Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli BA Pfeifer, SJ Admiraal, H Gramajo, DE Cane, C Khosla Science 291 (5509), 1790-1792, 2001 | 947 | 2001 |
Transcriptional regulation of the redD transcriptional activator gene accounts for growth‐phase‐dependent production of the antibiotic undecylprodigiosin in Streptomyces … E Takano, HC Gramajo, E Strauch, N Andres, J White, MJ Bibb Molecular microbiology 6 (19), 2797-2804, 1992 | 273 | 1992 |
Stationary‐phase production of the antibiotic actinorhodin in Streptomyces coelicolor A3(2) is transcriptionally regulated HC Gramajo, E Takano, MJ Bibb Molecular microbiology 7 (6), 837-845, 1993 | 264 | 1993 |
Fatty acid biosynthesis in actinomycetes G Gago, L Diacovich, A Arabolaza, SC Tsai, H Gramajo FEMS microbiology reviews 35 (3), 475-497, 2011 | 184 | 2011 |
Production of the Potent Antibacterial Polyketide Erythromycin C in Escherichia coli S Peirú, HG Menzella, E Rodriguez, J Carney, H Gramajo Applied and environmental microbiology 71 (5), 2539-2547, 2005 | 148 | 2005 |
Multiple Pathways for Triacylglycerol Biosynthesis in Streptomyces coelicolor A Arabolaza, E Rodriguez, S Altabe, H Alvarez, H Gramajo Applied and environmental microbiology 74 (9), 2573-2582, 2008 | 145 | 2008 |
Structure-based inhibitor design of AccD5, an essential acyl-CoA carboxylase carboxyltransferase domain of Mycobacterium tuberculosis TW Lin, MM Melgar, D Kurth, SJ Swamidass, J Purdon, T Tseng, G Gago, ... Proceedings of the National Academy of Sciences 103 (9), 3072-3077, 2006 | 132 | 2006 |
The Surfactin-Like Lipopeptides From Bacillus spp.: Natural Biodiversity and Synthetic Biology for a Broader Application Range A Théatre, C Cano-Prieto, M Bartolini, Y Laurin, M Deleu, J Niehren, ... Frontiers in Bioengineering and Biotechnology 9, 623701, 2021 | 124 | 2021 |
Proteomic studies of diauxic lag in the differentiating prokaryote Streptomyces coelicolor reveal a regulatory network of stress‐induced proteins and central … J Novotna, J Vohradsky, P Berndt, H Gramajo, H Langen, XM Li, W Minas, ... Molecular Microbiology 48 (5), 1289-1303, 2003 | 117 | 2003 |
Purification and characterization of the acyl carrier protein of the Streptomyces glaucescens tetracenomycin C polyketide synthase B Shen, RG Summers, H Gramajo, MJ Bibb, CR Hutchinson Journal of bacteriology 174 (11), 3818-3821, 1992 | 116 | 1992 |
Genetic and biochemical characterization of the α and β components of a propionyl-CoA carboxylase complex of Streptomyces coelicolor A3(2) E Rodrıguez, H Gramajo Microbiology 145 (11), 3109-3119, 1999 | 114 | 1999 |
Kinetic and structural analysis of a new group of acyl-CoA carboxylases found in Streptomyces coelicolor A3 (2) L Diacovich, S Peiru, D Kurth, E Rodrıguez, F Podestá, C Khosla, ... Journal of Biological Chemistry 277 (34), 31228-31236, 2002 | 104 | 2002 |
Biochemical and Structural Characterization of an Essential Acyl Coenzyme A Carboxylase from Mycobacterium tuberculosis G Gago, D Kurth, L Diacovich, SC Tsai, H Gramajo Journal of bacteriology 188 (2), 477-486, 2006 | 100 | 2006 |
Role of an Essential Acyl Coenzyme A Carboxylase in the Primary and Secondary Metabolism of Streptomyces coelicolor A3(2) E Rodrıguez, C Banchio, L Diacovich, MJ Bibb, H Gramajo Applied and environmental microbiology 67 (9), 4166-4176, 2001 | 92 | 2001 |
Crystal Structure of the β-Subunit of Acyl-CoA Carboxylase: Structure-Based Engineering of Substrate Specificity, L Diacovich, DL Mitchell, H Pham, G Gago, MM Melgar, C Khosla, ... Biochemistry 43 (44), 14027-14036, 2004 | 91 | 2004 |
The biosynthetic genes for disorazoles, potent cytotoxic compounds that disrupt microtubule formation R Carvalho, R Reid, N Viswanathan, H Gramajo, B Julien Gene 359, 91-98, 2005 | 90 | 2005 |
Overproduction and localization of components of the polyketide synthase of Streptomyces glaucescens involved in the production of the antibiotic tetracenomycin C HC Gramajo, J White, CR Hutchinson, MJ Bibb Journal of bacteriology 173 (20), 6475-6483, 1991 | 71 | 1991 |
Lipid metabolism and its implication in mycobacteria–host interaction G Gago, L Diacovich, H Gramajo Current opinion in microbiology 41, 36-42, 2018 | 68 | 2018 |
Influence relevance voting: an accurate and interpretable virtual high throughput screening method SJ Swamidass, CA Azencott, TW Lin, H Gramajo, SC Tsai, P Baldi Journal of chemical information and modeling 49 (4), 756-766, 2009 | 67 | 2009 |
Novel Escherichia coli strain allows efficient recombinant protein production using lactose as inducer HG Menzella, EA Ceccarelli, HC Gramajo Biotechnology and bioengineering 82 (7), 809-817, 2003 | 64 | 2003 |