RNA m6A methylation regulates sorafenib resistance in liver cancer through FOXO3‐mediated autophagy Z Lin, Y Niu, A Wan, D Chen, H Liang, X Chen, L Sun, S Zhan, L Chen, ... The EMBO journal 39 (12), e103181, 2020 | 303 | 2020 |
Necroptosis: an alternative cell death program defending against cancer D Chen, J Yu, L Zhang Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1865 (2), 228-236, 2016 | 193 | 2016 |
PUMA amplifies necroptosis signaling by activating cytosolic DNA sensors D Chen, J Tong, L Yang, L Wei, DB Stolz, J Yu, J Zhang, L Zhang Proceedings of the National Academy of Sciences 115 (15), 3930-3935, 2018 | 149 | 2018 |
Mcl-1 degradation is required for targeted therapeutics to eradicate colon cancer cells J Tong, P Wang, S Tan, D Chen, Z Nikolovska-Coleska, F Zou, J Yu, ... Cancer research 77 (9), 2512-2521, 2017 | 134 | 2017 |
Regorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis D Chen, L Wei, J Yu, L Zhang Clinical cancer research 20 (13), 3472-3484, 2014 | 117 | 2014 |
Effects of Cu2O nanoparticle and CuCl2 on zebrafish larvae and a liver cell-line D Chen, D Zhang, CY Jimmy, KM Chan Aquatic toxicology 105 (3-4), 344-354, 2011 | 100 | 2011 |
RNA-binding protein RALY reprogrammes mitochondrial metabolism via mediating miRNA processing in colorectal cancer L Sun, A Wan, Z Zhou, D Chen, H Liang, C Liu, S Yan, Y Niu, Z Lin, ... Gut 70 (9), 1698-1712, 2021 | 72 | 2021 |
Loss‐of‐function genetic screening identifies aldolase a as an essential driver for liver cancer cell growth under hypoxia Y Niu, Z Lin, A Wan, L Sun, S Yan, H Liang, S Zhan, D Chen, X Bu, P Liu, ... Hepatology 74 (3), 1461-1479, 2021 | 64 | 2021 |
p53 up‐regulated modulator of apoptosis induction mediates acetaminophen‐induced necrosis and liver injury in mice D Chen, HM Ni, L Wang, X Ma, J Yu, WX Ding, L Zhang Hepatology 69 (5), 2164-2179, 2019 | 62 | 2019 |
Fibulin-5 inhibits Wnt/β-catenin signaling in lung cancer X Chen, X Song, W Yue, D Chen, J Yu, Z Yao, L Zhang Oncotarget 6 (17), 15022, 2015 | 60 | 2015 |
BRAFV600E-dependent Mcl-1 stabilization leads to everolimus resistance in colon cancer cells K He, D Chen, H Ruan, X Li, J Tong, X Xu, L Zhang, J Yu Oncotarget 7 (30), 47699, 2016 | 59 | 2016 |
Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis MF Brown, BJ Leibowitz, D Chen, K He, F Zou, RW Sobol, D Beer-Stolz, ... Cell death & disease 6 (4), e1729-e1729, 2015 | 52 | 2015 |
Differentially expressed proteins in zebrafish liver cells exposed to copper DS Chen, KM Chan Aquatic toxicology 104 (3-4), 270-277, 2011 | 44 | 2011 |
Aurora kinase inhibition induces PUMA via NF-κB to kill colon cancer cells J Sun, K Knickelbein, K He, D Chen, C Dudgeon, Y Shu, J Yu, L Zhang Molecular cancer therapeutics 13 (5), 1298-1308, 2014 | 42 | 2014 |
RIP3-dependent necroptosis contributes to the pathogenesis of chronic obstructive pulmonary disease D Chen, AD Gregory, X Li, J Wei, CL Burton, G Gibson, SJ Scott, ... JCI insight 6 (12), 2021 | 36 | 2021 |
TAp73 promotes cell survival upon genotoxic stress by inhibiting p53 activity D Chen, L Ming, F Zou, Y Peng, B Van Houten, J Yu, L Zhang Oncotarget 5 (18), 8107, 2014 | 32 | 2014 |
Restoring PUMA induction overcomes KRAS-mediated resistance to anti-EGFR antibodies in colorectal cancer K Knickelbein, J Tong, D Chen, YJ Wang, S Misale, A Bardelli, J Yu, ... Oncogene 37 (33), 4599-4610, 2018 | 30 | 2018 |
Understanding copper sensitivity in zebrafish (Danio rerio) through the intracellular localization of copper transporters in a hepatocyte cell-line ZFL and the tissue … KP Leung, D Chen, KM Chan Metallomics 6 (5), 1057-1067, 2014 | 28 | 2014 |
Changes in the protein expression profiles of the Hepa-T1 cell line when exposed to Cu2+ DS Chen, KM Chan Aquatic toxicology 94 (3), 163-176, 2009 | 27 | 2009 |
Biokinetics of cadmium and zinc in a marine bacterium: influences of metal interaction and pre‐exposure D Chen, PY Qian, WX Wang Environmental Toxicology and Chemistry: An International Journal 27 (8 …, 2008 | 27 | 2008 |