Secondary structure reshuffling modulates glycosyltransferase function at the membrane D Giganti, D Albesa-Jové, S Urresti, A Rodrigo-Unzueta, MA Martínez, ... Nature Chemical Biology 11 (1), 16-18, 2015 | 55 | 2015 |
Rv2466c Mediates the Activation of TP053 To Kill Replicating and Non-replicating Mycobacterium tuberculosis D Albesa-Jove, LR Chiarelli, V Makarov, MR Pasca, S Urresti, G Mori, ... ACS Chemical Biology 9 (7), 1567-1575, 2014 | 45 | 2014 |
A native ternary complex trapped in a crystal reveals the catalytic mechanism of a retaining glycosyltransferase D Albesa‐Jové, F Mendoza, A Rodrigo‐Unzueta, F Gomollón‐Bel, ... Angewandte Chemie International Edition 54 (34), 9898-9902, 2015 | 44 | 2015 |
Structural basis of glycogen metabolism in bacteria JO Cifuente, N Comino, B Trastoy, C D'Angelo, ME Guerin Biochemical Journal 476 (14), 2059-2092, 2019 | 35 | 2019 |
DESign of Sustainable One-Pot Chemoenzymatic Organic Transformations in Deep Eutectic Solvents for the Synthesis of 1,2-Disubstituted Aromatic Olefins N Ríos-Lombardía, MJ Rodríguez-Álvarez, F Morís, R Kourist, N Comino, ... Frontiers in Chemistry 8, 139, 2020 | 31 | 2020 |
Intraparticle kinetics unveil crowding and enzyme distribution effects on the performance of cofactor-dependent heterogeneous biocatalysts E Diamanti, J Santiago-Arcos, D Grajales-Hernández, N Czarnievicz, ... ACS catalysis 11 (24), 15051-15067, 2021 | 30 | 2021 |
Conformational plasticity of the essential membrane-associated mannosyltransferase PimA from mycobacteria D Giganti, J Alegre-Cebollada, S Urresti, D Albesa-Jové, ... Journal of Biological Chemistry 288 (41), 29797-29808, 2013 | 30 | 2013 |
Structural basis of glycogen biosynthesis regulation in bacteria JO Cifuente, N Comino, J Madariaga-Marcos, S López-Fernández, ... Structure 24 (9), 1613-1622, 2016 | 28 | 2016 |
The redox state regulates the conformation of Rv2466c to activate the antitubercular prodrug TP053 D Albesa-Jové, N Comino, M Tersa, E Mohorko, S Urresti, E Dainese, ... Journal of Biological Chemistry 290 (52), 31077-31089, 2015 | 22 | 2015 |
Intraparticle macromolecular migration alters the structure and function of proteins reversibly immobilized on porous microbeads E Diamanti, S Arana‐Peña, P Ramos‐Cabrer, N Comino, D Carballares, ... Advanced Materials Interfaces 9 (18), 2200263, 2022 | 21 | 2022 |
Molecular basis of membrane association by the phosphatidylinositol mannosyltransferase PimA enzyme from mycobacteria A Rodrigo-Unzueta, MA Martínez, N Comino, PM Alzari, A Chenal, ... Journal of Biological Chemistry 291 (27), 13955-13963, 2016 | 21 | 2016 |
Mechanistic insights into the allosteric regulation of bacterial ADP-glucose pyrophosphorylases N Comino, JO Cifuente, A Marina, A Orrantia, A Eguskiza, ME Guerin Journal of Biological Chemistry 292 (15), 6255-6268, 2017 | 16 | 2017 |
Structural snapshots and loop dynamics along the catalytic cycle of glycosyltransferase GpgS D Albesa-Jové, J Romero-García, E Sancho-Vaello, FX Contreras, ... Structure 25 (7), 1034-1044. e3, 2017 | 15 | 2017 |
Microcompartmentalized cell-free protein synthesis in hydrogel μ-channels AI Benítez-Mateos, N Zeballos, N Comino, L Moreno de Redrojo, ... ACS Synthetic Biology 9 (11), 2971-2978, 2020 | 8 | 2020 |
Dissecting the structural and chemical determinants of the “open-to-closed” motion in the mannosyltransferase PimA from mycobacteria A Rodrigo-Unzueta, M Ghirardello, S Urresti, I Delso, D Giganti, I Anso, ... Biochemistry 59 (32), 2934-2945, 2020 | 8 | 2020 |
The allosteric control mechanism of bacterial glycogen biosynthesis disclosed by cryoEM JO Cifuente, N Comino, C D'Angelo, A Marina, D Gil-Carton, ... Current Research in Structural Biology 2, 89-103, 2020 | 4 | 2020 |
Region-directed enzyme immobilization through engineering protein surface with histidine clusters N Zeballos, N Comino, D Andrés-Sanz, J Santiago-Arcos, M Azkargorta, ... ACS Applied Materials & Interfaces 16 (1), 833-846, 2023 | 2 | 2023 |
In-Hydrogel Cell-Free Protein Expression System as Biocompatible and Implantable Biomaterial M Sánchez-Costa, A Urigoitia, N Comino, B Arnaiz, N Khatami, ... ACS Applied Materials & Interfaces 16 (13), 15993-16002, 2024 | | 2024 |
MOLECULAR BASIS OF MEMBRANE ASSOCIATION BY THE PHOSPHATIDYLINOSITOL MANNOSYLTRANSFERASE PIMA FROM MYCOBACTERIA AR Unzueta, MA Martínez, N Comino, PM Alzari, A Chenal, ME Guerin | | 2016 |