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Kevin Legge
Kevin Legge
Verified email at uiowa.edu
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Year
Accelerated migration of respiratory dendritic cells to the regional lymph nodes is limited to the early phase of pulmonary infection
KL Legge, TJ Braciale
Immunity 18 (2), 265-277, 2003
4502003
High Frequency of Autoreactive Myelin Proteolipid Protein–specific T Cells in the Periphery of Naive Mice: Mechanisms of Selection of the Self-reactive Repertoire
AC Anderson, LB Nicholson, KL Legge, V Turchin, H Zaghouani, ...
The Journal of experimental medicine 191 (5), 761-770, 2000
3342000
Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs
J McGill, N Van Rooijen, KL Legge
The Journal of experimental medicine 205 (7), 1635-1646, 2008
3052008
Age-related increases in PGD2 expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice
J Zhao, J Zhao, K Legge, S Perlman
The Journal of clinical investigation 121 (12), 4921-4930, 2011
2812011
CD8 T cells utilize TRAIL to control influenza virus infection
EL Brincks, A Katewa, TA Kucaba, TS Griffith, KL Legge
The Journal of Immunology 181 (7), 4918-4925, 2008
2782008
Innate immune control and regulation of influenza virus infections
J McGill, JW Heusel, KL Legge
Journal of leukocyte biology 86 (4), 803-812, 2009
2352009
On the role of dendritic cells in peripheral T cell tolerance and modulation of autoimmunity
KL Legge, RK Gregg, R Maldonado-Lopez, L Li, JC Caprio, M Moser, ...
The Journal of experimental medicine 196 (2), 217-227, 2002
1952002
Influenza A viral replication is blocked by inhibition of the inositol-requiring enzyme 1 (IRE1) stress pathway
IH Hassan, MS Zhang, LS Powers, JQ Shao, J Baltrusaitis, DT Rutkowski, ...
Journal of Biological Chemistry 287 (7), 4679-4689, 2012
1732012
Lymph node dendritic cells control CD8+ T cell responses through regulated FasL expression
KL Legge, TJ Braciale
Immunity 23 (6), 649-659, 2005
1652005
IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection
J McGill, N Van Rooijen, KL Legge
Journal of Experimental Medicine 207 (3), 521-534, 2010
1632010
Neurohormonal modulation of the innate immune system is proinflammatory in the prehypertensive spontaneously hypertensive rat, a genetic model of essential hypertension
SC Harwani, MW Chapleau, KL Legge, ZK Ballas, FM Abboud
Circulation research 111 (9), 1190-1197, 2012
1252012
Chronic alcohol consumption increases the severity of murine influenza virus infections
DK Meyerholz, M Edsen-Moore, J McGill, RA Coleman, RT Cook, ...
The Journal of Immunology 181 (1), 641-648, 2008
1152008
Elevated mitochondrial superoxide disrupts normal T cell development, impairing adaptive immune responses to an influenza challenge
AJ Case, JL McGill, LT Tygrett, T Shirasawa, DR Spitz, TJ Waldschmidt, ...
Free Radical Biology and Medicine 50 (3), 448-458, 2011
1122011
Cutting edge: contribution of lung-resident T cell proliferation to the overall magnitude of the antigen-specific CD8 T cell response in the lungs following murine influenza …
J McGill, KL Legge
The Journal of Immunology 183 (7), 4177-4181, 2009
1112009
Coupling of peripheral tolerance to endogenous interleukin 10 promotes effective modulation of myelin-activated T cells and ameliorates experimental allergic encephalomyelitis
KL Legge, B Min, JJ Bell, JC Caprio, L Li, RK Gregg, H Zaghouani
The Journal of experimental medicine 191 (12), 2039-2052, 2000
1022000
Pulmonary infection with influenza A virus induces site-specific germinal center and T follicular helper cell responses
AW Boyden, KL Legge, TJ Waldschmidt
PloS one 7 (7), e40733, 2012
982012
Natural killer cell recruitment to the lung during influenza A virus infection is dependent on CXCR3, CCR5, and virus exposure dose
LE Carlin, EA Hemann, ZR Zacharias, JW Heusel, KL Legge
Frontiers in immunology 9, 781, 2018
932018
T regulatory cells participate in the control of germinal centre reactions
CM Alexander, LT Tygrett, AW Boyden, KL Wolniak, KL Legge, ...
Immunology 133 (4), 452-468, 2011
852011
Protective CD8 T cell–mediated immunity against influenza a virus infection following influenza virus–like particle vaccination
EA Hemann, SM Kang, KL Legge
The Journal of Immunology 191 (5), 2486-2494, 2013
832013
Exploiting cross-priming to generate protective CD8 T-cell immunity rapidly
NLL Pham, LL Pewe, CJ Fleenor, RA Langlois, KL Legge, VP Badovinac, ...
Proceedings of the National Academy of Sciences 107 (27), 12198-12203, 2010
772010
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