory disease M Speir, TM Djajawi, SA Conos, H Tye, KE Lawlor Biomolecules 11 (5), 646, 2021 | 20 | 2021 |
| Engaging natural killer T cells as ‘Universal Helpers’ for vaccination M Speir, IF Hermans, R Weinkove Drugs 77 (1), 1-15, 2017 | 20 | 2017 |
| Enhancing T cell responses and tumour immunity by vaccination with peptides conjugated to a weak NKT cell agonist BJ Compton, KJ Farrand, C Tang, TL Osmond, M Speir, A Authier-Hall, ... Organic & Biomolecular Chemistry 17 (5), 1225-1237, 2019 | 19 | 2019 |
| Programmed cell death in Legionella infection M Speir, JE Vince, T Naderer Future Microbiology 9 (1), 107-118, 2014 | 14 | 2014 |
| Candida auris uses metabolic strategies to escape and kill macrophages while avoiding robust activation of the NLRP3 inflammasome response H Weerasinghe, C Simm, TM Djajawi, I Tedja, TL Lo, DS Simpson, ... Cell Reports 42 (5), 2023 | 9 | 2023 |
| Mitochondrial dysfunction caused by outer membrane vesicles from gram‑negative bacteria activates intrinsic apoptosis and inflammation. Nat Microbiol. 2020; 5: 1418–27 P Deo, SH Chow, ML Han, M Speir, C Huang, RB Schittenhelm, S Dhital, ... DOI: https://doi. org/10.1038/s41564-020-0773-2, 1418-1427, 0 | 7 | |
| NET formation is a default epigenetic program controlled by PAD4 in apoptotic neutrophils YP Zhu, M Speir, ZH Tan, JC Lee, CJ Nowell, AA Chen, H Amatullah, ... Science Advances 9 (51), eadj1397, 2023 | 1 | 2023 |
| A1 is induced by pathogen ligands to limit myeloid cell death and NLRP3 inflammasome activation M Speir, H Tye, TA Gottschalk, DS Simpson, TM Djajawi, P Deo, ... EMBO reports 24 (11), e56865, 2023 | | 2023 |
| The Australasian Cell Death Society (ACDS): celebrating 50 years of Australasian cell death research M Speir, AH Chan, DS Simpson, T Khan, TL Saunders, IKH Poon, ... Immunology and Cell Biology 100 (1), 9-14, 2022 | | 2022 |
Kate E LawlorGroup Head, Cell Death and Inflammatory Signalling, Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research and Adjunct Research Fellow, Department of Molecular and Translational Science, Monash UniversityVerified email at hudson.org.au
