Alkylphospholipids: An update on molecular mechanisms and clinical relevance P Rios-Marco, C Marco, X Gálvez, JM Jiménez-López, MP Carrasco Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (9), 1657-1667, 2017 | 74 | 2017 |
Alterations in the homeostasis of phospholipids and cholesterol by antitumor alkylphospholipids JM Jiménez-López, P Ríos-Marco, C Marco, JL Segovia, MP Carrasco Lipids in health and disease 9, 1-10, 2010 | 72 | 2010 |
Dynamic micellar oligomers of amyloid beta peptides play a crucial role in their aggregation mechanisms B Morel, MP Carrasco, S Jurado, C Marco, F Conejero-Lara Physical Chemistry Chemical Physics 20 (31), 20597-20614, 2018 | 46 | 2018 |
Disruption of cellular cholesterol transport and homeostasis as a novel mechanism of action of membrane‐targeted alkylphospholipid analogues MP Carrasco, JM Jiménez‐López, P Ríos‐Marco, JL Segovia, C Marco British journal of pharmacology 160 (2), 355-366, 2010 | 40 | 2010 |
Hexadecylphosphocholine inhibits phosphatidylcholine biosynthesis and the proliferation of HepG2 cells JM Jiménez‐López, MP Carrasco, JL Segovia, C Marco European journal of biochemistry 269 (18), 4649-4655, 2002 | 39 | 2002 |
Chronic ingestion of ethanol stimulates lipogenic response in rat hepatocytes MP Carrasco, C Marco, JL Segovia Life Sciences 68 (11), 1295-1304, 2001 | 36 | 2001 |
Design, synthesis, theoretical calculations and biological evaluation of new non-symmetrical choline kinase inhibitors B Rubio-Ruíz, A Conejo-García, P Ríos-Marco, MP Carrasco-Jiménez, ... European journal of medicinal chemistry 50, 154-162, 2012 | 33 | 2012 |
Comparative study of the effects of short-and long-term ethanol treatment and alcohol withdrawal on phospholipid biosynthesis in rat hepatocytes MP Carrasco, JM Jimenez-Lopez, JL Segovia, C Marco Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular …, 2002 | 33 | 2002 |
Effects of different nutritional conditions on chick liver mevalonate-activating enzymes D González-Pacanowska, C Marco, J Garcia-Martinez, E Garcia-Peregrin Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism 875 (3), 605-609, 1986 | 31 | 1986 |
Relationship between changes in free cholesterol and pyrophosphomevalonate decarboxylase activity during myelination C Marco, D Gonzalez-Pacanowska, A Linares, E Garcia-Peregrin Neurochemical Research 8, 711-721, 1983 | 30 | 1983 |
Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1) S Schiaffino-Ortega, E Baglioni, E Mariotto, R Bortolozzi, ... Scientific reports 6 (1), 23793, 2016 | 29 | 2016 |
Discovery of a new binding site on human choline kinase α1: design, synthesis, crystallographic studies, and biological evaluation of asymmetrical bispyridinium derivatives B Rubio-Ruiz, A Figuerola-Conchas, J Ramos-Torrecillas, ... Journal of medicinal chemistry 57 (2), 507-515, 2014 | 29 | 2014 |
Hexadecylphosphocholine alters nonvesicular cholesterol traffic from the plasma membrane to the endoplasmic reticulum and inhibits the synthesis of sphingomyelin in HepG2 cells C Marco, JM Jiménez-López, P Ríos-Marco, JL Segovia, MP Carrasco The international journal of biochemistry & cell biology 41 (6), 1296-1303, 2009 | 29 | 2009 |
Role of mevalonate-5-pyrophosphate decarboxylase in the regulation of chick intestinal cholesterogenesis D Gonzalez-Pacanowska, C Marco, J Garcia-Martinez, E Garcia-Peregrin Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism 833 (3), 449-455, 1985 | 26 | 1985 |
Choline kinase inhibitors EB-3D and EB-3P interferes with lipid homeostasis in HepG2 cells A Sola-Leyva, LC López-Cara, P Ríos-Marco, A Ríos, C Marco, ... Scientific Reports 9 (1), 5109, 2019 | 24 | 2019 |
New non-symmetrical choline kinase inhibitors S Schiaffino-Ortega, LC López-Cara, P Rios-Marco, ... Bioorganic & medicinal chemistry 21 (22), 7146-7154, 2013 | 24 | 2013 |
Hexadecylphosphocholine inhibits phosphatidylcholine synthesis via both the methylation of phosphatidylethanolamine and CDP-choline pathways in HepG2 cells JM Jiménez-López, MP Carrasco, JL Segovia, C Marco The international journal of biochemistry & cell biology 36 (1), 153-161, 2004 | 24 | 2004 |
Ethanol and lipid metabolism Differential effects on liver and brain microsomes MC Sanchez-Amate, JM Zurera, MP Carrasco, JL Segovia, C Marco FEBS letters 293 (1-2), 215-218, 1991 | 23 | 1991 |
Resistance of HepG2 cells against the adverse effects of ethanol related to neutral lipid and phospholipid metabolism JM Jiménez-López, MP Carrasco, JL Segovia, C Marco Biochemical pharmacology 63 (8), 1485-1490, 2002 | 22 | 2002 |
Postnatal Development of the Sterol and Nonsterol Mevalonate Metabolism in Chick Liver and Kidneys: Effect of Cholesterol Feeding JA Aguilera, A Linares, C Marco, V Arce, E Garcia-Peregrin Annals of nutrition and metabolism 28 (6), 342-349, 1984 | 22 | 1984 |