| Oncogenic K-Ras upregulates ITGA6 expression via FOSL1 to induce anoikis resistance and synergizes with αV-Class integrins to promote EMT K Zhang, SM Myllymäki, P Gao, R Devarajan, V Kytölä, M Nykter, GH Wei, ... Oncogene 36 (41), 5681-5694, 2017 | 61 | 2017 |
| Pan-Cancer analysis of the expression and regulation of matrisome genes across 32 tumor types V Izzi, J Lakkala, R Devarajan, A Kääriäinen, J Koivunen, R Heljasvaara, ... Matrix Biology Plus 1, 100004, 2019 | 41 | 2019 |
| An extracellular matrix signature in leukemia precursor cells and acute myeloid leukemia V Izzi, J Lakkala, R Devarajan, H Ruotsalainen, ER Savolainen, ... Haematologica 102 (7), e245, 2017 | 26 | 2017 |
| Lack of collagen XVIII leads to lipodystrophy and perturbs hepatic glucose and lipid homeostasis T Petäistö, D Vicente, KA Mäkelä, MA Finnilä, I Miinalainen, J Koivunen, ... The Journal of Physiology 598 (16), 3373-3393, 2020 | 17 | 2020 |
| Expression of a specific extracellular matrix signature is a favorable prognostic factor in acute myeloid leukemia V Izzi, J Lakkala, R Devarajan, ER Savolainen, P Koistinen, ... Leukemia research reports 9, 9-13, 2018 | 16 | 2018 |
| The amino-terminal oligomerization domain of Angiopoietin-2 affects vascular remodeling, mammary gland tumor growth, and lung metastasis in mice E Kapiainen, MK Kihlström, R Pietilä, M Kaakinen, VP Ronkainen, H Tu, ... Cancer Research 81 (1), 129-143, 2021 | 12 | 2021 |
| Deletion of Col15a1 Modulates the Tumour Extracellular Matrix and Leads to Increased Tumour Growth in the MMTV-PyMT Mouse Mammary Carcinoma Model G Martínez-Nieto, R Heljasvaara, A Heikkinen, HK Kaski, R Devarajan, ... International Journal of Molecular Sciences 22 (18), 9978, 2021 | 10 | 2021 |
| Tumor suppressor MCPH1 regulates gene expression profiles related to malignant conversion and chromosomal assembly A Tervasmäki, T Mantere, L Eshraghi, N Laurila, H Tuppurainen, ... International journal of cancer 145 (8), 2070-2081, 2019 | 9 | 2019 |
| Vanin 1 (VNN1) levels predict poor outcome in acute myeloid leukemia V Izzi, J Lakkala, R Devarajan, ER Savolainen, P Koistinen, ... John Wiley & Sons, 2017 | 9 | 2017 |
| Disassembly of α6β4-mediated hemidesmosomal adhesions promotes tumorigenesis in PTEN-negative prostate cancer by targeting plectin to focal adhesions T Wenta, A Schmidt, Q Zhang, R Devarajan, P Singh, X Yang, A Ahtikoski, ... Oncogene 41 (30), 3804-3820, 2022 | 8 | 2022 |
| Upregulated integrin α11 in the stroma of cutaneous squamous cell carcinoma promotes skin carcinogenesis GA Martínez-Nieto, HR Teppo, N Petrelius, V Izzi, R Devarajan, T Petäistö, ... Frontiers in Oncology 12, 981009, 2022 | 5 | 2022 |
| GATA2 co-opts TGFβ1/SMAD4 oncogenic signaling and inherited variants at 6q22 to modulate prostate cancer progression X Yang, Q Zhang, S Li, R Devarajan, B Luo, Z Tan, Z Wang, N Giannareas, ... Journal of Experimental & Clinical Cancer Research 42 (1), 198, 2023 | 2 | 2023 |
| Collagen XVIII promotes breast cancer through EGFR/ErbB signaling and its ablation improves the efficacy of ErbB-targeting inhibitors R Devarajan, H Peltoketo, V Izzi, H Ruotsalainen, S Kauppila, ... bioRxiv, 2022.01. 10.474416, 2022 | 2 | 2022 |
| Targeting collagen XVIII improves the efficiency of ErbB inhibitors in breast cancer models R Devarajan, V Izzi, H Peltoketo, G Rask, S Kauppila, MR Väisänen, ... The Journal of Clinical Investigation 133 (18), 2023 | 1 | 2023 |
| The Frizzled-like domain from collagen XVIII (FZC18) controls hematopoiesis and myeloidogenesis in vivo V Izzi, DG Vicente, R Devarajan, H Ruotsalainen, R Heljasvaara, ... Immunology 137, 233-233, 2012 | 1 | 2012 |
| Dampened regulatory circuitry of TEAD1/ITGA1/ITGA2 promotes TGFβ1 signaling to orchestrate prostate cancer progression SP Cruz, Q Zhang, R Devarajan, C Paia, B Luo, K Zhang, S Koivusalo, ... Advanced Science, 2305547, 2024 | | 2024 |
| Patient-derived prostate cancer organoids require α6-integrins for self-renewal and recapitulate genetic heterogeneity and histopathology of the original tumors R Devarajan, A Hawash, S Koivusalo, A Tervasmäki, T Mattila, Q Zhang, ... | | 2023 |
| TEAD1 regulates ITGA1 and ITGA2 to control prostate cancer progression CP Sara, Z Qin, D Raman, C Paia, L Binjie, Z Kai, X Jihan, A Anne, ... bioRxiv, 2023.04. 12.536554, 2023 | | 2023 |
| Tyvikalvokollageenin toiminnan estäminen parantaa syöpälääkkeiden tehokkuutta R Devarajan, V Izzi, H Peltoketo, G Rask, S Kauppila, MR Väisänen, ... Duodecim 139 (20), 1663, 2023 | | 2023 |
| Disassembly of hemidesmosomes promotes tumorigenesis in PTEN-negative prostate cancer by targeting plectin into focal adhesions T Wenta, A Schmidt, Q Zhang, R Devarajan, P Singh, X Yang, A Ahtikoski, ... bioRxiv, 2021.11. 08.467671, 2021 | | 2021 |
