| Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor V Rothhammer, ID Mascanfroni, L Bunse, MC Takenaka, JE Kenison, ... Nature medicine 22 (6), 586-597, 2016 | 1159 | 2016 |
| RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS Y Ito, D Ofengeim, A Najafov, S Das, S Saberi, Y Li, J Hitomi, H Zhu, ... Science 353 (6299), 603-608, 2016 | 520 | 2016 |
| Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation L Mayo, SA Trauger, M Blain, M Nadeau, B Patel, JI Alvarez, ... Nature medicine 20 (10), 1147-1156, 2014 | 432 | 2014 |
| Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39 MC Takenaka, G Gabriely, V Rothhammer, ID Mascanfroni, MA Wheeler, ... Nature neuroscience 22 (5), 729-740, 2019 | 372 | 2019 |
| IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39 ID Mascanfroni, A Yeste, SM Vieira, EJ Burns, B Patel, I Sloma, Y Wu, ... Nature immunology 14 (10), 1054-1063, 2013 | 370 | 2013 |
| The innate immune system in demyelinating disease L Mayo, FJ Quintana, HL Weiner Immunological reviews 248 (1), 170-187, 2012 | 229 | 2012 |
| Dissection of influenza infection in vivo by single-cell RNA sequencing Y Steuerman, M Cohen, N Peshes-Yaloz, L Valadarsky, O Cohn, E David, ... Cell systems 6 (6), 679-691. e4, 2018 | 188 | 2018 |
| Metabolic control of astrocyte pathogenic activity via cPLA2-MAVS CC Chao, C Gutiérrez-Vázquez, V Rothhammer, L Mayo, MA Wheeler, ... Cell 179 (7), 1483-1498. e22, 2019 | 138 | 2019 |
| Dual role of CD38 in microglial activation and activation-induced cell death L Mayo, J Jacob-Hirsch, N Amariglio, G Rechavi, MJ Moutin, FE Lund, ... The Journal of Immunology 181 (1), 92-103, 2008 | 112 | 2008 |
| IL-10-dependent Tr1 cells attenuate astrocyte activation and ameliorate chronic central nervous system inflammation L Mayo, APD Cunha, A Madi, V Beynon, Z Yang, JI Alvarez, A Prat, ... Brain 139 (7), 1939-1957, 2016 | 105 | 2016 |
| Cell composition analysis of bulk genomics using single-cell data A Frishberg, N Peshes-Yaloz, O Cohn, D Rosentul, Y Steuerman, ... Nature methods 16 (4), 327-332, 2019 | 103 | 2019 |
| Impaired glutamate recycling and GluN2B‐mediated neuronal calcium overload in mice lacking TGF‐β1 in the CNS T Koeglsperger, S Li, C Brenneis, JL Saulnier, L Mayo, Y Carrier, ... Glia 61 (6), 985-1002, 2013 | 72 | 2013 |
| Acute microglia ablation induces neurodegeneration in the somatosensory system SJ Rubino, L Mayo, I Wimmer, V Siedler, F Brunner, S Hametner, A Madi, ... Nature communications 9 (1), 4578, 2018 | 63 | 2018 |
| CD38 deficiency in the tumor microenvironment attenuates glioma progression and modulates features of tumor-associated microglia/macrophages A Levy, E Blacher, H Vaknine, FE Lund, R Stein, L Mayo Neuro-oncology 14 (8), 1037-1049, 2012 | 58 | 2012 |
| Reduced folate carrier gene silencing in multiple antifolate-resistant tumor cell lines is due to a simultaneous loss of function of multiple transcription factors but not … L Rothem, M Stark, Y Kaufman, L Mayo, YG Assaraf Journal of Biological Chemistry 279 (1), 374-384, 2004 | 56 | 2004 |
| CD38 facilitates recovery from traumatic brain injury A Levy, A Bercovich-Kinori, AG Alexandrovich, J Tsenter, V Trembovler, ... Journal of neurotrauma 26 (9), 1521-1533, 2009 | 48 | 2009 |
| Prophylactic TLR9 stimulation reduces brain metastasis through microglia activation A Benbenishty, M Gadrich, A Cottarelli, A Lubart, D Kain, M Amer, ... PLoS biology 17 (3), e2006859, 2019 | 41 | 2019 |
| Characterization of LPS and interferon-γ triggered activation-induced cell death in N9 and primary microglial cells: Induction of the mitochondrial gateway by nitric oxide L Mayo, R Stein Cell Death & Differentiation 14 (1), 183-186, 2007 | 40 | 2007 |
| Astrocyte immunometabolic regulation of the tumour microenvironment drives glioblastoma pathogenicity R Perelroizen, B Philosof, N Budick-Harmelin, T Chernobylsky, A Ron, ... Brain 145 (9), 3288-3307, 2022 | 32 | 2022 |
| NAD+ metabolism drives astrocyte proinflammatory reprogramming in central nervous system autoimmunity T Meyer, D Shimon, S Youssef, G Yankovitz, A Tessler, T Chernobylsky, ... Proceedings of the National Academy of Sciences 119 (35), e2211310119, 2022 | 20 | 2022 |
Francisco J. QuintanaBrigham and Women's Hospital, Harvard Medical SchoolVerified email at rics.bwh.harvard.edu
