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Dana Vuzman
Dana Vuzman
Harvard Medical School, Broad Institute, Brigham and Women's Hospital
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Year
Whole-genome sequence variation, population structure and demographic history of the Dutch population
Nature genetics 46 (8), 818-825, 2014
7092014
Double-hybrid functionals for thermochemical kinetics
A Tarnopolsky, A Karton, R Sertchook, D Vuzman, JML Martin
The Journal of Physical Chemistry A 112 (1), 3-8, 2008
2552008
Intrinsically disordered regions as affinity tuners in protein–DNA interactions
D Vuzman, Y Levy
Molecular BioSystems 8 (1), 47-57, 2012
2162012
Searching DNA via a “Monkey Bar” mechanism: the significance of disordered tails
D Vuzman, A Azia, Y Levy
Journal of molecular biology 396 (3), 674-684, 2010
1792010
Loss of function mutation in LOX causes thoracic aortic aneurysm and dissection in humans
VS Lee, CM Halabi, EP Hoffman, N Carmichael, I Leshchiner, CG Lian, ...
Proceedings of the National Academy of Sciences 113 (31), 8759-8764, 2016
1672016
DNA search efficiency is modulated by charge composition and distribution in the intrinsically disordered tail
D Vuzman, Y Levy
Proceedings of the National Academy of Sciences 107 (49), 21004-21009, 2010
1302010
Asymmetrical roles of zinc fingers in dynamic DNA-scanning process by the inducible transcription factor Egr-1
L Zandarashvili, D Vuzman, A Esadze, Y Takayama, D Sahu, Y Levy, ...
Proceedings of the National Academy of Sciences 109 (26), E1724-E1732, 2012
1142012
Balancing between affinity and speed in target DNA search by zinc-finger proteins via modulation of dynamic conformational ensemble
L Zandarashvili, A Esadze, D Vuzman, CA Kemme, Y Levy, J Iwahara
Proceedings of the National Academy of Sciences 112 (37), E5142-E5149, 2015
1022015
Cationic, neutral, and anionic platinum (II) complexes based on an electron-rich PNN ligand. New modes of reactivity based on pincer hemilability and dearomatization
D Vuzman, E Poverenov, LJW Shimon, Y Diskin-Posner, D Milstein
Organometallics 27 (11), 2627-2634, 2008
772008
Facilitated DNA search by multidomain transcription factors: cross talk via a flexible linker
D Vuzman, M Polonsky, Y Levy
Biophysical Journal 99 (4), 1202-1211, 2010
762010
Actionable gene-based classification toward precision medicine in gastric cancer
H Ichikawa, M Nagahashi, Y Shimada, T Hanyu, T Ishikawa, ...
Genome medicine 9, 1-12, 2017
682017
Dual MAPK inhibition is an effective therapeutic strategy for a subset of class II BRAF mutant melanomas
M Dankner, M Lajoie, D Moldoveanu, TT Nguyen, P Savage, S Rajkumar, ...
Clinical Cancer Research 24 (24), 6483-6494, 2018
672018
Modulating protein–DNA interactions by post-translational modifications at disordered regions
D Vuzman, Y Hoffman, Y Levy
Biocomputing 2012, 188-199, 2012
332012
A framework for the detection of de novo mutations in family-based sequencing data
LC Francioli, M Cretu-Stancu, KV Garimella, M Fromer, WP Kloosterman, ...
European Journal of Human Genetics 25 (2), 227-233, 2017
292017
Brigham Genomic Medicine; Mecham, RP; et al. Loss of function mutation in LOX causes thoracic aortic aneurysm and dissection in humans
VS Lee, CM Halabi, EP Hoffman, N Carmichael, I Leshchiner, CG Lian, ...
Proc. Natl. Acad. Sci. USA 113, 8759-8764, 2016
272016
An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery
A Haghighi, JB Krier, A Toth-Petroczy, CA Cassa, NY Frank, ...
NPJ genomic medicine 3 (1), 21, 2018
242018
Reactivity and stability of platinum (II) formyl complexes based on PCP-type ligands. The significance of sterics
D Vuzman, E Poverenov, Y Diskin-Posner, G Leitus, LJW Shimon, ...
Dalton Transactions, 5692-5700, 2007
242007
The “Monkey‐Bar” Mechanism for Searching for the DNA Target Site: The Molecular Determinants
D Vuzman, Y Levy
Israel Journal of Chemistry 54 (8‐9), 1374-1381, 2014
232014
Variants in STXBP3 are Associated with Very Early Onset Inflammatory Bowel Disease, Bilateral Sensorineural Hearing Loss and Immune Dysregulation
J Ouahed, JR Kelsen, WA Spessott, K Kooshesh, ML Sanmillan, ...
Journal of Crohn's and Colitis 15 (11), 1908-1919, 2021
132021
Moving genomics to routine care: an initial pilot in acute cardiovascular disease
Z Aryan, A Szanto, A Pantazi, T Reddi, C Rheinstein, W Powers, E Wilson, ...
Circulation: Genomic and Precision Medicine 13 (5), 406-416, 2020
132020
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