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Kevin Legge
Kevin Legge
Verified email at uiowa.edu
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Year
Accelerated migration of respiratory dendritic cells to the regional lymph nodes is limited to the early phase of pulmonary infection
KL Legge, TJ Braciale
Immunity 18 (2), 265-277, 2003
4512003
High Frequency of Autoreactive Myelin Proteolipid Protein–specific T Cells in the Periphery of Naive Mice: Mechanisms of Selection of the Self-reactive Repertoire
AC Anderson, LB Nicholson, KL Legge, V Turchin, H Zaghouani, ...
The Journal of experimental medicine 191 (5), 761-770, 2000
3362000
Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs
J McGill, N Van Rooijen, KL Legge
The Journal of experimental medicine 205 (7), 1635-1646, 2008
3012008
Age-related increases in PGD2 expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice
J Zhao, J Zhao, K Legge, S Perlman
The Journal of clinical investigation 121 (12), 4921-4930, 2011
2762011
CD8 T cells utilize TRAIL to control influenza virus infection
EL Brincks, A Katewa, TA Kucaba, TS Griffith, KL Legge
The Journal of Immunology 181 (7), 4918-4925, 2008
2722008
Innate immune control and regulation of influenza virus infections
J McGill, JW Heusel, KL Legge
Journal of leukocyte biology 86 (4), 803-812, 2009
2362009
On the role of dendritic cells in peripheral T cell tolerance and modulation of autoimmunity
KL Legge, RK Gregg, R Maldonado-Lopez, L Li, JC Caprio, M Moser, ...
The Journal of experimental medicine 196 (2), 217-227, 2002
1952002
Influenza A viral replication is blocked by inhibition of the inositol-requiring enzyme 1 (IRE1) stress pathway
IH Hassan, MS Zhang, LS Powers, JQ Shao, J Baltrusaitis, DT Rutkowski, ...
Journal of Biological Chemistry 287 (7), 4679-4689, 2012
1722012
Lymph node dendritic cells control CD8+ T cell responses through regulated FasL expression
KL Legge, TJ Braciale
Immunity 23 (6), 649-659, 2005
1632005
IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection
J McGill, N Van Rooijen, KL Legge
Journal of Experimental Medicine 207 (3), 521-534, 2010
1602010
Neurohormonal modulation of the innate immune system is proinflammatory in the prehypertensive spontaneously hypertensive rat, a genetic model of essential hypertension
SC Harwani, MW Chapleau, KL Legge, ZK Ballas, FM Abboud
Circulation research 111 (9), 1190-1197, 2012
1262012
Chronic alcohol consumption increases the severity of murine influenza virus infections
DK Meyerholz, M Edsen-Moore, J McGill, RA Coleman, RT Cook, ...
The Journal of Immunology 181 (1), 641-648, 2008
1162008
Cutting edge: contribution of lung-resident T cell proliferation to the overall magnitude of the antigen-specific CD8 T cell response in the lungs following murine influenza …
J McGill, KL Legge
The Journal of Immunology 183 (7), 4177-4181, 2009
1112009
Elevated mitochondrial superoxide disrupts normal T cell development, impairing adaptive immune responses to an influenza challenge
AJ Case, JL McGill, LT Tygrett, T Shirasawa, DR Spitz, TJ Waldschmidt, ...
Free Radical Biology and Medicine 50 (3), 448-458, 2011
1102011
Coupling of peripheral tolerance to endogenous interleukin 10 promotes effective modulation of myelin-activated T cells and ameliorates experimental allergic encephalomyelitis
KL Legge, B Min, JJ Bell, JC Caprio, L Li, RK Gregg, H Zaghouani
The Journal of experimental medicine 191 (12), 2039-2052, 2000
1012000
Natural killer cell recruitment to the lung during influenza A virus infection is dependent on CXCR3, CCR5, and virus exposure dose
LE Carlin, EA Hemann, ZR Zacharias, JW Heusel, KL Legge
Frontiers in immunology 9, 343429, 2018
922018
Pulmonary infection with influenza A virus induces site-specific germinal center and T follicular helper cell responses
AW Boyden, KL Legge, TJ Waldschmidt
PloS one 7 (7), e40733, 2012
922012
T regulatory cells participate in the control of germinal centre reactions
CM Alexander, LT Tygrett, AW Boyden, KL Wolniak, KL Legge, ...
Immunology 133 (4), 452-468, 2011
852011
Protective CD8 T cell–mediated immunity against influenza a virus infection following influenza virus–like particle vaccination
EA Hemann, SM Kang, KL Legge
The Journal of Immunology 191 (5), 2486-2494, 2013
832013
Exploiting cross-priming to generate protective CD8 T-cell immunity rapidly
NLL Pham, LL Pewe, CJ Fleenor, RA Langlois, KL Legge, VP Badovinac, ...
Proceedings of the National Academy of Sciences 107 (27), 12198-12203, 2010
782010
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