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Günter Niegisch
Günter Niegisch
Heinrich-Heine-University, Medical Faculty, Department of Urology, GU oncology
Verified email at hhu.de - Homepage
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Year
Pembrolizumab alone or combined with chemotherapy versus chemotherapy as first-line therapy for advanced urothelial carcinoma (KEYNOTE-361): a randomised, open-label, phase 3 trial
T Powles, T Csőszi, M Özgüroğlu, N Matsubara, L Géczi, SYS Cheng, ...
The Lancet Oncology 22 (7), 931-945, 2021
4102021
Durvalumab alone and durvalumab plus tremelimumab versus chemotherapy in previously untreated patients with unresectable, locally advanced or metastatic urothelial carcinoma …
T Powles, MS van der Heijden, D Castellano, MD Galsky, Y Loriot, ...
The Lancet Oncology 21 (12), 1574-1588, 2020
3862020
Ramucirumab plus docetaxel versus placebo plus docetaxel in patients with locally advanced or metastatic urothelial carcinoma after platinum-based therapy (RANGE): a randomised …
DP Petrylak, R De Wit, KN Chi, A Drakaki, CN Sternberg, H Nishiyama, ...
The Lancet 390 (10109), 2266-2277, 2017
2412017
Randomized phase III trial of 2nd line gemcitabine and paclitaxel chemotherapy in patients with advanced bladder cancer: short-term versus prolonged treatment [German …
P Albers, SI Park, G Niegisch, G Fechner, U Steiner, J Lehmann, ...
Annals of Oncology 22 (2), 288-294, 2011
1442011
Time from prior chemotherapy enhances prognostic risk grouping in the second-line setting of advanced urothelial carcinoma: a retrospective analysis of pooled, prospective …
G Sonpavde, GR Pond, R Fougeray, TK Choueiri, AQ Qu, DJ Vaughn, ...
European urology 63 (4), 717-723, 2013
1242013
The long noncoding RNA HOTAIR has tissue and cell type-dependent effects on HOX gene expression and phenotype of urothelial cancer cells
J Heubach, J Monsior, R Deenen, G Niegisch, T Szarvas, C Niedworok, ...
Molecular cancer 14, 1-17, 2015
1182015
Changes in histone deacetylase (HDAC) expression patterns and activity of HDAC inhibitors in urothelial cancers
G Niegisch, J Knievel, A Koch, C Hader, U Fischer, P Albers, WA Schulz
Urologic Oncology: Seminars and Original Investigations 31 (8), 1770-1779, 2013
972013
Impact of contemporary patterns of chemotherapy utilization on survival in patients with advanced cancer of the urinary tract: a Retrospective International Study of Invasive …
A Bamias, K Tzannis, LC Harshman, SJ Crabb, YN Wong, SK Pal, ...
Annals of Oncology 29 (2), 361-369, 2018
752018
Five-factor prognostic model for survival of post-platinum patients with metastatic urothelial carcinoma receiving PD-L1 inhibitors
G Sonpavde, J Manitz, C Gao, D Tayama, C Kaiser, D Hennessy, ...
The Journal of urology 204 (6), 1173-1179, 2020
662020
Effects of novel HDAC inhibitors on urothelial carcinoma cells
A Kaletsch, M Pinkerneil, MJ Hoffmann, AA Jaguva Vasudevan, C Wang, ...
Clinical epigenetics 10, 1-18, 2018
662018
Single-agent taxane versus taxane-containing combination chemotherapy as salvage therapy for advanced urothelial carcinoma
G Sonpavde, GR Pond, TK Choueiri, S Mullane, G Niegisch, P Albers, ...
European Urology 69 (4), 634-641, 2016
662016
Pathological T0 following radical cystectomy with or without neoadjuvant chemotherapy: a useful surrogate
HJ Lavery, KD Stensland, G Niegisch, P Albers, MJ Droller
The Journal of urology 191 (4), 898-906, 2014
652014
A real-world data study to evaluate treatment patterns, clinical characteristics and survival outcomes for first-and second-line treatment in locally advanced and metastatic …
G Niegisch, H Gerullis, SW Lin, J Pavlova, A Gondos, A Rudolph, G Haas, ...
Journal of Cancer 9 (8), 1337, 2018
622018
Genotyping NAT2 with only two SNPs (rs1041983 and rs1801280) outperforms the tagging SNP rs1495741 and is equivalent to the conventional 7-SNP NAT2 genotype
S Selinski, M Blaszkewicz, ML Lehmann, D Ovsiannikov, O Moormann, ...
Pharmacogenetics and genomics 21 (10), 673-678, 2011
612011
Evaluation of the therapeutic potential of the novel isotype specific HDAC inhibitor 4SC-202 in urothelial carcinoma cell lines
M Pinkerneil, MJ Hoffmann, H Kohlhof, WA Schulz, G Niegisch
Targeted oncology 11, 783-798, 2016
602016
Nomogram-based prediction of overall survival in patients with metastatic urothelial carcinoma receiving first-line platinum-based chemotherapy: retrospective international …
A Necchi, G Sonpavde, SL Vullo, D Giardiello, A Bamias, SJ Crabb, ...
European urology 71 (2), 281-289, 2017
592017
Inhibition of class I histone deacetylases 1 and 2 promotes urothelial carcinoma cell death by various mechanisms
M Pinkerneil, MJ Hoffmann, R Deenen, K Koehrer, T Arent, WA Schulz, ...
Molecular cancer therapeutics 15 (2), 299-312, 2016
572016
HERV-K and LINE-1 DNA Methylation and Reexpression in Urothelial Carcinoma
U Kreimer, WA Schulz, A Koch, G Niegisch, W Goering
Frontiers in Oncology 3, 255, 2013
572013
Concomitant downregulation of the imprinted genes DLK1 and MEG3 at 14q32.2 by epigenetic mechanisms in urothelial carcinoma
A Greife, J Knievel, T Ribarska, G Niegisch, WA Schulz
Clinical epigenetics 6, 1-13, 2014
512014
Limited efficacy of specific HDAC6 inhibition in urothelial cancer cells
L Rosik, G Niegisch, U Fischer, M Jung, WA Schulz, MJ Hoffmann
Cancer biology & therapy 15 (6), 742-757, 2014
512014
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