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Laia Josa Culleré
Laia Josa Culleré
Postdoctoral Researcher, CSIC
Dirección de correo verificada de iqac.csic.es
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In the search for photocages cleavable with visible light: an overview of recent advances and chemical strategies
L Josa‐Culleré, A Llebaria
ChemPhotoChem 5 (4), 296-314, 2021
572021
Diazo group as a new chemical reporter for bioorthogonal labelling of biomolecules
L Josa-Culleré, YA Wainman, KM Brindle, FJ Leeper
RSC Advances 4 (94), 52241-52244, 2014
352014
Asymmetric Total Synthesis of (−)-(3R)-Inthomycin C
S Balcells, MB Haughey, JCL Walker, L Josa-Culleré, C Towers, ...
Organic Letters, 2018
242018
Synthetic Biomimetic Coenzymes and Alcohol Dehydrogenases for Asymmetric Catalysis
L Josa-Culleré, ASK Lahdenperä, A Ribaucourt, GT Höfler, S Gargiulo, ...
Catalysts 9 (3), 207, 2019
162019
Synthesis and bioactivity of fused-and spiro-β-lactone-lactam systems
L Josa-Culleré, C Towers, F Willenbrock, VM Macaulay, KE Christensen, ...
Organic & biomolecular chemistry 15 (25), 5373-5379, 2017
142017
Stereoselectivity in the reduction of bicyclic tetramates
L Josa-Culleré, MG Moloney, AL Thompson
Synlett 27 (11), 1677-1681, 2016
142016
Chemoselective Formation and Reaction of Densely Functionalised Bicyclic Tetramic Acids and Their Biological Activity
L Josa‐Culleré, C Towers, AL Thompson, MG Moloney
European Journal of Organic Chemistry 2017 (47), 7055-7059, 2017
122017
Antibacterial mimics of natural products by side-chain functionalization of bicyclic tetramic acids
L Josa-Culleré, A Pretsch, D Pretsch, MG Moloney
The Journal of organic chemistry 83 (17), 10303-10317, 2018
112018
Spirocyclic tetramates by sequential knoevenagel and [1, 5]-prototropic shift
L Josa-Culleré, MG Hirst, JP Lockett, AL Thompson, MG Moloney
The Journal of Organic Chemistry 84 (15), 9671-9683, 2019
92019
A Phenotypic Screen Identifies a Compound Series That Induces Differentiation of Acute Myeloid Leukemia Cells In Vitro and Shows Antitumor Effects In Vivo
L Josa-Culleré, KS Madden, TJ Cogswell, TR Jackson, TS Carter, ...
Journal of Medicinal Chemistry 64 (21), 15608-15628, 2021
62021
Aruncin B: Synthetic Studies, Structural Reassignment and Biological Evaluation
A Ribaucourt, C Towers, L Josa‐Culleré, F Willenbrock, AL Thompson, ...
Chemistry-A European Journal 23 (65), 16525-16534, 2017
62017
Visible-Light-Controlled Histone Deacetylase Inhibitors for Targeted Cancer Therapy
L Josa-Culleré, A Llebaria
Journal of medicinal chemistry 66 (3), 1909-1927, 2023
52023
Diastereoselective reduction of the tricarbonyl moiety in bicyclic tetramates giving pyroglutamates
L Josa-Culleré, KE Christensen, MG Moloney
Organic & biomolecular chemistry 16 (15), 2705-2710, 2018
42018
Scalar cross-relaxation detected in the NOESY spectra of oxazolidines and thiazolidines
TD Panduwawala, L Josa-Culleré, I Kuprov, B Odell, MG Moloney, ...
The Journal of organic chemistry 81 (10), 4142-4148, 2016
42016
A tubulin binding molecule drives differentiation of acute myeloid leukemia cells
TR Jackson, A Vuorinen, L Josa-Culleré, KS Madden, D Conole, ...
iScience 25 (8), 104787, 2022
22022
A novel tubulin binding molecule drives differentiation of acute myeloid leukaemia cells
TR Jackson, A Vuorinen, L Josa-Culleré, KS Madden, D Conole, ...
bioRxiv, 2021.06. 03.446952, 2021
22021
Phenotypic screening identifies a trisubstituted imidazo [1, 2-a] pyridine series that induces differentiation in multiple AML cell lines
L Josa-Culleré, SRG Galan, TJ Cogswell, TR Jackson, M Jay-Smith, ...
European Journal of Medicinal Chemistry, 115509, 2023
12023
Identification and Preliminary Structure-Activity Relationship Studies of 1, 5-Dihydrobenzo [e][1, 4] oxazepin-2 (3H)-ones That Induce Differentiation of Acute Myeloid Leukemia …
L Josa-Culleré, TJ Cogswell, I Georgiou, M Jay-Smith, TR Jackson, ...
Molecules 26 (21), 6648, 2021
12021
Hemithioindigo-based histone deacetylase inhibitors induce a light-dependent anticancer effect
L Josa-Culleré, CA Rodríguez, A Llebaria
2024
HDAC inhibitor derivatives induce differentiation of leukemic cells through two distinct and separable mechanisms
P Kumar, L Josa-Cullere, TR Jackson, CJR Bataille, P Vyas, TA Milne, ...
bioRxiv, 2024.01. 06.572546, 2024
2024
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