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Kathrin Bernt
Kathrin Bernt
Children's Hospital of Philadelphia
Verified email at email.chop.edu
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Cited by
Year
Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor
SR Daigle, EJ Olhava, CA Therkelsen, CR Majer, CJ Sneeringer, J Song, ...
Cancer cell 20 (1), 53-65, 2011
10022011
MLL-Rearranged Leukemia Is Dependent on Aberrant H3K79 Methylation by DOT1L
KM Bernt, N Zhu, AU Sinha, S Vempati, J Faber, AV Krivtsov, Z Feng, ...
Cancer cell 20 (1), 66-78, 2011
9452011
Chromatin-modifying enzymes as modulators of reprogramming
TT Onder, N Kara, A Cherry, AU Sinha, N Zhu, KM Bernt, P Cahan, ...
Nature 483 (7391), 598, 2012
7592012
MLL-rearranged leukemias—an update on science and clinical approaches
AC Winters, KM Bernt
Frontiers in pediatrics 5, 4, 2017
4182017
Human milk as a carrier of biochemical messages
KM Bernt, WA Walker
Acta Paediatrica 88, 27-41, 1999
2311999
DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia
CW Chen, RP Koche, AU Sinha, AJ Deshpande, N Zhu, R Eng, ...
Nature medicine 21 (4), 335, 2015
2302015
A new group B adenovirus receptor is expressed at high levels on human stem and tumor cells
S Tuve, H Wang, C Ware, Y Liu, A Gaggar, K Bernt, D Shayakhmetov, ...
Journal of virology 80 (24), 12109-12120, 2006
1842006
D. 958 Shayakhmetov, Z. Li, R. Strauss, D. Stone, and A. Lieber. 2006. A new 959 group B adenovirus receptor is expressed at high levels on human stem and 960 tumor cells
S Tuve, H Wang, C Ware, Y Liu, A Gaggar, K Bernt
J Virol 80, 12109-20, 0
184*
AF10 Regulates Progressive H3K79 Methylation and HOX Gene Expression in Diverse AML Subtypes
AJ Deshpande, A Deshpande, AU Sinha, L Chen, J Chang, A Cihan, ...
Cancer cell 26 (6), 896-908, 2014
1822014
Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l
AJ Deshpande, L Chen, M Fazio, AU Sinha, KM Bernt, D Banka, S Dias, ...
Blood, blood-2012-11-465120, 2013
1782013
Current concepts in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia
KMMD Bernt, SPMD Hunger
Frontiers in oncology 4, 54, 2014
1612014
A tumor-targeted and conditionally replicating oncolytic adenovirus vector expressing TRAIL for treatment of liver metastases
P Sova, XW Ren, S Ni, KM Bernt, J Mi, N Kiviat, A Lieber
Molecular Therapy 9 (4), 496-509, 2004
1562004
Abrogation of MLL–AF10 and CALM–AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l
L Chen, AJ Deshpande, D Banka, KM Bernt, S Dias, C Buske, EJ Olhava, ...
Leukemia 27 (4), 813, 2013
1482013
Targeting epigenetic programs in MLL-rearranged leukemias
KM Bernt, SA Armstrong
ASH Education Program Book 2011 (1), 354-360, 2011
1272011
Evaluation of biodistribution and safety of adenovirus vectors containing group B fibers after intravenous injection into baboons
S Ni, K Bernt, A Gaggar, ZY Li, HP Kiem, A Lieber
Human gene therapy 16 (6), 664-677, 2005
1222005
Enzyme-activated prodrug therapy enhances tumor-specific replication of adenovirus vectors
KM Bernt, DS Steinwaerder, S Ni, ZY Li, SR Roffler, A Lieber
Cancer research 62 (21), 6089-6098, 2002
822002
Assessment of a combined, adenovirus-mediated oncolytic and immunostimulatory tumor therapy
KM Bernt, S Ni, AT Tieu, A Lieber
Cancer research 65 (10), 4343-4352, 2005
812005
The effect of sequestration by nontarget tissues on anti-tumor efficacy of systemically applied, conditionally replicating adenovirus vectors
KM Bernt, S Ni, ZY Li, DM Shayakhmetov, A Lieber
Molecular Therapy 8 (5), 746-755, 2003
772003
Leukemia stem cells and human acute lymphoblastic leukemia
KM Bernt, SA Armstrong
Seminars in hematology 46 (1), 33-38, 2009
722009
Ezh2 Controls an Early Hematopoietic Program and Growth and Survival Signaling in Early T Cell Precursor Acute Lymphoblastic Leukemia
E Danis, T Yamauchi, K Echanique, X Zhang, JN Haladyna, SS Riedel, ...
Cell reports 14 (8), 1953-1965, 2016
672016
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