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John W. Bullen, Ph.D.
John W. Bullen, Ph.D.
Associate Director, AstraZeneca
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
Recombinant human leptin in women with hypothalamic amenorrhea
CK Welt, JL Chan, J Bullen, R Murphy, P Smith, AM DePaoli, A Karalis, ...
New England Journal of Medicine 351 (10), 987-997, 2004
10472004
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA
C Zhang, D Samanta, H Lu, JW Bullen, H Zhang, I Chen, X He, ...
Proceedings of the National Academy of Sciences 113 (14), E2047-E2056, 2016
9672016
Circulating adiponectin and expression of adiponectin receptors in human skeletal muscle: associations with metabolic parameters and insulin resistance and regulation by …
M Blüher, JW Bullen Jr, JH Lee, S Kralisch, M Fasshauer, N Klöting, ...
The Journal of Clinical Endocrinology & Metabolism 91 (6), 2310-2316, 2006
3932006
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
H Zhang, H Lu, L Xiang, JW Bullen, C Zhang, D Samanta, DM Gilkes, ...
Proceedings of the National Academy of Sciences 112 (45), E6215-E6223, 2015
3632015
Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity
RJ Copeland, JW Bullen, GW Hart
American Journal of Physiology-Endocrinology and Metabolism 295 (1), E17-E28, 2008
3102008
Total and High-Molecular-Weight Adiponectin in Breast Cancer: In Vitro and in Vivo Studies
A Körner, K Pazaitou-Panayiotou, T Kelesidis, I Kelesidis, CJ Williams, ...
The Journal of Clinical Endocrinology & Metabolism 92 (3), 1041-1048, 2007
2942007
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
H Lu, D Samanta, L Xiang, H Zhang, H Hu, I Chen, JW Bullen, ...
Proceedings of the National Academy of Sciences 112 (33), E4600-E4609, 2015
2462015
Ghrelin levels are not regulated by recombinant leptin administration and/or three days of fasting in healthy subjects
JL Chan, J Bullen, JH Lee, N Yiannakouris, CS Mantzoros
The Journal of Clinical Endocrinology & Metabolism 89 (1), 335-343, 2004
2132004
Cross-talk between two essential nutrient-sensitive enzymes: O-GlcNAc transferase (OGT) and AMP-activated protein kinase (AMPK)
JW Bullen, JL Balsbaugh, D Chanda, J Shabanowitz, DF Hunt, ...
Journal of Biological Chemistry 289 (15), 10592-10606, 2014
2112014
Regulation of adiponectin and its receptors in response to development of diet-induced obesity in mice
JW Bullen Jr, S Bluher, T Kelesidis, CS Mantzoros
American Journal of Physiology-Endocrinology and Metabolism 292 (4), E1079-E1086, 2007
1982007
Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype
L Xiang, DM Gilkes, H Hu, N Takano, W Luo, H Lu, JW Bullen, D Samanta, ...
Oncotarget 5 (24), 12509, 2014
1302014
Circulating resistin in lean, obese, and insulin-resistant mouse models: lack of association with insulinemia and glycemia
JH Lee, JW Bullen Jr, VL Stoyneva, CS Mantzoros
American Journal of Physiology-Endocrinology and Metabolism 288 (3), E625-E632, 2005
1282005
Protein kinase A–dependent phosphorylation stimulates the transcriptional activity of hypoxia-inducible factor 1
JW Bullen, I Tchernyshyov, RJ Holewinski, L DeVine, F Wu, ...
Science signaling 9 (430), ra56-ra56, 2016
1162016
Responsiveness to peripherally administered melanocortins in lean and obese mice
S Bluher, M Ziotopoulou, JW Bullen Jr, SJ Moschos, L Ungsunan, ...
Diabetes 53 (1), 82-90, 2004
992004
Recombinant methionyl human leptin administration to achieve high physiologic or pharmacologic leptin levels does not alter circulating inflammatory marker levels in humans …
JL Chan, J Bullen, V Stoyneva, AM DePaoli, C Addy, CS Mantzoros
The Journal of Clinical Endocrinology & Metabolism 90 (3), 1618-1624, 2005
832005
Ciliary Neurotrophic FactorAx15 Alters Energy Homeostasis, Decreases Body Weight, and Improves Metabolic Control in Diet-Induced Obese and UCP1-DTA Mice
S Bluher, S Moschos, J Bullen Jr, E Kokkotou, E Maratos-Flier, ...
Diabetes 53 (11), 2787-2796, 2004
752004
HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells
L Xiang, DM Gilkes, H Hu, W Luo, JW Bullen, H Liang, GL Semenza
Oncotarget 6 (14), 11768, 2015
742015
Recombinant methionyl human leptin administration activates signal transducer and activator of transcription 3 signaling in peripheral blood mononuclear cells in vivo and …
JL Chan, SJ Moschos, J Bullen, K Heist, X Li, YB Kim, BB Kahn, ...
The Journal of Clinical Endocrinology & Metabolism 90 (3), 1625-1631, 2005
662005
Myelin-associated glycoprotein (MAG) protects neurons from acute toxicity using a ganglioside-dependent mechanism
NR Mehta, T Nguyen, JW Bullen Jr, JW Griffin, RL Schnaar
ACS chemical neuroscience 1 (3), 215-222, 2010
402010
Elevated leptin fragments in renal failure correlate with BMI and haematopoiesis and are normalized by haemodialysis
DN Stamatiadis, JL Chan, R Cogswell, HC Stefanopoulou, J Bullen, ...
Clinical endocrinology 60 (4), 434-441, 2004
402004
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Articles 1–20