Follow
David Schlaepfer
David Schlaepfer
Moores UCSD Cancer Center
Verified email at ucsd.edu - Homepage
Title
Cited by
Cited by
Year
Focal adhesion kinase: in command and control of cell motility
SK Mitra, DA Hanson, DD Schlaepfer
Nature reviews Molecular cell biology 6 (1), 56-68, 2005
30662005
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
DD Schlaepfer, SK Hanks, T Hunter, P Geer
Nature 372 (6508), 786-791, 1994
21011994
Integrin-regulated FAK–Src signaling in normal and cancer cells
SK Mitra, DD Schlaepfer
Current opinion in cell biology 18 (5), 516-523, 2006
17822006
FAK integrates growth-factor and integrin signals to promote cell migration
DJ Sieg, CR Hauck, D Ilic, CK Klingbeil, E Schaefer, CH Damsky, ...
Nature cell biology 2 (5), 249-256, 2000
15402000
Signaling through focal adhesion kinase
DD Schlaepfer, CR Hauck, DJ Sieg
Progress in biophysics and molecular biology 71 (3-4), 435-478, 1999
15221999
FAK in cancer: mechanistic findings and clinical applications
FJ Sulzmaier, C Jean, DD Schlaepfer
Nature reviews cancer 14 (9), 598-610, 2014
12972014
Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration
DJ Sieg, CR Hauck, DD Schlaepfer
Journal of cell science 112 (16), 2677-2691, 1999
8841999
Differential regulation of cell motility and invasion by FAK
DA Hsia, SK Mitra, CR Hauck, DN Streblow, JA Nelson, D Ilic, S Huang, ...
The Journal of cell biology 160 (5), 753-767, 2003
7242003
Integrin signalling and tyrosine phosphorylation: just the FAKs?
DD Schlaepfer, T Hunter
Trends in cell biology 8 (4), 151-157, 1998
6891998
Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation
AM Pasapera, IC Schneider, E Rericha, DD Schlaepfer, CM Waterman
Journal of Cell Biology 188 (6), 877-890, 2010
6402010
Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis
D Ilić, EAC Almeida, DD Schlaepfer, P Dazin, S Aizawa, CH Damsky
The Journal of cell biology 143 (2), 547-560, 1998
6111998
Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases
DD Schlaepfer, T Hunter
Molecular and cellular biology, 1996
6111996
Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover
XD Ren, WB Kiosses, DJ Sieg, CA Otey, DD Schlaepfer, MA Schwartz
Journal of cell science 113 (20), 3673-3678, 2000
6062000
Control of motile and invasive cell phenotypes by focal adhesion kinase
DD Schlaepfer, SK Mitra, D Ilic
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1692 (2-3), 77-102, 2004
6022004
Fibronectin-stimulated signaling from a focal adhesion kinase–c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins
DD Schlaepfer, MA Broome, T Hunter
Molecular and cellular biology, 1997
5861997
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression
H Laklai, YA Miroshnikova, MW Pickup, EA Collisson, GE Kim, AS Barrett, ...
Nature medicine 22 (5), 497-505, 2016
5502016
Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation
ST Lim, XL Chen, Y Lim, DA Hanson, TT Vo, K Howerton, N Larocque, ...
Molecular cell 29 (1), 9-22, 2008
5502008
Multiple connections link FAK to cell motility and invasion
DD Schlaepfer, SK Mitra
Current opinion in genetics & development 14 (1), 92-101, 2004
5472004
Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src-and focal adhesion kinase-initiated tyrosine …
DD Schlaepfer, KC Jones, T Hunter
Molecular and cellular biology 18 (5), 2571-2585, 1998
5351998
Fluid shear stress activation of focal adhesion kinase: linking to mitogen-activated protein kinases
S Li, M Kim, YL Hu, S Jalali, DD Schlaepfer, T Hunter, S Chien, JYJ Shyy
Journal of Biological Chemistry 272 (48), 30455-30462, 1997
5321997
The system can't perform the operation now. Try again later.
Articles 1–20