Focal adhesion kinase: in command and control of cell motility SK Mitra, DA Hanson, DD Schlaepfer Nature reviews Molecular cell biology 6 (1), 56-68, 2005 | 3072 | 2005 |
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase DD Schlaepfer, SK Hanks, T Hunter, P Geer Nature 372 (6508), 786-791, 1994 | 2101 | 1994 |
Integrin-regulated FAK–Src signaling in normal and cancer cells SK Mitra, DD Schlaepfer Current opinion in cell biology 18 (5), 516-523, 2006 | 1787 | 2006 |
FAK integrates growth-factor and integrin signals to promote cell migration DJ Sieg, CR Hauck, D Ilic, CK Klingbeil, E Schaefer, CH Damsky, ... Nature cell biology 2 (5), 249-256, 2000 | 1541 | 2000 |
Signaling through focal adhesion kinase DD Schlaepfer, CR Hauck, DJ Sieg Progress in biophysics and molecular biology 71 (3-4), 435-478, 1999 | 1522 | 1999 |
FAK in cancer: mechanistic findings and clinical applications FJ Sulzmaier, C Jean, DD Schlaepfer Nature reviews cancer 14 (9), 598-610, 2014 | 1299 | 2014 |
Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration DJ Sieg, CR Hauck, DD Schlaepfer Journal of cell science 112 (16), 2677-2691, 1999 | 885 | 1999 |
Differential regulation of cell motility and invasion by FAK DA Hsia, SK Mitra, CR Hauck, DN Streblow, JA Nelson, D Ilic, S Huang, ... The Journal of cell biology 160 (5), 753-767, 2003 | 724 | 2003 |
Integrin signalling and tyrosine phosphorylation: just the FAKs? DD Schlaepfer, T Hunter Trends in cell biology 8 (4), 151-157, 1998 | 689 | 1998 |
Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation AM Pasapera, IC Schneider, E Rericha, DD Schlaepfer, CM Waterman Journal of Cell Biology 188 (6), 877-890, 2010 | 645 | 2010 |
Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis D Ilić, EAC Almeida, DD Schlaepfer, P Dazin, S Aizawa, CH Damsky The Journal of cell biology 143 (2), 547-560, 1998 | 611 | 1998 |
Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases DD Schlaepfer, T Hunter Molecular and cellular biology, 1996 | 611 | 1996 |
Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover XD Ren, WB Kiosses, DJ Sieg, CA Otey, DD Schlaepfer, MA Schwartz Journal of cell science 113 (20), 3673-3678, 2000 | 606 | 2000 |
Control of motile and invasive cell phenotypes by focal adhesion kinase DD Schlaepfer, SK Mitra, D Ilic Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1692 (2-3), 77-102, 2004 | 603 | 2004 |
Fibronectin-stimulated signaling from a focal adhesion kinase–c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins DD Schlaepfer, MA Broome, T Hunter Molecular and cellular biology, 1997 | 586 | 1997 |
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression H Laklai, YA Miroshnikova, MW Pickup, EA Collisson, GE Kim, AS Barrett, ... Nature medicine 22 (5), 497-505, 2016 | 557 | 2016 |
Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation ST Lim, XL Chen, Y Lim, DA Hanson, TT Vo, K Howerton, N Larocque, ... Molecular cell 29 (1), 9-22, 2008 | 551 | 2008 |
Multiple connections link FAK to cell motility and invasion DD Schlaepfer, SK Mitra Current opinion in genetics & development 14 (1), 92-101, 2004 | 547 | 2004 |
Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src-and focal adhesion kinase-initiated tyrosine … DD Schlaepfer, KC Jones, T Hunter Molecular and cellular biology 18 (5), 2571-2585, 1998 | 535 | 1998 |
Fluid shear stress activation of focal adhesion kinase: linking to mitogen-activated protein kinases S Li, M Kim, YL Hu, S Jalali, DD Schlaepfer, T Hunter, S Chien, JYJ Shyy Journal of Biological Chemistry 272 (48), 30455-30462, 1997 | 532 | 1997 |