Follow
Radu Suciu
Title
Cited by
Cited by
Year
Chemical proteomics identifies druggable vulnerabilities in a genetically defined cancer
L Bar-Peled, EK Kemper, RM Suciu, EV Vinogradova, KM Backus, ...
Cell 171 (3), 696-709. e23, 2017
2212017
An activity-guided map of electrophile-cysteine interactions in primary human T cells
EV Vinogradova, X Zhang, D Remillard, DC Lazar, RM Suciu, Y Wang, ...
Cell 182 (4), 1009-1026. e29, 2020
2182020
Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium
N Pentinmikko, S Iqbal, M Mana, S Andersson, AB Cognetta, RM Suciu, ...
Nature 571 (7765), 398-402, 2019
1962019
A proteome-wide atlas of lysine-reactive chemistry
ME Abbasov, ME Kavanagh, TA Ichu, MR Lazear, Y Tao, VM Crowley, ...
Nature Chemistry 13 (11), 1081-1092, 2021
1212021
A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells
I Chefetz, E Grimley, K Yang, L Hong, EV Vinogradova, R Suciu, ...
Cell Reports 26 (11), 3061-3075. e6, 2019
1182019
Chemical Proteomic Profiling of Human Methyltransferases
BD Horning, RM Suciu, DA Ghadiri, OA Ulanovskaya, ML Matthews, ...
Journal of the American Chemical Society, 2016
892016
2-Sulfonylpyridines as Tunable, Cysteine-Reactive Electrophiles
C Zambaldo, EV Vinogradova, X Qi, J Iaconelli, RM Suciu, M Koh, ...
Journal of the American Chemical Society 142 (19), 8972-8979, 2020
732020
Direct Access to Versatile Electrophiles via Catalytic Oxidative Cyanation of Alkenes
DW Gao, EV Vinogradova, SK Nimmagadda, JM Medina, Y Xiao, ...
Journal of the American Chemical Society, 2018
662018
Dimethyl Fumarate Disrupts Human Innate Immune Signaling by Targeting the IRAK4–MyD88 Complex
BW Zaro, EV Vinogradova, DC Lazar, MM Blewett, RM Suciu, J Takaya, ...
The Journal of Immunology 202 (9), 2737-2746, 2019
552019
ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth
JR Remsberg, RM Suciu, NA Zambetti, TW Hanigan, AJ Firestone, ...
Nature Chemical Biology, 1-9, 2021
512021
Single-Cell Profiling and SCOPE-Seq Reveal Lineage Dynamics of Adult Ventricular-Subventricular Zone Neurogenesis and NOTUM as a Key Regulator
D Mizrak, NS Bayin, J Yuan, Z Liu, RM Suciu, MJ Niphakis, N Ngo, ...
Cell Reports 31 (12), 107805, 2020
482020
Selective Irreversible Inhibitors of the Wnt-Deacylating Enzyme NOTUM Developed by Activity-Based Protein Profiling
RM Suciu, AB Cognetta III, ZE Potter, BF Cravatt
ACS Medicinal Chemistry Letters, 2018
442018
The proteome‐wide potential for reversible covalency at cysteine
K Senkane, EV Vinogradova, RM Suciu, VM Crowley, BW Zaro, ...
Angewandte Chemie 131 (33), 11507-11511, 2019
432019
Activity-Based Hydrazine Probes for Protein Profiling of Electrophilic Functionality in Therapeutic Targets
Z Lin, X Wang, KA Bustin, K Shishikura, NR McKnight, L He, RM Suciu, ...
ACS central science 7 (9), 1524-1534, 2021
232021
Covalent inhibitors of nicotinamide N-methyltransferase (NNMT) provide evidence for target engagement challenges in situ
HY Lee, RM Suciu, BD Horning, EV Vinogradova, OA Ulanovskaya, ...
Bioorganic & Medicinal Chemistry Letters, 2018
212018
Genetic disruption of N-RasG12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice
NA Zambetti, AJ Firestone, JR Remsberg, BJ Huang, JC Wong, AM Long, ...
Blood 135 (20), 1772-1782, 2020
152020
A chemical proteomic probe for the mitochondrial pyruvate carrier complex
Y Yamashita, EV Vinogradova, X Zhang, RM Suciu, BF Cravatt
Angewandte Chemie 132 (10), 3924-3927, 2020
122020
Chemical proteomic identification of functional cysteines with atypical electrophile reactivities
K Litwin, VM Crowley, RM Suciu, DL Boger, BF Cravatt
Tetrahedron Letters 67, 152861, 2021
92021
GeneDig: a web application for accessing genomic and bioinformatics knowledge
RM Suciu, E Aydin, BE Chen
BMC Bioinformatics 16 (1), 67, 2015
62015
Chemical proteomic analysis of palmostatin beta-lactone analogs that affect N-Ras palmitoylation
RM Suciu, IK Luvaga, A Hazeen, C Weerasooriya, SK Richardson, ...
Bioorganic & Medicinal Chemistry Letters 53, 128414, 2021
32021
The system can't perform the operation now. Try again later.
Articles 1–20