The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCFβ-TrCP E3 ligase CY Liu, ZY Zha, X Zhou, H Zhang, W Huang, D Zhao, T Li, SW Chan, ... Journal of Biological Chemistry 285 (48), 37159-37169, 2010 | 573 | 2010 |
A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells SW Chan, CJ Lim, K Guo, CP Ng, I Lee, W Hunziker, Q Zeng, W Hong Cancer research 68 (8), 2592-2598, 2008 | 544 | 2008 |
Interaction between tumour-infiltrating B cells and T cells controls the progression of hepatocellular carcinoma M Garnelo, A Tan, Z Her, J Yeong, CJ Lim, J Chen, KH Lim, A Weber, ... Gut 66 (2), 342-351, 2017 | 417 | 2017 |
Hippo pathway-independent restriction of TAZ and YAP by angiomotin SW Chan, CJ Lim, YF Chong, AV Pobbati, C Huang, W Hong Journal of Biological Chemistry 286 (9), 7018-7026, 2011 | 409 | 2011 |
Multidimensional analyses reveal distinct immune microenvironment in hepatitis B virus-related hepatocellular carcinoma CJ Lim, YH Lee, L Pan, L Lai, C Chua, M Wasser, TKH Lim, J Yeong, ... Gut 68 (5), 916-927, 2019 | 270 | 2019 |
TEADs mediate nuclear retention of TAZ to promote oncogenic transformation SW Chan, CJ Lim, LS Loo, YF Chong, C Huang, W Hong Journal of Biological Chemistry 284 (21), 14347-14358, 2009 | 261 | 2009 |
Structural basis of YAP recognition by TEAD4 in the hippo pathway L Chen, SW Chan, XQ Zhang, M Walsh, CJ Lim, W Hong, H Song Genes & development 24 (3), 290-300, 2010 | 246 | 2010 |
Delineation of an immunosuppressive gradient in hepatocellular carcinoma using high-dimensional proteomic and transcriptomic analyses V Chew, L Lai, L Pan, CJ Lim, J Li, R Ong, C Chua, JY Leong, KH Lim, ... Proceedings of the National Academy of Sciences 114 (29), E5900-E5909, 2017 | 201 | 2017 |
The Hippo pathway in biological control and cancer development SW Chan, CJ Lim, L Chen, YF Chong, C Huang, H Song, W Hong Journal of cellular physiology 226 (4), 928-939, 2011 | 193 | 2011 |
Immune activation underlies a sustained clinical response to Yttrium-90 radioembolisation in hepatocellular carcinoma V Chew, YH Lee, L Pan, NJM Nasir, CJ Lim, C Chua, L Lai, SN Hazirah, ... Gut 68 (2), 335-346, 2019 | 181 | 2019 |
Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Y Li, H Zhou, F Li, SW Chan, Z Lin, Z Wei, Z Yang, F Guo, CJ Lim, W Xing, ... Cell research 25 (7), 801-817, 2015 | 163 | 2015 |
WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ SW Chan, CJ Lim, C Huang, YF Chong, HJ Gunaratne, KA Hogue, ... Oncogene 30 (5), 600, 2011 | 112 | 2011 |
Actin-binding and cell proliferation activities of angiomotin family members are regulated by Hippo pathway-mediated phosphorylation SW Chan, CJ Lim, F Guo, I Tan, T Leung, W Hong Journal of Biological Chemistry 288 (52), 37296-37307, 2013 | 106 | 2013 |
Crystal structure of TAZ-TEAD complex reveals a distinct interaction mode from that of YAP-TEAD complex HYK Kaan, SW Chan, SKJ Tan, F Guo, CJ Lim, W Hong, H Song scientific reports 7 (1), 1-11, 2017 | 104 | 2017 |
Intratumoural immune heterogeneity as a hallmark of tumour evolution and progression in hepatocellular carcinoma P Nguyen, S Ma, C Phua, K Neslihan, H Lai, CJ Lim, JQ Lim, L Lai, ... | 94 | 2020 |
Hypoxia‐driven immunosuppression by Treg and type‐2 conventional dendritic cells in hepatocellular carcinoma SDO Suthen, CJ Lim, PHD Nguyen, CA Dutertre, HLH Lai, M Wasser, ... Hepatology, 2022 | 82 | 2022 |
An automated staining protocol for seven-colour immunofluorescence of human tissue sections for diagnostic and prognostic use JCT Lim, JPS Yeong, CJ Lim, CCH Ong, SC Wong, VSP Chew, ... Pathology 50 (3), 333-341, 2018 | 74 | 2018 |
Expression of CD38 on macrophages predicts improved prognosis in hepatocellular carcinoma JH Lam, HHM Ng, CJ Lim, XN Sim, F Malavasi, H Li, JJH Loh, K Sabai, ... Frontiers in immunology 10, 2093, 2019 | 58 | 2019 |
Uncoupling immune trajectories of response and adverse events from anti-PD-1 immunotherapy in hepatocellular carcinoma S Chuah, J Lee, Y Song, HD Kim, M Wasser, NA Kaya, K Bang, YJ Lee, ... Journal of Hepatology, 2022 | 47 | 2022 |
Immunological hallmarks for clinical response to BCG in bladder cancer CJ Lim, PHD Nguyen, M Wasser, P Kumar, Y Lee, NJM Nasir, C Chua, ... Frontiers in Immunology 11, 3634, 2020 | 40 | 2020 |