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Mandy M.T. van Leent
Mandy M.T. van Leent
Geverifieerd e-mailadres voor mountsinai.org
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Inhibiting inflammation with myeloid cell-specific nanobiologics promotes organ transplant acceptance
MS Braza, MMT van Leent, M Lameijer, BL Sanchez-Gaytan, RJW Arts, ...
Immunity 49 (5), 819-828. e6, 2018
1942018
Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates
M Lameijer, T Binderup, MMT Van Leent, ML Senders, F Fay, J Malkus, ...
Nature biomedical engineering 2 (5), 279-292, 2018
1082018
Trained immunity-promoting nanobiologic therapy suppresses tumor growth and potentiates checkpoint inhibition
B Priem, MMT van Leent, AJP Teunissen, AM Sofias, VP Mourits, ...
Cell 183 (3), 786-801. e19, 2020
1062020
Immune checkpoint inhibitor therapy aggravates T cell–driven plaque inflammation in atherosclerosis
K Poels, MMT van Leent, C Boutros, H Tissot, S Roy, AE Meerwaldt, ...
Cardio Oncology 2 (4), 599-610, 2020
862020
Tumor Targeting by αvβ3-Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking
AM Sofias, YC Toner, AE Meerwaldt, MMT van Leent, G Soultanidis, ...
ACS nano 14 (7), 7832-7846, 2020
762020
High-density lipoprotein nanobiologics for precision medicine
WJM Mulder, MMT Van Leent, M Lameijer, EA Fisher, ZA Fayad, ...
Accounts of chemical research 51 (1), 127-137, 2018
682018
Imaging-assisted nanoimmunotherapy for atherosclerosis in multiple species
T Binderup, R Duivenvoorden, F Fay, MMT van Leent, J Malkus, S Baxter, ...
Science translational medicine 11 (506), eaaw7736, 2019
602019
Regulating trained immunity with nanomedicine
MMT van Leent, B Priem, DP Schrijver, A de Dreu, SRJ Hofstraat, ...
Nature Reviews Materials 7 (6), 465-481, 2022
512022
Prosaposin mediates inflammation in atherosclerosis
MMT van Leent, TJ Beldman, YC Toner, MA Lameijer, N Rother, ...
Science translational medicine 13 (584), eabe1433, 2021
492021
Probing myeloid cell dynamics in ischaemic heart disease by nanotracer hot-spot imaging
ML Senders, AE Meerwaldt, MMT van Leent, BL Sanchez-Gaytan, ...
Nature nanotechnology 15 (5), 398-405, 2020
492020
Nanoimmunotherapy to treat ischaemic heart disease
R Duivenvoorden, ML Senders, MMT van Leent, C Pérez-Medina, ...
Nature Reviews Cardiology 16 (1), 21-32, 2019
492019
Antibody-mediated inhibition of CTLA4 aggravates atherosclerotic plaque inflammation and progression in hyperlipidemic mice
K Poels, MMT van Leent, ME Reiche, PJH Kusters, S Huveneers, ...
Cells 9 (9), 1987, 2020
482020
Imaging Cardiovascular and Lung Macrophages With the Positron Emission Tomography Sensor 64Cu-Macrin in Mice, Rabbits, and Pigs
M Nahrendorf, FF Hoyer, AE Meerwaldt, MMT van Leent, ML Senders, ...
Circulation: Cardiovascular Imaging 13 (10), e010586, 2020
382020
Hydroxychloroquine inhibits the trained innate immune response to interferons
N Rother, C Yanginlar, RGH Lindeboom, S Bekkering, MMT van Leent, ...
Cell Reports Medicine 1 (9), 2020
322020
A modular approach toward producing nanotherapeutics targeting the innate immune system
MMT van Leent, AE Meerwaldt, A Berchouchi, YC Toner, ME Burnett, ...
Science advances 7 (10), eabe7853, 2021
222021
Systematically evaluating DOTATATE and FDG as PET immuno-imaging tracers of cardiovascular inflammation
YC Toner, AA Ghotbi, S Naidu, K Sakurai, MMT van Leent, S Jordan, ...
Scientific reports 12 (1), 6185, 2022
182022
FSH-blocking therapeutic for osteoporosis
S Gera, TC Kuo, AA Gumerova, F Korkmaz, D Sant, V DeMambro, ...
Elife 11, e78022, 2022
132022
Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cells
DP Schrijver, RJ Röring, J Deckers, A de Dreu, YC Toner, G Prevot, ...
Nature Biomedical Engineering 7 (9), 1097-1112, 2023
92023
Multimodal imaging of bacterial-host interface in mice and piglets with Staphylococcus aureus endocarditis
P Panizzi, M Krohn-Grimberghe, E Keliher, YX Ye, J Grune, ...
Science translational medicine 12 (568), eaay2104, 2020
82020
Multiparametric immunoimaging maps inflammatory signatures in murine myocardial infarction models
A Maier, YC Toner, J Munitz, NAT Sullivan, K Sakurai, AE Meerwaldt, ...
Basic to Translational Science 8 (7), 801-816, 2023
62023
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