Enhanced detection of circulating tumor DNA by fragment size analysis F Mouliere, D Chandrananda, AM Piskorz, EK Moore, J Morris, ... Science translational medicine 10 (466), eaat4921, 2018 | 819 | 2018 |
Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy D Vilchez, S Ros, D Cifuentes, L Pujadas, J Vallès, B García-Fojeda, ... Nature neuroscience 10 (11), 1407-1413, 2007 | 430 | 2007 |
Balancing glycolytic flux: the role of 6-phosphofructo-2-kinase/fructose 2, 6-bisphosphatases in cancer metabolism S Ros, A Schulze Cancer & metabolism 1, 1-10, 2013 | 264 | 2013 |
Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth B Griffiths, CA Lewis, K Bensaad, S Ros, Q Zhang, EC Ferber, S Konisti, ... Cancer & metabolism 1, 1-21, 2013 | 256 | 2013 |
Functional metabolic screen identifies 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 4 as an important regulator of prostate cancer cell survival S Ros, CR Santos, S Moco, F Baenke, G Kelly, M Howell, N Zamboni, ... Cancer discovery 2 (4), 328-343, 2012 | 224 | 2012 |
Regulation of glycogen synthesis by the laforin–malin complex is modulated by the AMP-activated protein kinase pathway MC Solaz-Fuster, JV Gimeno-Alcaniz, S Ros, ME Fernandez-Sanchez, ... Human molecular genetics 17 (5), 667-678, 2008 | 163 | 2008 |
Functional screening identifies MCT4 as a key regulator of breast cancer cell metabolism and survival F Baenke, S Dubuis, C Brault, B Weigelt, B Dankworth, B Griffiths, M Jiang, ... The Journal of pathology 237 (2), 152-165, 2015 | 97 | 2015 |
MRI measurements of reporter-mediated increases in transmembrane water exchange enable detection of a gene reporter F Schilling, S Ros, DE Hu, P D'Santos, S McGuire, R Mair, AJ Wright, ... Nature biotechnology 35 (1), 75-80, 2017 | 75 | 2017 |
Control of liver glycogen synthase activity and intracellular distribution by phosphorylation S Ros, M García-Rocha, J Domínguez, JC Ferrer, JJ Guinovart Journal of Biological Chemistry 284 (10), 6370-6378, 2009 | 71 | 2009 |
6-Phosphofructo-2-kinase/fructose-2, 6-biphosphatase 4 is essential for p53-null cancer cells S Ros, J Flöter, I Kaymak, C Da Costa, A Houddane, S Dubuis, B Griffiths, ... Oncogene 36 (23), 3287-3299, 2017 | 69 | 2017 |
Glycolysis back in the limelight: systemic targeting of HK2 blocks tumor growth S Ros, A Schulze Cancer discovery 3 (10), 1105-1107, 2013 | 57 | 2013 |
Metabolic imaging detects resistance to PI3Kα inhibition mediated by persistent FOXM1 expression in ER+ breast cancer S Ros, AJ Wright, P D'Santos, D Hu, RL Hesketh, Y Lubling, ... Cancer Cell 38 (4), 516-533. e9, 2020 | 47 | 2020 |
The role of transmembrane protein 27 (TMEM27) in islet physiology and its potential use as a beta cell mass biomarker J Altirriba, R Gasa, S Casas, MJ Ramirez-Bajo, S Ros, ... Diabetologia 53, 1406-1414, 2010 | 45 | 2010 |
Magnetic resonance imaging is more sensitive than PET for detecting treatment-induced cell death–dependent changes in glycolysis RL Hesketh, J Wang, AJ Wright, DY Lewis, AE Denton, R Grenfell, ... Cancer research 79 (14), 3557-3569, 2019 | 43 | 2019 |
Breast cancer–associated macrophages promote tumorigenesis by suppressing succinate dehydrogenase in tumor cells V Gómez, TR Eykyn, R Mustapha, F Flores-Borja, V Male, PR Barber, ... Science signaling 13 (652), eaax4585, 2020 | 41 | 2020 |
Metabolic imaging detects low levels of glycolytic activity that vary with levels of c-Myc expression in patient-derived xenograft models of glioblastoma R Mair, AJ Wright, S Ros, D Hu, T Booth, F Kreis, J Rao, C Watts, ... Cancer research 78 (18), 5408-5418, 2018 | 39 | 2018 |
Restoration of hepatic glycogen deposition reduces hyperglycaemia, hyperphagia and gluconeogenic enzymes in a streptozotocin-induced model of diabetes in rats S Ros, M Garcia-Rocha, J Calbo, JJ Guinovart Diabetologia 54, 2639-2648, 2011 | 36 | 2011 |
Linking glycogen and senescence in cancer cells S Ros, A Schulze Cell metabolism 16 (6), 687-688, 2012 | 35 | 2012 |
Hepatic overexpression of a constitutively active form of liver glycogen synthase improves glucose homeostasis S Ros, D Zafra, J Valles-Ortega, M García-Rocha, S Forrow, J Domínguez, ... Journal of biological chemistry 285 (48), 37170-37177, 2010 | 34 | 2010 |
Selecting short DNA fragments in plasma improves detection of circulating tumour DNA F Mouliere, AM Piskorz, D Chandrananda, E Moore, J Morris, CG Smith, ... BioRxiv, 134437, 2017 | 33 | 2017 |