| Structure and regulation of soluble guanylate cyclase ER Derbyshire, MA Marletta Annual review of biochemistry 81, 533-559, 2012 | 531 | 2012 |
| Nitric oxide signaling: no longer simply on or off SPL Cary, JA Winger, ER Derbyshire, MA Marletta Trends in biochemical sciences 31 (4), 231-239, 2006 | 284 | 2006 |
| Diversity-oriented synthesis yields novel multistage antimalarial inhibitors N Kato, E Comer, T Sakata-Kato, A Sharma, M Sharma, M Maetani, ... Nature 538 (7625), 344-349, 2016 | 250 | 2016 |
| Liver-stage malaria parasites vulnerable to diverse chemical scaffolds ER Derbyshire, M Prudêncio, MM Mota, J Clardy Proceedings of the National Academy of Sciences 109 (22), 8511-8516, 2012 | 163 | 2012 |
| A nitric oxide/cysteine interaction mediates the activation of soluble guanylate cyclase NB Fernhoff, ER Derbyshire, MA Marletta Proceedings of the National Academy of Sciences 106 (51), 21602-21607, 2009 | 159 | 2009 |
| Biochemistry of soluble guanylate cyclase ER Derbyshire, MA Marletta cGMP: Generators, Effectors and Therapeutic Implications, 17-31, 2009 | 159 | 2009 |
| Takinib, a selective TAK1 inhibitor, broadens the therapeutic efficacy of TNF-α inhibition for cancer and autoimmune disease J Totzke, D Gurbani, R Raphemot, PF Hughes, K Bodoor, DA Carlson, ... Cell chemical biology 24 (8), 1029-1039. e7, 2017 | 129 | 2017 |
| Antibiotic and Antimalarial Quinones from Fungus-Growing Ant-Associated Pseudonocardia sp. G Carr, ER Derbyshire, E Caldera, CR Currie, J Clardy Journal of natural products 75 (10), 1806-1809, 2012 | 112 | 2012 |
| The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase JA Winger, ER Derbyshire, MH Lamers, MA Marletta, J Kuriyan BMC Structural Biology 8, 1-11, 2008 | 111 | 2008 |
| The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs JD Herman, LR Pepper, JF Cortese, G Estiu, K Galinsky, V Zuzarte-Luis, ... Science translational medicine 7 (288), 288ra77-288ra77, 2015 | 99 | 2015 |
| Dissociation of nitric oxide from soluble guanylate cyclase and heme-nitric oxide/oxygen binding domain constructs JA Winger, ER Derbyshire, MA Marletta Journal of Biological Chemistry 282 (2), 897-907, 2007 | 81 | 2007 |
| The next opportunity in anti-malaria drug discovery: the liver stage ER Derbyshire, MM Mota, J Clardy PLoS pathogens 7 (9), e1002178, 2011 | 78 | 2011 |
| Heme-assisted S-nitrosation desensitizes ferric soluble guanylate cyclase to nitric oxide NB Fernhoff, ER Derbyshire, ES Underbakke, MA Marletta Journal of Biological Chemistry 287 (51), 43053-43062, 2012 | 70 | 2012 |
| Plasmodium parasite exploits host aquaporin-3 during liver stage malaria infection D Posfai, K Sylvester, A Reddy, JG Ganley, J Wirth, QE Cullen, T Dave, ... PLoS pathogens 14 (5), e1007057, 2018 | 68 | 2018 |
| Identification and validation of tetracyclic benzothiazepines as Plasmodium falciparum cytochrome bc1 inhibitors CK Dong, S Urgaonkar, JF Cortese, FJ Gamo, JF Garcia-Bustos, ... Chemistry & biology 18 (12), 1602-1610, 2011 | 58 | 2011 |
| Characterization of Plasmodium Liver Stage Inhibition by Halofuginone ER Derbyshire, R Mazitschek, J Clardy ChemMedChem 7 (5), 844-849, 2012 | 50 | 2012 |
| Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice S Bang, CR Donnelly, X Luo, M Toro-Moreno, X Tao, Z Wang, S Chandra, ... Nature communications 12 (1), 1704, 2021 | 49 | 2021 |
| Nucleotide regulation of soluble guanylate cyclase substrate specificity ER Derbyshire, NB Fernhoff, S Deng, MA Marletta Biochemistry 48 (31), 7519-7524, 2009 | 47 | 2009 |
| Plasmodium chaperonin TRiC/CCT identified as a target of the antihistamine clemastine using parallel chemoproteomic strategy KY Lu, B Quan, K Sylvester, T Srivastava, MC Fitzgerald, ER Derbyshire Proceedings of the National Academy of Sciences 117 (11), 5810-5817, 2020 | 46 | 2020 |
| Characterization of two different five-coordinate soluble guanylate cyclase ferrous–nitrosyl complexes ER Derbyshire, A Gunn, M Ibrahim, TG Spiro, RD Britt, MA Marletta Biochemistry 47 (12), 3892-3899, 2008 | 45 | 2008 |
