Accelerated migration of respiratory dendritic cells to the regional lymph nodes is limited to the early phase of pulmonary infection KL Legge, TJ Braciale Immunity 18 (2), 265-277, 2003 | 451 | 2003 |
High Frequency of Autoreactive Myelin Proteolipid Protein–specific T Cells in the Periphery of Naive Mice: Mechanisms of Selection of the Self-reactive Repertoire AC Anderson, LB Nicholson, KL Legge, V Turchin, H Zaghouani, ... The Journal of experimental medicine 191 (5), 761-770, 2000 | 336 | 2000 |
Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs J McGill, N Van Rooijen, KL Legge The Journal of experimental medicine 205 (7), 1635-1646, 2008 | 301 | 2008 |
Age-related increases in PGD2 expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice J Zhao, J Zhao, K Legge, S Perlman The Journal of clinical investigation 121 (12), 4921-4930, 2011 | 276 | 2011 |
CD8 T cells utilize TRAIL to control influenza virus infection EL Brincks, A Katewa, TA Kucaba, TS Griffith, KL Legge The Journal of Immunology 181 (7), 4918-4925, 2008 | 272 | 2008 |
Innate immune control and regulation of influenza virus infections J McGill, JW Heusel, KL Legge Journal of leukocyte biology 86 (4), 803-812, 2009 | 236 | 2009 |
On the role of dendritic cells in peripheral T cell tolerance and modulation of autoimmunity KL Legge, RK Gregg, R Maldonado-Lopez, L Li, JC Caprio, M Moser, ... The Journal of experimental medicine 196 (2), 217-227, 2002 | 195 | 2002 |
Influenza A viral replication is blocked by inhibition of the inositol-requiring enzyme 1 (IRE1) stress pathway IH Hassan, MS Zhang, LS Powers, JQ Shao, J Baltrusaitis, DT Rutkowski, ... Journal of Biological Chemistry 287 (7), 4679-4689, 2012 | 172 | 2012 |
Lymph node dendritic cells control CD8+ T cell responses through regulated FasL expression KL Legge, TJ Braciale Immunity 23 (6), 649-659, 2005 | 163 | 2005 |
IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection J McGill, N Van Rooijen, KL Legge Journal of Experimental Medicine 207 (3), 521-534, 2010 | 160 | 2010 |
Neurohormonal modulation of the innate immune system is proinflammatory in the prehypertensive spontaneously hypertensive rat, a genetic model of essential hypertension SC Harwani, MW Chapleau, KL Legge, ZK Ballas, FM Abboud Circulation research 111 (9), 1190-1197, 2012 | 126 | 2012 |
Chronic alcohol consumption increases the severity of murine influenza virus infections DK Meyerholz, M Edsen-Moore, J McGill, RA Coleman, RT Cook, ... The Journal of Immunology 181 (1), 641-648, 2008 | 116 | 2008 |
Cutting edge: contribution of lung-resident T cell proliferation to the overall magnitude of the antigen-specific CD8 T cell response in the lungs following murine influenza … J McGill, KL Legge The Journal of Immunology 183 (7), 4177-4181, 2009 | 111 | 2009 |
Elevated mitochondrial superoxide disrupts normal T cell development, impairing adaptive immune responses to an influenza challenge AJ Case, JL McGill, LT Tygrett, T Shirasawa, DR Spitz, TJ Waldschmidt, ... Free Radical Biology and Medicine 50 (3), 448-458, 2011 | 110 | 2011 |
Coupling of peripheral tolerance to endogenous interleukin 10 promotes effective modulation of myelin-activated T cells and ameliorates experimental allergic encephalomyelitis KL Legge, B Min, JJ Bell, JC Caprio, L Li, RK Gregg, H Zaghouani The Journal of experimental medicine 191 (12), 2039-2052, 2000 | 101 | 2000 |
Natural killer cell recruitment to the lung during influenza A virus infection is dependent on CXCR3, CCR5, and virus exposure dose LE Carlin, EA Hemann, ZR Zacharias, JW Heusel, KL Legge Frontiers in immunology 9, 343429, 2018 | 92 | 2018 |
Pulmonary infection with influenza A virus induces site-specific germinal center and T follicular helper cell responses AW Boyden, KL Legge, TJ Waldschmidt PloS one 7 (7), e40733, 2012 | 92 | 2012 |
T regulatory cells participate in the control of germinal centre reactions CM Alexander, LT Tygrett, AW Boyden, KL Wolniak, KL Legge, ... Immunology 133 (4), 452-468, 2011 | 85 | 2011 |
Protective CD8 T cell–mediated immunity against influenza a virus infection following influenza virus–like particle vaccination EA Hemann, SM Kang, KL Legge The Journal of Immunology 191 (5), 2486-2494, 2013 | 83 | 2013 |
Exploiting cross-priming to generate protective CD8 T-cell immunity rapidly NLL Pham, LL Pewe, CJ Fleenor, RA Langlois, KL Legge, VP Badovinac, ... Proceedings of the National Academy of Sciences 107 (27), 12198-12203, 2010 | 78 | 2010 |