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Michael Lovette
Michael Lovette
Amgen
Verified email at merck.com
Title
Cited by
Cited by
Year
Crystal shape engineering
MA Lovette, AR Browning, DW Griffin, JP Sizemore, RC Snyder, ...
Industrial & engineering chemistry research 47 (24), 9812-9833, 2008
3642008
Needle-shaped crystals: causality and solvent selection guidance based on periodic bond chains
MA Lovette, MF Doherty
Crystal growth & design 13 (8), 3341-3352, 2013
992013
Predictive modeling of supersaturation-dependent crystal shapes
MA Lovette, MF Doherty
Crystal growth & design 12 (2), 656-669, 2012
902012
Perspectives on the current state, challenges, and opportunities in pharmaceutical crystallization process development
A Cote, D Erdemir, KP Girard, DA Green, MA Lovette, E Sirota, NK Nere
Crystal Growth & Design 20 (12), 7568-7581, 2020
652020
Crystal shape modification through cycles of dissolution and growth: Attainable regions and experimental validation
MA Lovette, M Muratore, MF Doherty
AIChE Journal 58 (5), 1465-1474, 2011
642011
Multisite models to determine the distribution of kink sites adjacent to low-energy edges
MA Lovette, MF Doherty
Physical Review E 85 (2), 021604, 2012
262012
Kink rate model for the general case of organic molecular crystals
SH Kim, P Dandekar, MA Lovette, MF Doherty
Crystal growth & design 14 (5), 2460-2467, 2014
242014
Continuous process improvement in the manufacture of Carfilzomib, part 2: an improved process for synthesis of the Epoxyketone warhead
MG Beaver, X Shi, J Riedel, P Patel, A Zeng, MT Corbett, JA Robinson, ...
Organic Process Research & Development 24 (4), 490-499, 2020
222020
Reinterpreting edge energies calculated from crystal growth experiments
MA Lovette, MF Doherty
Journal of crystal growth 327 (1), 117-126, 2011
182011
Axial chirality in the sotorasib drug substance, Part 1: Development of a classical resolution to prepare an atropisomerically pure sotorasib intermediate
AT Parsons, S Caille, MA Caporini, DJ Griffin, MA Lovette, W Powazinik IV, ...
Organic Process Research & Development 26 (9), 2629-2635, 2022
162022
Development of a Commercial Manufacturing Process for Sotorasib, a First-in-Class KRASG12C Inhibitor
L Zhang, DJ Griffin, MG Beaver, LE Blue, CJ Borths, DB Brown, S Caille, ...
Organic Process Research & Development 26 (11), 3115-3125, 2022
152022
Implementing continuous manufacturing for the final methylation step in the AMG 397 process to deliver key quality attributes
JK Tom, MM Achmatowicz, MG Beaver, J Colyer, A Ericson, TL Hwang, ...
Organic Process Research & Development 25 (3), 486-499, 2021
122021
Cross-pharma collaboration for the development of a simulation tool for the model-based digital design of pharmaceutical crystallization processes (CrySiV)
B Szilagyi, WL Wu, A Eren, J Mackey, S Kshirsagar, E Szilagyi, ...
Crystal Growth & Design 21 (11), 6448-6464, 2021
92021
Evaluation of predictive solubility models in pharmaceutical process development─ an enabling technologies consortium collaboration
MA Lovette, J Albrecht, RS Ananthula, F Ricci, R Sangodkar, MS Shah, ...
Crystal Growth & Design 22 (9), 5239-5263, 2022
52022
Chiral control of enantiomers through crystallization: Moving from ternary phase diagrams to design spaces
MA Lovette
AIChE Journal 64 (9), 3323-3331, 2018
42018
Solubility Model to Guide Solvent Selection in Synthetic Process Development
MA Lovette
Crystal Growth & Design 22 (7), 4404-4420, 2022
32022
Introduction To Chiral Crystallization In Pharmaceutical Development And Manufacturing
JE Tabora, S Brueggemeier, J Sweeney, M Lovette
Chemical Engineering in the Pharmaceutical Industry: Active Pharmaceutical …, 2019
22019
Prediction and Modification of Crystal Shapes
MA Lovette
Dissertation Abstracts International 73 (03), 2011
22011
A Continuous Process for Manufacturing Apremilast. Part I: Process Development and Intensification by Utilizing Flow Chemistry Principles
HW Hsieh, CM Cohen, DJ Griffin, P Ananthoji, NH Avci, DB Brown, ...
Organic Process Research & Development, 2024
12024
Ring Closing Synthesis of Macrocyclic MCL-1 Inhibitor Intermediates
AG Smith, JS Tedrow, STP Gabrielle, OR Thiel, L Huang, PC Roosen, ...
US Patent App. 17/922,619, 2023
2023
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