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harlan r barker
harlan r barker
Tampere University
Verified email at tuni.fi - Homepage
Title
Cited by
Cited by
Year
Chromatin accessibility is associated with CRISPR-Cas9 efficiency in the zebrafish (Danio rerio)
MIE Uusi-Mäkelä, HR Barker, CA Bäuerlein, T Häkkinen, M Nykter, ...
PloS one 13 (4), e0196238, 2018
1052018
Zebrafish as a model organism for the development of drugs for skin cancer
F Bootorabi, H Manouchehri, R Changizi, H Barker, E Palazzo, A Saltari, ...
International journal of molecular sciences 18 (7), 1550, 2017
662017
Carbonic anhydrases in metazoan model organisms: molecules, mechanisms, and physiology
A Aspatwar, MEE Tolvanen, H Barker, L Syrjänen, S Valanne, ...
Physiological reviews 102 (3), 1327-1383, 2022
482022
Wnt5a and ROR1 activate non-canonical Wnt signaling via RhoA in TCF3-PBX1 acute lymphoblastic leukemia and highlight new treatment strategies via Bcl-2 co-targeting
H Karvonen, R Perttilä, W Niininen, V Hautanen, H Barker, A Murumägi, ...
Oncogene 38 (17), 3288-3300, 2019
482019
Drosophila melanogaster: a model organism for controlling Dipteran vectors and pests
R Zolfaghari Emameh, L Syrjänen, H Barker, CT Supuran, S Parkkila
Journal of Enzyme Inhibition and Medicinal Chemistry 30 (3), 505-513, 2015
462015
Bioinformatic analysis of beta carbonic anhydrase sequences from protozoans and metazoans
R Zolfaghari Emameh, H Barker, MEE Tolvanen, C Ortutay, S Parkkila
Parasites & vectors 7, 1-12, 2014
442014
Bioinformatic characterization of angiotensin-converting enzyme 2, the entry receptor for SARS-CoV-2
H Barker, S Parkkila
PLoS One 15 (10), e0240647, 2020
432020
Glucocorticoids induce differentiation and chemoresistance in ovarian cancer by promoting ROR1-mediated stemness
H Karvonen, M Arjama, L Kaleva, W Niininen, H Barker, ...
Cell death & disease 11 (9), 790, 2020
432020
β-CA-specific inhibitor dithiocarbamate Fc14–584B: a novel antimycobacterial agent with potential to treat drug-resistant tuberculosis
A Aspatwar, M Hammarén, S Koskinen, B Luukinen, H Barker, F Carta, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 32 (1), 832-840, 2017
422017
Molecular mechanisms associated with ROR1-mediated drug resistance: crosstalk with Hippo-YAP/TAZ and BMI-1 pathways
H Karvonen, H Barker, L Kaleva, W Niininen, D Ungureanu
Cells 8 (8), 812, 2019
402019
Role of carbonic anhydrases in skin wound healing
H Barker, M Aaltonen, P Pan, M Vähätupa, P Kaipiainen, U May, S Prince, ...
Experimental & Molecular Medicine 49 (5), e334-e334, 2017
372017
Beta carbonic anhydrases: novel targets for pesticides and anti-parasitic agents in agriculture and livestock husbandry
R Zolfaghari Emameh, H Barker, VP Hytönen, MEE Tolvanen, S Parkkila
Parasites & vectors 7, 1-11, 2014
352014
Ascaris lumbricoides β carbonic anhydrase: a potential target enzyme for treatment of ascariasis
R Zolfaghari Emameh, M Kuuslahti, D Vullo, HR Barker, CT Supuran, ...
Parasites & Vectors 8, 1-10, 2015
332015
Horizontal transfer of β-carbonic anhydrase genes from prokaryotes to protozoans, insects, and nematodes
R Zolfaghari Emameh, HR Barker, MEE Tolvanen, S Parkkila, VP Hytönen
Parasites & vectors 9, 1-12, 2016
262016
Design, synthesis, in vitro inhibition and toxicological evaluation of human carbonic anhydrases I, II and IX inhibitors in 5-nitroimidazole series
A Aspatwar, NK Parvathaneni, H Barker, E Anduran, CT Supuran, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 35 (1), 109-117, 2020
232020
Identification and inhibition of carbonic anhydrases from nematodes
R Zolfaghari Emameh, HR Barker, L Syrjänen, L Urbański, CT Supuran, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 31 (sup4), 176-184, 2016
232016
Inactivation of ca10a and ca10b Genes Leads to Abnormal Embryonic Development and Alters Movement Pattern in Zebrafish
A Aspatwar, MEE Tolvanen, MJT Ojanen, HR Barker, AK Saralahti, ...
PLoS One 10 (7), e0134263, 2015
222015
Analysis of evolution of carbonic anhydrases IV and XV reveals a rich history of gene duplications and a new group of isozymes
MEE Tolvanen, C Ortutay, HR Barker, A Aspatwar, M Patrikainen, ...
Bioorganic & medicinal chemistry 21 (6), 1503-1510, 2013
222013
Nitroimidazole-based inhibitors DTP338 and DTP348 are safe for zebrafish embryos and efficiently inhibit the activity of human CA IX in Xenopus oocytes
A Aspatwar, HM Becker, NK Parvathaneni, M Hammaren, A Svorjova, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 33 (1), 1064-1073, 2018
182018
Targeting Wnt signaling pseudokinases in hematological cancers
H Karvonen, R Perttilä, W Niininen, H Barker, D Ungureanu
European Journal of Haematology 101 (4), 457-465, 2018
162018
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