The energetics and physiological impact of cohesin extrusion L Vian, A Pękowska, SSP Rao, KR Kieffer-Kwon, S Jung, L Baranello, ... Cell 173 (5), 1165-1178. e20, 2018 | 519 | 2018 |
Transcription-dependent dynamic supercoiling is a short-range genomic force F Kouzine, A Gupta, L Baranello, D Wojtowicz, K Ben-Aissa, J Liu, ... Nature structural & molecular biology 20 (3), 396-403, 2013 | 315 | 2013 |
RNA polymerase II regulates topoisomerase 1 activity to favor efficient transcription L Baranello, D Wojtowicz, K Cui, BN Devaiah, HJ Chung, KY Chan-Salis, ... Cell 165 (2), 357-371, 2016 | 273 | 2016 |
Permanganate/S1 nuclease footprinting reveals non-B DNA structures with regulatory potential across a mammalian genome F Kouzine, D Wojtowicz, L Baranello, A Yamane, S Nelson, W Resch, ... Cell systems 4 (3), 344-356. e7, 2017 | 191 | 2017 |
Myc regulates chromatin decompaction and nuclear architecture during B cell activation KR Kieffer-Kwon, K Nimura, SSP Rao, J Xu, S Jung, A Pekowska, M Dose, ... Molecular cell 67 (4), 566-578. e10, 2017 | 190 | 2017 |
Spatial chromosome folding and active transcription drive DNA fragility and formation of oncogenic MLL translocations HJ Gothe, BAM Bouwman, EG Gusmao, R Piccinno, G Petrosino, ... Molecular cell 75 (2), 267-283. e12, 2019 | 137 | 2019 |
The importance of being supercoiled: how DNA mechanics regulate dynamic processes L Baranello, D Levens, A Gupta, F Kouzine Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1819 (7), 632-638, 2012 | 124 | 2012 |
ChIP bias as a function of cross-linking time L Baranello, F Kouzine, S Sanford, D Levens Chromosome research 24, 175-181, 2016 | 96 | 2016 |
MYC protein stability is negatively regulated by BRD4 BN Devaiah, J Mu, B Akman, S Uppal, JD Weissman, D Cheng, ... Proceedings of the National Academy of Sciences 117 (24), 13457-13467, 2020 | 93 | 2020 |
DNA break mapping reveals topoisomerase II activity genome-wide L Baranello, F Kouzine, D Wojtowicz, K Cui, TM Przytycka, K Zhao, ... International journal of molecular sciences 15 (7), 13111-13122, 2014 | 84 | 2014 |
DNA topoisomerase I inhibition by camptothecin induces escape of RNA polymerase II from promoter-proximal pause site, antisense transcription and histone acetylation at the … L Baranello, D Bertozzi, MV Fogli, Y Pommier, G Capranico Nucleic acids research 38 (1), 159-171, 2010 | 83 | 2010 |
The effects of camptothecin on RNA polymerase II transcription: roles of DNA topoisomerase I G Capranico, F Ferri, MV Fogli, A Russo, L Lotito, L Baranello Biochimie 89 (4), 482-489, 2007 | 77 | 2007 |
DNA topology and transcription F Kouzine, D Levens, L Baranello Nucleus 5 (3), 195-202, 2014 | 64 | 2014 |
Global inhibition with specific activation: how p53 and MYC redistribute the transcriptome in the DNA double-strand break response JR Porter, BE Fisher, L Baranello, JC Liu, DM Kambach, Z Nie, WS Koh, ... Molecular cell 67 (6), 1013-1025. e9, 2017 | 63 | 2017 |
GTF2E2 mutations destabilize the general transcription factor complex TFIIE in individuals with DNA repair-proficient trichothiodystrophy C Kuschal, E Botta, D Orioli, JJ Digiovanna, S Seneca, K Keymolen, ... The American Journal of Human Genetics 98 (4), 627-642, 2016 | 59 | 2016 |
Dissecting the transcriptional functions of human DNA topoisomerase I by selective inhibitors: implications for physiological and therapeutic modulation of enzyme activity G Capranico, J Marinello, L Baranello Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1806 (2), 240-250, 2010 | 54 | 2010 |
DNA Topoisomerases: Beyond the standard role L Baranello, F Kouzine, D Levens Transcription 4 (5), 232-237, 2013 | 45 | 2013 |
MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome” SK Das, V Kuzin, DP Cameron, S Sanford, RK Jha, Z Nie, MT Rosello, ... Molecular cell 82 (1), 140-158. e12, 2022 | 36 | 2022 |
Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1 HS Cascales, K Burdova, A Middleton, V Kuzin, E Müllers, H Stoy, ... Life Science Alliance 4 (3), 2021 | 33 | 2021 |
Controlling gene expression by DNA mechanics: emerging insights and challenges D Levens, L Baranello, F Kouzine Biophysical reviews 8, 259-268, 2016 | 32 | 2016 |