| Human lung natural killer cells are predominantly comprised of highly differentiated hypofunctional CD69− CD56dim cells N Marquardt, E Kekäläinen, P Chen, E Kvedaraite, JN Wilson, ... Journal of allergy and clinical immunology 139 (4), 1321-1330. e4, 2017 | 138 | 2017 |
| IL-13 and IL-4, but not IL-5 nor IL-17A, induce hyperresponsiveness in isolated human small airways ML Manson, J Säfholm, A James, AK Johnsson, P Bergman, M Al-Ameri, ... Journal of Allergy and Clinical Immunology 145 (3), 808-817. e2, 2020 | 113 | 2020 |
| Phenoconversion of cytochrome P450 metabolism: a systematic review SD Klomp, ML Manson, HJ Guchelaar, JJ Swen Journal of Clinical Medicine 9 (9), 2890, 2020 | 108 | 2020 |
| Prostaglandin E2 inhibits mast cell–dependent bronchoconstriction in human small airways through the E prostanoid subtype 2 receptor J Säfholm, ML Manson, J Bood, I Delin, AC Orre, P Bergman, M Al-Ameri, ... Journal of Allergy and Clinical Immunology 136 (5), 1232-1239. e1, 2015 | 103 | 2015 |
| The bitter taste receptor (TAS2R) agonists denatonium and chloroquine display distinct patterns of relaxation of the guinea pig trachea V Pulkkinen, ML Manson, J Säfholm, M Adner, SE Dahlén American Journal of Physiology-Lung Cellular and Molecular Physiology 303 …, 2012 | 86 | 2012 |
| Distinct effects of inflammation on cytochrome P450 regulation and drug metabolism: lessons from experimental models and a potential role for pharmacogenetics LM de Jong, W Jiskoot, JJ Swen, ML Manson Genes 11 (12), 1509, 2020 | 76 | 2020 |
| Bitter taste receptor agonists mediate relaxation of human and rodent vascular smooth muscle ML Manson, J Säfholm, M Al-Ameri, P Bergman, AC Orre, K Swärd, ... European journal of pharmacology 740, 302-311, 2014 | 63 | 2014 |
| Long-Acting β2-Adrenoceptor Agonists Enhance Glucocorticoid Receptor (GR)–Mediated Transcription by Gene-Specific Mechanisms Rather Than Generic Effects via GR CF Rider, MO Altonsy, MM Mostafa, SV Shah, S Sasse, ML Manson, ... Molecular Pharmacology 94 (3), 1031-1046, 2018 | 27 | 2018 |
| Mannitol triggers mast cell–dependent contractions of human small bronchi and prostacyclin bronchoprotection J Säfholm, ML Manson, J Bood, M Al-Ameri, AC Orre, J Raud, SE Dahlén, ... Journal of Allergy and Clinical Immunology 144 (4), 984-992, 2019 | 17 | 2019 |
| The TLR7 agonist imiquimod induces bronchodilation via a nonneuronal TLR7-independent mechanism: a possible role for quinoline in airway dilation OJ Larsson, ML Manson, M Starkhammar, B Fuchs, M Adner, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 310 …, 2016 | 13 | 2016 |
| Airway smooth muscle as a target in asthma: new insights into bronchorelaxation and hyperreactivity M Manson PQDT-Global, 2015 | 3 | 2015 |
| The impact of CYP2C19 genotype on phenoconversion by concomitant medication LM de Jong, S Boussallami, E Sánchez-López, M Giera, ME Tushuizen, ... Frontiers in Pharmacology 14, 1201906, 2023 | 2 | 2023 |
| PRMT3 inhibitor SGC707 reduces triglyceride levels and induces pruritus in Western-type diet-fed LDL receptor knockout mice LM de Jong, Z Zhang, Y den Hartog, TJP Sijsenaar, R Martins Cardoso, ... Scientific Reports 12 (1), 483, 2022 | 2 | 2022 |
| Unraveling the effects of acute inflammation on pharmacokinetics: a model-based analysis focusing on renal glomerular filtration rate and cytochrome P450 3A4-mediated metabolism F Liu, LBS Aulin, ML Manson, EHJ Krekels, JGC van Hasselt European Journal of Drug Metabolism and Pharmacokinetics 48 (6), 623-631, 2023 | 1 | 2023 |
| A systematic review on disease‐drug‐drug interactions with immunomodulating drugs: A critical appraisal of risk assessment and drug labelling LM de Jong, SD Klomp, N Treijtel, R Rissmann, JJ Swen, ML Manson British Journal of Clinical Pharmacology 88 (10), 4387-4402, 2022 | 1 | 2022 |
| Bitter taste receptor agonists as a novel class of bronchodilators in guinea-pig and rat airways SE Dahlén, V Pulkkinen, J Säfholm, M Manson, M Adner B19. EMERGING INSIGHTS INTO ASTHMA GENOMICS, BIOMARKERS AND THERAPEUTICS …, 2011 | 1 | 2011 |
| CNS Viral Infections—What to Consider for Improving Drug Treatment: A Plea for Using Mathematical Modeling Approaches M Sun, ML Manson, T Guo, ECM de Lange CNS drugs, 1-25, 2024 | | 2024 |
| The CREB-Regulated Transcription Coactivators, CRTC2/3, Facilitate the Synergistic Induction of RGS2 by LABAs and Glucocorticoids in Human Bronchial Epithelial Cells ML Manson, Z Rojnik, K Thorn, C Karrman Mardh, R Newton B61. EPITHELIAL CELL BIOLOGY IN RESPIRATORY DISEASE, A3803-A3803, 2018 | | 2018 |
| Human lung NK cells are predominantly constituted by highly differentiated hypofunctional CD69 (-) CD56 (dim) cells N Marquardt, E Kekalainen, JN Wilson, MA Ivarsson, J Mjosberg, ... EUROPEAN JOURNAL OF IMMUNOLOGY 46, 67-68, 2016 | | 2016 |
| The bronchodilatory capacity of imiquimod: the existence of two mechanisms OJ Larsson, ML Manson, M Starkhammar, B Fuchs, M Adner, SK Georén, ... American Journal of Physiology-Lung Cellular and Molecular Physiology, 2016 | | 2016 |
Jesper SäfholmAssistant Professor, Karolinska InstitutetVerified email at safholm.com
