Membrane potential fluorescence: a rapid and highly sensitive assay for nicotinic receptor channel function RW Fitch, Y Xiao, KJ Kellar, JW Daly Proceedings of the National Academy of Sciences 100 (8), 4909-4914, 2003 | 119 | 2003 |
Bioassay-Guided Isolation of Epiquinamide, a Novel Quinolizidine Alkaloid and Nicotinic Agonist from an Ecuadoran Poison Frog, Epipedobates tricolor RW Fitch, HM Garraffo, TF Spande, HJC Yeh, JW Daly Journal of Natural Products 66 (10), 1345-1350, 2003 | 99 | 2003 |
A facile oxidation of alcohols using pyridinium chlorochromate/silica gel FA Luzzio, RW Fitch, WJ Moore, KJ Mudd Journal of chemical education 76 (7), 974, 1999 | 72 | 1999 |
Novel irreversible small molecule inhibitors of replication protein A display single-agent activity and synergize with cisplatin TM Neher, D Bodenmiller, RW Fitch, SI Jalal, JJ Turchi Molecular cancer therapeutics 10 (10), 1796-1806, 2011 | 64 | 2011 |
Epiquinamide: a poison that wasn’t from a frog that was RW Fitch, GD Sturgeon, SR Patel, TF Spande, HM Garraffo, JW Daly, ... Journal of natural products 72 (2), 243-247, 2009 | 61 | 2009 |
Phantasmidine: An Epibatidine Congener from the Ecuadorian Poison Frog Epipedobates anthonyi RW Fitch, TF Spande, HM Garraffo, HJC Yeh, JW Daly Journal of natural products 73 (3), 331-337, 2010 | 60 | 2010 |
Formal Synthesis of (+)- and (−)-Perhydrohistrionicotoxin: A “Double Henry”/Enzymatic Desymmetrization Route to the Kishi Lactam1 FA Luzzio, RW Fitch The Journal of Organic Chemistry 64 (15), 5485-5493, 1999 | 58 | 1999 |
N,N-Acetals as N-Acyliminium Ion Precursors: Synthesis and Absolute Stereochemistry of Epiquinamide MA Wijdeven, R Wijtmans, RJF van den Berg, W Noorduin, ... Organic Letters 10 (18), 4001-4003, 2008 | 56 | 2008 |
Thiophene-anthranilamides as highly potent and orally available factor Xa inhibitors B Ye, DO Arnaiz, YL Chou, BD Griedel, R Karanjawala, W Lee, ... Journal of medicinal chemistry 50 (13), 2967-2980, 2007 | 52 | 2007 |
Halogenated and isosteric cytisine derivatives with increased affinity and functional activity at nicotinic acetylcholine receptors RW Fitch, Y Kaneko, P Klaperski, JW Daly, G Seitz, D Gündisch Bioorganic & medicinal chemistry letters 15 (4), 1221-1224, 2005 | 45 | 2005 |
Targeting the OB-folds of replication protein A with small molecules VJ Anciano Granadillo, JN Earley, SC Shuck, MM Georgiadis, RW Fitch, ... Journal of nucleic acids 2010, 2010 | 32 | 2010 |
Phytochemical investigation and in vitro cytotoxic evaluation of alkaloids from Abuta rufescens DS Swaffar, CJ Holley, RW Fitch, KR Elkin, C Zhang, JP Sturgill, ... Planta medica 78 (03), 230-232, 2012 | 27 | 2012 |
The aluminum amalgam reduction of 2-nitroalkanols promoted by ultrasound RW Fitch, FA Luzzio Tetrahedron letters 35 (33), 6013-6016, 1994 | 26 | 1994 |
Polyethylene glycol-based homologated ligands for nicotinic acetylcholine receptors BA Scates, BL Lashbrook, BC Chastain, K Tominaga, BT Elliott, ... Bioorganic & medicinal chemistry 16 (24), 10295-10300, 2008 | 25 | 2008 |
Molecular signatures of phytol-derived immunostimulants in the context of chemokine–cytokine microenvironment and enhanced immune response Y Aachoui, RR Chowdhury, RW Fitch, SK Ghosh Cellular immunology 271 (2), 227-238, 2011 | 24 | 2011 |
Homoepiboxidines: further potent agonists for nicotinic receptors RW Fitch, XF Pei, Y Kaneko, T Gupta, D Shi, I Federova, JW Daly Bioorganic & medicinal chemistry 12 (1), 179-190, 2004 | 24 | 2004 |
Synthetic adjuvants for vaccine formulations: Evaluation of new phytol derivatives in induction and persistence of specific immune response Y Aachoui, ML Schulte, RW Fitch, SK Ghosh Cellular Immunology 271 (2), 308-318, 2011 | 23 | 2011 |
Asymmetric Synthesis of Pyrrolizidines, Indolizidines and Quinolizidines via a Double Reductive Cyclisation Protocol SG Davies, AM Fletcher, PM Roberts, JE Thomson Synlett 28 (20), 2697-2706, 2017 | 17 | 2017 |
Characterization of β-leptinotarsin-h and the effects of calcium flux antagonists on its activity RD Crosland, RW Fitch, HB Hines Toxicon 45 (7), 829-841, 2005 | 17 | 2005 |
Ultrasound in natural products synthesis: applications to the synthesis of histrionicotoxin via nitroalkanal acetals RW Fitch, FA Luzzio Ultrasonics Sonochemistry 4 (2), 99-107, 1997 | 17 | 1997 |