Cotranscriptionally formed DNA: RNA hybrids mediate transcription elongation impairment and transcription-associated recombination P Huertas, A Aguilera Molecular cell 12 (3), 711-721, 2003 | 860 | 2003 |
Human CtIP mediates cell cycle control of DNA end resection and double strand break repair P Huertas, SP Jackson Journal of Biological Chemistry 284 (14), 9558-9565, 2009 | 603 | 2009 |
CDK targets Sae2 to control DNA-end resection and homologous recombination P Huertas, F Cortés-Ledesma, AA Sartori, A Aguilera, SP Jackson Nature 455 (7213), 689-692, 2008 | 563 | 2008 |
CDK targets Sae2 to control DNA-end resection and homologous recombination P Huertas, F Cortés-Ledesma, AA Sartori, A Aguilera, SP Jackson Nature 455 (7213), 689-692, 2008 | 563 | 2008 |
DNA resection in eukaryotes: deciding how to fix the break P Huertas Nature structural & molecular biology 17 (1), 11-16, 2010 | 517 | 2010 |
BRCA1 accelerates CtIP-mediated DNA-end resection A Cruz-García, A López-Saavedra, P Huertas Cell reports 9 (2), 451-459, 2014 | 269 | 2014 |
The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability C González-Aguilera, C Tous, B Gómez-González, P Huertas, R Luna, ... Molecular biology of the cell 19 (10), 4310-4318, 2008 | 176 | 2008 |
CtIP Mutations Cause Seckel and Jawad Syndromes P Qvist, P Huertas, S Jimeno, M Nyegaard, MJ Hassan, SP Jackson, ... PLoS genetics 7 (10), e1002310, 2011 | 158 | 2011 |
Studying DNA double-strand break repair: an ever-growing toolbox AC Vítor, P Huertas, G Legube, SRF De Almeida Frontiers in molecular biosciences 7, 24, 2020 | 147 | 2020 |
Interdependence between transcription and mRNP processing and export, and its impact on genetic stability R Luna, S Jimeno, M Marín, P Huertas, M García-Rubio, A Aguilera Molecular cell 18 (6), 711-722, 2005 | 140 | 2005 |
Mitotic recombination in Saccharomyces cerevisiae F Prado, F Cortes-Ledesma, P Huertas, A Aguilera Current genetics 42, 185-198, 2003 | 115 | 2003 |
UBQLN4 represses homologous recombination and is overexpressed in aggressive tumors RD Jachimowicz, F Beleggia, J Isensee, BB Velpula, J Goergens, ... Cell 176 (3), 505-519. e22, 2019 | 110 | 2019 |
EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks J Domingo-Prim, M Endara-Coll, F Bonath, S Jimeno, R Prados-Carvajal, ... Nature communications 10 (1), 2135, 2019 | 98 | 2019 |
Recombinogenic Effects of DNA-Damaging Agents Are Synergistically Increased by Transcription in Saccharomyces cerevisiae: New Insights Into Transcription … M Garcia-Rubio, P Huertas, S Gonzalez-Barrera, A Aguilera Genetics 165 (2), 457-466, 2003 | 67 | 2003 |
Neddylation inhibits CtIP-mediated resection and regulates DNA double strand break repair pathway choice S Jimeno, MJ Fernández-Ávila, A Cruz-García, C Cepeda-García, ... Nucleic acids research 43 (2), 987-999, 2015 | 58 | 2015 |
New tools to study DNA double-strand break repair pathway choice D Gomez-Cabello, S Jimeno, MJ Fernández-Ávila, P Huertas PloS one 8 (10), e77206, 2013 | 56 | 2013 |
An hpr1 Point Mutation That Impairs Transcription and mRNP Biogenesis without Increasing Recombination P Huertas, ML García-Rubio, RE Wellinger, R Luna, A Aguilera Molecular and cellular biology 26 (20), 7451-7465, 2006 | 55 | 2006 |
The ubiquitin E3/E4 ligase UBE4A adjusts protein ubiquitylation and accumulation at sites of DNA damage, facilitating double-strand break repair K Baranes-Bachar, A Levy-Barda, J Oehler, DA Reid, I Soria-Bretones, ... Molecular cell 69 (5), 866-878. e7, 2018 | 54 | 2018 |
The helicase PIF1 facilitates resection over sequences prone to forming G4 structures S Jimeno, R Camarillo, F Mejías-Navarro, MJ Fernández-Ávila, ... Cell reports 24 (12), 3262-3273. e4, 2018 | 52 | 2018 |
The helicase PIF1 facilitates resection over sequences prone to forming G4 structures S Jimeno, R Camarillo, F Mejías-Navarro, MJ Fernández-Ávila, ... Cell reports 24 (12), 3262-3273. e4, 2018 | 52 | 2018 |