Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance L Yang, P Li, S Fu, ES Calay, GS Hotamisligil Cell metabolism 11 (6), 467-478, 2010 | 1367 | 2010 |
Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity S Fu, L Yang, P Li, O Hofmann, L Dicker, W Hide, X Lin, SM Watkins, ... Nature 473 (7348), 528-531, 2011 | 1070 | 2011 |
Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss MF Gregor, L Yang, E Fabbrini, BS Mohammed, JC Eagon, ... Diabetes 58 (3), 693-700, 2009 | 607 | 2009 |
Tauroursodeoxycholic acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women M Kars, L Yang, MF Gregor, BS Mohammed, TA Pietka, BN Finck, ... Diabetes 59 (8), 1899-1905, 2010 | 446 | 2010 |
S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction L Yang, ES Calay, J Fan, A Arduini, RC Kunz, SP Gygi, A Yalcin, S Fu, ... Science 349 (6247), 500-506, 2015 | 225 | 2015 |
Autophagy in liver diseases: A review H Qian, X Chao, J Williams, S Fulte, T Li, L Yang, WX Ding Molecular aspects of medicine 82, 100973, 2021 | 163 | 2021 |
Long-term calorie restriction enhances cellular quality-control processes in human skeletal muscle L Yang, D Licastro, E Cava, N Veronese, F Spelta, W Rizza, B Bertozzi, ... Cell reports 14 (3), 422-428, 2016 | 151 | 2016 |
Multiple signals induce endoplasmic reticulum stress in both primary and immortalized chondrocytes resulting in loss of differentiation, impaired cell growth, and apoptosis L Yang, SG Carlson, D McBurney, WE Horton Journal of Biological Chemistry 280 (35), 31156-31165, 2005 | 124 | 2005 |
Cellular, molecular, and matrix changes in cartilage during aging and osteoarthritis WE Horton, P Bennion, L Yang Journal of Musculoskeletal and Neuronal Interactions 6 (4), 379, 2006 | 119 | 2006 |
IRE1α prevents hepatic steatosis by processing and promoting the degradation of select microRNAs JM Wang, Y Qiu, Z Yang, H Kim, Q Qian, Q Sun, C Zhang, L Yin, D Fang, ... Science signaling 11 (530), eaao4617, 2018 | 116 | 2018 |
The role of adipocyte XBP1 in metabolic regulation during lactation MF Gregor, ES Misch, L Yang, S Hummasti, KE Inouye, AH Lee, B Bierie, ... Cell reports 3 (5), 1430-1439, 2013 | 93 | 2013 |
The unfolded protein response regulates hepatic autophagy by sXBP1-mediated activation of TFEB Z Zhang, Q Qian, M Li, F Shao, WX Ding, VA Lira, SX Chen, SC Sebag, ... Autophagy 17 (8), 1841-1855, 2021 | 79 | 2021 |
S-Nitrosoglutathione Reductase Dysfunction Contributes to Obesity-Associated Hepatic Insulin Resistance via Regulating Autophagy Q Qian, Z Zhang, A Orwig, S Chen, WX Ding, Y Xu, RC Kunz, NRL Lind, ... Diabetes 67 (2), 193-207, 2018 | 63 | 2018 |
Stamp2 controls macrophage inflammation through nicotinamide adenine dinucleotide phosphate homeostasis and protects against atherosclerosis H ten Freyhaus, ES Calay, A Yalcin, SN Vallerie, L Yang, ZZ Calay, ... Cell metabolism 16 (1), 81-89, 2012 | 47 | 2012 |
A novel role for Bcl‐2 associated‐athanogene‐1 (Bag‐1) in regulation of the endoplasmic reticulum stress response in mammalian chondrocytes L Yang, D McBurney, SC Tang, SG Carlson, WE Horton Jr Journal of cellular biochemistry 102 (3), 786-800, 2007 | 42 | 2007 |
Stressing the brain, fattening the body L Yang, GS Hotamisligil Cell 135 (1), 20-22, 2008 | 32 | 2008 |
Hepatic lysosomal iNOS activity impairs autophagy in obesity Q Qian, Z Zhang, M Li, K Savage, D Cheng, AJ Rauckhorst, JA Ankrum, ... Cellular and molecular gastroenterology and hepatology 8 (1), 95-110, 2019 | 28 | 2019 |
A putative long noncoding RNA-encoded micropeptide maintains cellular homeostasis in pancreatic β cells M Li, F Shao, Q Qian, W Yu, Z Zhang, B Chen, D Su, Y Guo, AV Phan, ... Molecular Therapy-Nucleic Acids 26, 307-320, 2021 | 24 | 2021 |
Plasmid encoding microRNA-200c ameliorates periodontitis and systemic inflammation in obese mice T Krongbaramee, M Zhu, Q Qian, Z Zhang, S Eliason, Y Shu, F Qian, ... Molecular Therapy-Nucleic Acids 23, 1204-1216, 2021 | 20 | 2021 |
ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue SC Sebag, Z Zhang, Q Qian, M Li, Z Zhu, M Harata, W Li, LV Zingman, ... Cell reports 37 (7), 2021 | 13 | 2021 |