Aberrant GLI1 activation in DNA damage response, carcinogenesis and chemoresistance K Palle, C Mani, K Tripathi, M Athar Cancers 7 (4), 2330-2351, 2015 | 86 | 2015 |
RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance RR Somasagara, SM Spencer, K Tripathi, DW Clark, C Mani, ... Oncogene 36 (48), 6680-6690, 2017 | 65 | 2017 |
Prexasertib treatment induces homologous recombination deficiency and synergizes with olaparib in triple-negative breast cancer cells C Mani, S Jonnalagadda, J Lingareddy, S Awasthi, WH Gmeiner, K Palle Breast Cancer Research 21, 1-14, 2019 | 54 | 2019 |
Gli1 protein regulates the S-phase checkpoint in tumor cells via Bid protein, and its inhibition sensitizes to DNA topoisomerase 1 inhibitors K Tripathi, C Mani, R Barnett, S Nalluri, L Bachaboina, RP Rocconi, ... Journal of Biological Chemistry 289 (45), 31513-31525, 2014 | 51 | 2014 |
Bleomycin, neocarzinostatin and ionising radiation-induced bystander effects in normal diploid human lung fibroblasts, bone marrow mesenchymal stem cells, lung adenocarcinoma … M Chinnadurai, S Chidambaram, V Ganesan, U Baraneedharan, ... International Journal of Radiation Biology 87 (7), 673-682, 2011 | 41 | 2011 |
DNA repair fidelity in stem cell maintenance, health, and disease C Mani, PH Reddy, K Palle Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (4), 165444, 2020 | 39 | 2020 |
Rad18 is required for functional interactions between FANCD2, BRCA2, and Rad51 to repair DNA topoisomerase 1-poisons induced lesions and promote fork recovery K Tripathi, C Mani, DW Clark, K Palle Oncotarget 7 (11), 12537, 2016 | 38 | 2016 |
γ-H2AX assay: a technique to quantify DNA double strand breaks I Rakiman, M Chinnadurai, U Baraneedharan, SFD Paul, ... Advanced Biotech, 39-41, 2008 | 28 | 2008 |
The effect of growth architecture on the induction and decay of bleomycin and X-ray-induced bystander response and genomic instability in lung adenocarcinoma cells and blood … M Chinnadurai, SFD Paul, P Venkatachalam International Journal of Radiation Biology 89 (2), 69-78, 2013 | 26 | 2013 |
Detection and evaluation of estrogen DNA‐adducts and their carcinogenic effects in cultured human cells using biotinylated estradiol K Tripathi, C Mani, RR Somasagara, DW Clark, V Ananthapur, K Vinaya, ... Molecular carcinogenesis 56 (3), 1010-1020, 2017 | 25 | 2017 |
Human brain glioblastoma cells do not induce but do respond to the bleomycin-induced bystander response from lung adenocarcinoma cells SAS Basheerudeen, C Mani, MAK Kulkarni, K Pillai, A Rajan, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 757 (2 …, 2013 | 23 | 2013 |
The multifunctional protein PACS-1 is required for HDAC2-and HDAC3-dependent chromatin maturation and genomic stability C Mani, K Tripathi, S Luan, DW Clark, JF Andrews, A Vindigni, G Thomas, ... Oncogene 39 (12), 2583-2596, 2020 | 19 | 2020 |
Role of reactive oxygen species and nitric oxide in mediating chemotherapeutic drug induced bystander response in human cancer cells exposed in-vitro M Chinnadurai, BS Rao, R Deepika, SFD Paul, P Venkatachalam World Journal of Oncology 3 (2), 64, 2012 | 19 | 2012 |
Renal lipid metabolism abnormalities in obesity and clear cell renal cell carcinoma IA Bobulescu, LM Pop, C Mani, K Turner, C Rivera, S Khatoon, ... Metabolites 11 (9), 608, 2021 | 16 | 2021 |
Protective effect of a polyherbal aqueous extract comprised of Nigella sativa (seeds), Hemidesmus indicus (roots), and Smilax glabra (rhizome) on bleomycin induced cytogenetic … BP Galhena, SSR Samarakoon, MI Thabrew, SFD Paul, V Perumal, ... BioMed Research International 2017, 2017 | 16 | 2017 |
Thymineless death by the fluoropyrimidine polymer F10 involves replication fork collapse and is enhanced by Chk1 inhibition C Mani, S Pai, CM Papke, K Palle, WH Gmeiner Neoplasia 20 (12), 1236-1245, 2018 | 14 | 2018 |
GLI1-targeting drugs induce replication stress and homologous recombination deficiency and synergize with PARP-targeted therapies in triple negative breast cancer cells C Mani, K Tripathi, TR Omy, M Reedy, U Manne, K Palle Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1868 (2), 166300, 2022 | 9 | 2022 |
Improved antitumor activity of the fluoropyrimidine polymer CF10 in preclinical colorectal cancer models through distinct mechanistic and pharmacologic properties WH Gmeiner, A Dominijanni, AO Haber, LP Ghiraldeli, DL Caudell, ... Molecular cancer therapeutics 20 (3), 553-563, 2021 | 9 | 2021 |
Synthesis and biological evaluation of N, N-dialkylcarboxy coumarin-NO donor conjugates as potential anticancer agents GL Nelson, CT Ronayne, LN Solano, SK Jonnalagadda, S Jonnalagadda, ... Bioorganic & Medicinal Chemistry Letters 52, 128411, 2021 | 8 | 2021 |
AraC-FdUMP[10] Is a Next-Generation Fluoropyrimidine with Potent Antitumor Activity in PDAC and Synergy with PARG Inhibition AO Haber, A Jain, C Mani, A Nevler, LC Agostini, T Golan, K Palle, ... Molecular Cancer Research 19 (4), 565-572, 2021 | 7 | 2021 |