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Jordan Rossen
Jordan Rossen
Department of Epidemiology, Harvard T.H. Chan School of Public Health
Adresse e-mail validée de g.harvard.edu
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Année
Copper induces cell death by targeting lipoylated TCA cycle proteins
P Tsvetkov, S Coy, B Petrova, M Dreishpoon, A Verma, M Abdusamad, ...
Science 375 (6586), 1254-1261, 2022
18552022
Discovering the anticancer potential of non-oncology drugs by systematic viability profiling
SM Corsello, RT Nagari, RD Spangler, J Rossen, M Kocak, JG Bryan, ...
Nature cancer 1 (2), 235-248, 2020
5092020
Mitochondrial metabolism promotes adaptation to proteotoxic stress
P Tsvetkov, A Detappe, K Cai, HR Keys, Z Brune, W Ying, P Thiru, ...
Nature chemical biology 15 (7), 681-689, 2019
3272019
Extracting biological insights from the project achilles genome-scale CRISPR screens in cancer cell lines
JM Dempster, J Rossen, M Kazachkova, J Pan, G Kugener, DE Root, ...
BioRxiv, 720243, 2019
2912019
Non-oncology drugs are a source of previously unappreciated anti-cancer activity
SM Corsello, RT Nagari, RD Spangler, J Rossen, M Kocak, JG Bryan, ...
BioRxiv, 730119, 2019
352019
Discovering the anti-cancer potential of non-oncology drugs by systematic viability profiling. Nat Cancer. 2020; 1: 235–48
SM Corsello, RT Nagari, RD Spangler, J Rossen, M Kocak, JG Bryan
62022
Adenosine receptor antagonists exhibit potent and selective off-target killing of FOXA1-high cancers
SM Corsello, RD Spangler, R Humeidi, CN Harrington, RT Nagari, ...
Cancer Research 80 (16_Supplement), 3400-3400, 2020
12020
Abstract B121: An oncogene-linked prodrug strategy in lung cancer
A Boudreau, J Roth, J Rong, N Olsson, C Mader, J Byran, J Rossen, ...
Molecular Cancer Therapeutics 18 (12_Supplement), B121-B121, 2019
2019
Mitochondrial metabolism promotes adaptation to proteotoxic stress (vol 15, pg 681, 2019)
P Tsvetkov, A Detappe, K Cai, HR Keys, Z Brune, W Ying, P Thiru, ...
NATURE CHEMICAL BIOLOGY 15 (7), 757-757, 2019
2019
Massively parallel multiplexed methods to screen hundreds of barcoded cancer cell line models with small molecules or genetic perturbations using next-generation sequencing
S Bender, C Zhu, L Wang, M Rothberg, J Dempster, B Paolella, M Kocak, ...
Cancer Research 79 (13_Supplement), 2690-2690, 2019
2019
Novel cell line barcoding method reveals tepoxalin as a selective drug against MDR1-high tumor cells
SM Corsello, RD Spangler, RT Nagari, M Kocak, J Rossen, P O'Hearn, ...
Cancer Research 79 (13_Supplement), 2948-2948, 2019
2019
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