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Roberto Pacifici
Roberto Pacifici
Verified email at emory.edu
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Year
Estrogen deficiency and bone loss: an inflammatory tale
MN Weitzmann, R Pacifici
The Journal of clinical investigation 116 (5), 1186-1194, 2006
11122006
Estrogen, cytokines, and pathogenesis of postmenopausal osteoporosis.
R Pacifici
Journal of bone and mineral research: the official journal of the American …, 1996
10131996
Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-α
S Cenci, MN Weitzmann, C Roggia, N Namba, D Novack, J Woodring, ...
The Journal of clinical investigation 106 (10), 1229-1237, 2000
8262000
Effect of surgical menopause and estrogen replacement on cytokine release from human blood mononuclear cells.
R Pacifici, C Brown, E Puscheck, E Friedrich, E Slatopolsky, D Maggio, ...
Proceedings of the National Academy of Sciences 88 (12), 5134-5138, 1991
7101991
Up-regulation of TNF-producing T cells in the bone marrow: A key mechanism by which estrogen deficiency induces bone loss in vivo
C Roggia, Y Gao, S Cenci, MN Weitzmann, G Toraldo, G Isaia, R Pacifici
Proceedings of the National Academy of Sciences 98 (24), 13960-13965, 2001
6382001
Marked decrease in plasma antioxidants in aged osteoporotic women: results of a cross-sectional study
D Maggio, M Barabani, M Pierandrei, MC Polidori, M Catani, P Mecocci, ...
The Journal of Clinical Endocrinology & Metabolism 88 (4), 1523-1527, 2003
6322003
IFN-γ stimulates osteoclast formation and bone loss in vivo via antigen-driven T cell activation
Y Gao, F Grassi, MR Ryan, M Terauchi, K Page, X Yang, MN Weitzmann, ...
The Journal of clinical investigation 117 (1), 122-132, 2007
5402007
Sex steroid deficiency–associated bone loss is microbiota dependent and prevented by probiotics
JY Li, B Chassaing, AM Tyagi, C Vaccaro, T Luo, J Adams, TM Darby, ...
The Journal of clinical investigation 126 (6), 2049-2063, 2016
5172016
Estrogen decreases osteoclast formation by down-regulating receptor activator of NF-κB ligand (RANKL)-induced JNK activation
S Srivastava, G Toraldo, MN Weitzmann, S Cenci, FP Ross, R Pacifici
Journal of Biological Chemistry 276 (12), 8836-8840, 2001
4932001
Ovarian steroid treatment blocks a postmenopausal increase in blood monocyte interleukin 1 release.
R Pacifici, L Rifas, R McCracken, I Vered, C McMurtry, LV Avioli, WA Peck
Proceedings of the National Academy of Sciences 86 (7), 2398-2402, 1989
4801989
Interleukin-1 receptor antagonist and tumor necrosis factor binding protein decrease osteoclast formation and bone resorption in ovariectomized mice.
R Kitazawa, RB Kimble, JL Vannice, VT Kung, R Pacifici
The Journal of clinical investigation 94 (6), 2397-2406, 1994
4171994
Simultaneous block of interleukin-1 and tumor necrosis factor is required to completely prevent bone loss in the early postovariectomy period
RB Kimble, AB Matayoshi, JL Vannice, VT Kung, C Williams, R Pacifici
Endocrinology 136 (7), 3054-3061, 1995
3851995
Spontaneous release of interleukin 1 from human blood monocytes reflects bone formation in idiopathic osteoporosis.
R Pacifici, L Rifas, S Teitelbaum, E Slatopolsky, R McCracken, M Bergfeld, ...
Proceedings of the National Academy of Sciences 84 (13), 4616-4620, 1987
3711987
Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-γ-induced class II transactivator
S Cenci, G Toraldo, MN Weitzmann, C Roggia, Y Gao, WP Qian, O Sierra, ...
Proceedings of the National Academy of Sciences 100 (18), 10405-10410, 2003
3652003
Estrogen deficiency increases the ability of stromal cells to support murine osteoclastogenesis via an interleukin-1and tumor necrosis factor-mediated stimulation of macrophage …
RB Kimble, S Srivastava, FP Ross, A Matayoshi, R Pacifici
Journal of Biological Chemistry 271 (46), 28890-28897, 1996
3381996
The microbial metabolite butyrate stimulates bone formation via T regulatory cell-mediated regulation of WNT10B expression
AM Tyagi, M Yu, TM Darby, C Vaccaro, JY Li, JA Owens, E Hsu, J Adams, ...
Immunity 49 (6), 1116-1131. e7, 2018
3332018
Cytokines, estrogen, and postmenopausal osteoporosis—the second decade
R Pacifici
Endocrinology 139 (6), 2659-2661, 1998
3311998
IL-7 induces bone loss in vivo by induction of receptor activator of nuclear factor κB ligand and tumor necrosis factor α from T cells
G Toraldo, C Roggia, WP Qian, R Pacifici, MN Weitzmann
Proceedings of the National Academy of Sciences 100 (1), 125-130, 2003
3182003
Interleukin-1 receptor antagonist decreases bone loss and bone resorption in ovariectomized rats.
RB Kimble, JL Vannice, DC Bloedow, RC Thompson, W Hopfer, VT Kung, ...
The Journal of clinical investigation 93 (5), 1959-1967, 1994
3161994
Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun and JunD
S Srivastava, MN Weitzmann, S Cenci, FP Ross, S Adler, R Pacifici
The Journal of clinical investigation 104 (4), 503-513, 1999
3131999
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