Whole-genome sequence variation, population structure and demographic history of the Dutch population Nature genetics 46 (8), 818-825, 2014 | 709 | 2014 |
Double-hybrid functionals for thermochemical kinetics A Tarnopolsky, A Karton, R Sertchook, D Vuzman, JML Martin The Journal of Physical Chemistry A 112 (1), 3-8, 2008 | 255 | 2008 |
Intrinsically disordered regions as affinity tuners in protein–DNA interactions D Vuzman, Y Levy Molecular BioSystems 8 (1), 47-57, 2012 | 216 | 2012 |
Searching DNA via a “Monkey Bar” mechanism: the significance of disordered tails D Vuzman, A Azia, Y Levy Journal of molecular biology 396 (3), 674-684, 2010 | 179 | 2010 |
Loss of function mutation in LOX causes thoracic aortic aneurysm and dissection in humans VS Lee, CM Halabi, EP Hoffman, N Carmichael, I Leshchiner, CG Lian, ... Proceedings of the National Academy of Sciences 113 (31), 8759-8764, 2016 | 167 | 2016 |
DNA search efficiency is modulated by charge composition and distribution in the intrinsically disordered tail D Vuzman, Y Levy Proceedings of the National Academy of Sciences 107 (49), 21004-21009, 2010 | 130 | 2010 |
Asymmetrical roles of zinc fingers in dynamic DNA-scanning process by the inducible transcription factor Egr-1 L Zandarashvili, D Vuzman, A Esadze, Y Takayama, D Sahu, Y Levy, ... Proceedings of the National Academy of Sciences 109 (26), E1724-E1732, 2012 | 114 | 2012 |
Balancing between affinity and speed in target DNA search by zinc-finger proteins via modulation of dynamic conformational ensemble L Zandarashvili, A Esadze, D Vuzman, CA Kemme, Y Levy, J Iwahara Proceedings of the National Academy of Sciences 112 (37), E5142-E5149, 2015 | 102 | 2015 |
Cationic, neutral, and anionic platinum (II) complexes based on an electron-rich PNN ligand. New modes of reactivity based on pincer hemilability and dearomatization D Vuzman, E Poverenov, LJW Shimon, Y Diskin-Posner, D Milstein Organometallics 27 (11), 2627-2634, 2008 | 77 | 2008 |
Facilitated DNA search by multidomain transcription factors: cross talk via a flexible linker D Vuzman, M Polonsky, Y Levy Biophysical Journal 99 (4), 1202-1211, 2010 | 76 | 2010 |
Actionable gene-based classification toward precision medicine in gastric cancer H Ichikawa, M Nagahashi, Y Shimada, T Hanyu, T Ishikawa, ... Genome medicine 9, 1-12, 2017 | 68 | 2017 |
Dual MAPK inhibition is an effective therapeutic strategy for a subset of class II BRAF mutant melanomas M Dankner, M Lajoie, D Moldoveanu, TT Nguyen, P Savage, S Rajkumar, ... Clinical Cancer Research 24 (24), 6483-6494, 2018 | 67 | 2018 |
Modulating protein–DNA interactions by post-translational modifications at disordered regions D Vuzman, Y Hoffman, Y Levy Biocomputing 2012, 188-199, 2012 | 33 | 2012 |
A framework for the detection of de novo mutations in family-based sequencing data LC Francioli, M Cretu-Stancu, KV Garimella, M Fromer, WP Kloosterman, ... European Journal of Human Genetics 25 (2), 227-233, 2017 | 29 | 2017 |
Brigham Genomic Medicine; Mecham, RP; et al. Loss of function mutation in LOX causes thoracic aortic aneurysm and dissection in humans VS Lee, CM Halabi, EP Hoffman, N Carmichael, I Leshchiner, CG Lian, ... Proc. Natl. Acad. Sci. USA 113, 8759-8764, 2016 | 27 | 2016 |
An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery A Haghighi, JB Krier, A Toth-Petroczy, CA Cassa, NY Frank, ... NPJ genomic medicine 3 (1), 21, 2018 | 24 | 2018 |
Reactivity and stability of platinum (II) formyl complexes based on PCP-type ligands. The significance of sterics D Vuzman, E Poverenov, Y Diskin-Posner, G Leitus, LJW Shimon, ... Dalton Transactions, 5692-5700, 2007 | 24 | 2007 |
The “Monkey‐Bar” Mechanism for Searching for the DNA Target Site: The Molecular Determinants D Vuzman, Y Levy Israel Journal of Chemistry 54 (8‐9), 1374-1381, 2014 | 23 | 2014 |
Variants in STXBP3 are Associated with Very Early Onset Inflammatory Bowel Disease, Bilateral Sensorineural Hearing Loss and Immune Dysregulation J Ouahed, JR Kelsen, WA Spessott, K Kooshesh, ML Sanmillan, ... Journal of Crohn's and Colitis 15 (11), 1908-1919, 2021 | 13 | 2021 |
Moving genomics to routine care: an initial pilot in acute cardiovascular disease Z Aryan, A Szanto, A Pantazi, T Reddi, C Rheinstein, W Powers, E Wilson, ... Circulation: Genomic and Precision Medicine 13 (5), 406-416, 2020 | 13 | 2020 |