Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans PS Arunachalam, F Wimmers, CKP Mok, RAPM Perera, M Scott, T Hagan, ... Science 369 (6508), 1210-1220, 2020 | 1061 | 2020 |
Antibiotics-driven gut microbiome perturbation alters immunity to vaccines in humans T Hagan, M Cortese, N Rouphael, C Boudreau, C Linde, MS Maddur, ... Cell 178 (6), 1313-1328. e13, 2019 | 454 | 2019 |
Systems vaccinology of the BNT162b2 mRNA vaccine in humans PS Arunachalam, MKD Scott, T Hagan, C Li, Y Feng, F Wimmers, ... Nature 596 (7872), 410-416, 2021 | 365 | 2021 |
Systems analysis of immunity to influenza vaccination across multiple years and in diverse populations reveals shared molecular signatures HI Nakaya, T Hagan, SS Duraisingham, EK Lee, M Kwissa, N Rouphael, ... Immunity 43 (6), 1186-1198, 2015 | 299 | 2015 |
Metabolic phenotypes of response to vaccination in humans S Li, NL Sullivan, N Rouphael, T Yu, S Banton, MS Maddur, ... Cell 169 (5), 862-877. e17, 2017 | 249 | 2017 |
The single-cell epigenomic and transcriptional landscape of immunity to influenza vaccination F Wimmers, M Donato, A Kuo, T Ashuach, S Gupta, C Li, M Dvorak, ... Cell 184 (15), 3915-3935. e21, 2021 | 151 | 2021 |
Systems vaccinology: enabling rational vaccine design with systems biological approaches T Hagan, HI Nakaya, S Subramaniam, B Pulendran Vaccine 33 (40), 5294-5301, 2015 | 119 | 2015 |
mTOR regulates metabolic adaptation of APCs in the lung and controls the outcome of allergic inflammation C Sinclair, G Bommakanti, L Gardinassi, J Loebbermann, MJ Johnson, ... Science 357 (6355), 1014-1021, 2017 | 109 | 2017 |
Engineering cell–material interfaces for long-term expansion of human pluripotent stem cells CW Chang, Y Hwang, D Brafman, T Hagan, C Phung, S Varghese Biomaterials 34 (4), 912-921, 2013 | 66 | 2013 |
Pan-vaccine analysis reveals innate immune endotypes predictive of antibody responses to vaccination S Fourati, LE Tomalin, MP Mulè, DG Chawla, B Gerritsen, D Rychkov, ... Nature Immunology 23 (12), 1777-1787, 2022 | 55* | 2022 |
Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses T Hagan, B Gerritsen, LE Tomalin, S Fourati, MP Mulè, DG Chawla, ... Nature immunology 23 (12), 1788-1798, 2022 | 47 | 2022 |
Will systems biology deliver its promise and contribute to the development of new or improved vaccines? From data to understanding through systems biology T Hagan, B Pulendran Cold Spring Harbor perspectives in biology 10 (8), a028894, 2018 | 36 | 2018 |
Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: results from the IMPACC study A Ozonoff, J Schaenman, ND Jayavelu, CE Milliren, CS Calfee, CB Cairns, ... EBioMedicine 83, 2022 | 32 | 2022 |
Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity TY Shao, P Kakade, JN Witchley, C Frazer, KL Murray, IV Ene, ... Cell reports 39 (7), 2022 | 19 | 2022 |
SREBP signaling is essential for effective B cell responses W Luo, JZ Adamska, C Li, R Verma, Q Liu, T Hagan, F Wimmers, S Gupta, ... Nature immunology 24 (2), 337-348, 2023 | 18 | 2023 |
The immune signatures data resource, a compendium of systems vaccinology datasets J Diray-Arce, HER Miller, E Henrich, B Gerritsen, MP Mulè, S Fourati, ... Scientific Data 9 (1), 635, 2022 | 16 | 2022 |
Multi-omics analysis of mucosal and systemic immunity to SARS-CoV-2 after birth F Wimmers, AR Burrell, Y Feng, H Zheng, PS Arunachalam, M Hu, ... Cell 186 (21), 4632-4651. e23, 2023 | 6* | 2023 |
DTI connectometry analysis reveals white matter changes in cognitively impaired World Trade Center responders at midlife M Kritikos, C Huang, SAP Clouston, AC Pellecchia, S Santiago-Michels, ... Journal of Alzheimer's Disease 89 (3), 1075-1089, 2022 | 5 | 2022 |
World trade center site exposure duration is associated with hippocampal and cerebral white matter neuroinflammation C Huang, M Kritikos, MS Sosa, T Hagan, A Domkan, J Meliker, ... Molecular neurobiology 60 (1), 160-170, 2023 | 4 | 2023 |
Ablation of Adar1 in myeloid cells imprints a global antiviral state in the lung and heightens early immunity against SARS-CoV-2 JZ Adamska, R Verma, S Gupta, T Hagan, F Wimmers, K Floyd, Q Li, ... Cell reports 42 (1), 2023 | 1 | 2023 |