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Michael Christoph Haffner
Michael Christoph Haffner
Verified email at fredhutch.org
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Cited by
Cited by
Year
Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements
MC Haffner, MJ Aryee, A Toubaji, DM Esopi, R Albadine, B Gurel, ...
Nature genetics 42 (8), 668-675, 2010
6732010
Tracking the clonal origin of lethal prostate cancer
MC Haffner, T Mosbruger, DM Esopi, H Fedor, CM Heaphy, DA Walker, ...
The Journal of clinical investigation 123 (11), 4918-4922, 2013
5402013
miR-21: an androgen receptor–regulated microRNA that promotes hormone-dependent and hormone-independent prostate cancer growth
J Ribas, X Ni, M Haffner, EA Wentzel, AH Salmasi, WH Chowdhury, ...
Cancer research 69 (18), 7165-7169, 2009
4872009
Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers
MC Haffner, A Chaux, AK Meeker, DM Esopi, J Gerber, LG Pellakuru, ...
Oncotarget 2 (8), 627, 2011
4772011
DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity
S Yegnasubramanian, MC Haffner, Y Zhang, B Gurel, TC Cornish, Z Wu, ...
Cancer research 68 (21), 8954-8967, 2008
3382008
Prostate-specific membrane antigen expression in the neovasculature of gastric and colorectal cancers
MC Haffner, IE Kronberger, JS Ross, CE Sheehan, M Zitt, G Mühlmann, ...
Human pathology 40 (12), 1754-1761, 2009
2932009
DNA methylation alterations exhibit intraindividual stability and interindividual heterogeneity in prostate cancer metastases
MJ Aryee, W Liu, JC Engelmann, P Nuhn, M Gurel, MC Haffner, D Esopi, ...
Science translational medicine 5 (169), 169ra10-169ra10, 2013
2752013
Genomic and phenotypic heterogeneity in prostate cancer
MC Haffner, W Zwart, MP Roudier, LD True, WG Nelson, JI Epstein, ...
Nature Reviews Urology 18 (2), 79-92, 2021
2682021
Effect of bipolar androgen therapy for asymptomatic men with castration-resistant prostate cancer: results from a pilot clinical study
MT Schweizer, ES Antonarakis, H Wang, AS Ajiboye, A Spitz, H Cao, ...
Science translational medicine 7 (269), 269ra2-269ra2, 2015
2572015
ERG gene rearrangements are common in prostatic small cell carcinomas
TL Lotan, NS Gupta, W Wang, A Toubaji, MC Haffner, A Chaux, JL Hicks, ...
Modern pathology 24 (6), 820-828, 2011
2292011
Disulfiram is a DNA demethylating agent and inhibits prostate cancer cell growth
J Lin, MC Haffner, Y Zhang, BH Lee, WN Brennen, J Britton, SK Kachhap, ...
The Prostate 71 (4), 333-343, 2011
2132011
Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma
BA Orr, MC Haffner, WG Nelson, S Yegnasubramanian, CG Eberhart
PloS one 7 (7), e41036, 2012
1952012
Comprehensive evaluation of programmed death-ligand 1 expression in primary and metastatic prostate cancer
MC Haffner, G Guner, D Taheri, GJ Netto, DN Palsgrove, Q Zheng, ...
The American journal of pathology 188 (6), 1478-1485, 2018
1462018
Ipilimumab plus nivolumab and DNA-repair defects in AR-V7-expressing metastatic prostate cancer
K Boudadi, DL Suzman, V Anagnostou, W Fu, B Luber, H Wang, ...
Oncotarget 9 (47), 28561, 2018
1442018
Correlation of B7-H3 with androgen receptor, immune pathways and poor outcome in prostate cancer: an expression-based analysis
B Benzon, SG Zhao, MC Haffner, M Takhar, N Erho, K Yousefi, P Hurley, ...
Prostate cancer and prostatic diseases 20 (1), 28-35, 2017
1362017
Transcription-induced DNA double strand breaks: both oncogenic force and potential therapeutic target?
MC Haffner, AM De Marzo, AK Meeker, WG Nelson, ...
Clinical Cancer Research 17 (12), 3858-3864, 2011
1292011
Combination of methylated-DNA precipitation and methylation-sensitive restriction enzymes (COMPARE-MS) for the rapid, sensitive and quantitative detection of DNA methylation
S Yegnasubramanian, X Lin, MC Haffner, AM DeMarzo, WG Nelson
Nucleic acids research 34 (3), e19-e19, 2006
1252006
Genome-wide comparison of the transcriptomes of highly enriched normal and chronic myeloid leukemia stem and progenitor cell populations
JM Gerber, JL Gucwa, D Esopi, M Gurel, MC Haffner, M Vala, WG Nelson, ...
Oncotarget 4 (5), 715, 2013
1192013
The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma
A Hector, EA Montgomery, C Karikari, MI Canto, KB Dunbar, JS Wang, ...
Cancer biology & therapy 10 (10), 1009-1018, 2010
1102010
Molecular evidence that invasive adenocarcinoma can mimic prostatic intraepithelial neoplasia (PIN) and intraductal carcinoma through retrograde glandular colonization
MC Haffner, C Weier, MM Xu, A Vaghasia, B Gürel, B Gümüşkaya, ...
The Journal of pathology 238 (1), 31-41, 2016
1022016
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