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Irene Santiago Tierno
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Increased cell stiffness contributes to complement‐mediated injury of choroidal endothelial cells in a monkey model of early age‐related macular degeneration
AP Cabrera, J Stoddard, I Santiago Tierno, N Matisioudis, M Agarwal, ...
The Journal of Pathology 257 (3), 314-326, 2022
72022
Subendothelial matrix stiffening by lysyl oxidase enhances RAGE-mediated retinal endothelial activation in diabetes
S Chandrakumar, I Santiago Tierno, M Agarwal, N Matisioudis, TS Kern, ...
Diabetes 72 (7), 973-985, 2023
52023
Mechanical regulation of retinal vascular inflammation and degeneration in diabetes
S Chandrakumar, I Santiago Tierno, M Agarwal, EM Lessieur, Y Du, ...
Diabetes 73 (2), 280-291, 2024
22024
Lysyl oxidase promotes neutrophil cytotoxicity towards retinal endothelial cells in diabetes
M Agarwal, S Chandrakumar, IS Tierno, A Chandra, EM Lessieur, ...
Investigative Ophthalmology & Visual Science 64 (8), 499-499, 2023
12023
Retinal vascular stiffening contributes to leukocyte-mediated endothelial apoptosis in diabetes
S Chandrakumar, IS Tierno, M Agarwal, E Lessieur, H Liu, TS Kern, ...
Investigative Ophthalmology & Visual Science 63 (7), 3595–A0050-3595–A0050, 2022
12022
Stiffness Measurement of Retinal Capillaries and Subendothelial Matrix using Atomic Force Microscopy
IS Tierno, M Agarwal, N Matisioudis, S Chandrakumar, K Ghosh
bioRxiv, 2024
2024
Stiffness Measurement of Retinal Capillaries and Subendothelial Matrix using Atomic Force Microscopy
I Santiago Tierno, M Agarwal, N Matisioudis, S Chandrakumar, K Ghosh
bioRxiv, 2024.02. 28.582372, 2024
2024
Lysyl oxidase mediates VEGF-and TNF-α-induced retinal endothelial activation
S Chandrakumar, M Agarwal, IS Tierno, K Ghosh
Investigative Ophthalmology & Visual Science 64 (8), 1817-1817, 2023
2023
Mechanical regulation of retinal vascular inflammation and degeneration in diabetic retinopathy
S Chandrakumar, IS Tierno, M Agarwal, EM Lessieur, Y Du, J Tang, ...
bioRxiv, 2022.12. 18.520943, 2022
2022
Lysyl oxidase-dependent subendothelial matrix stiffening promotes RAGE-mediated retinal endothelial activation in diabetes
S Chandrakumar, IS Tierno, M Agarwal, N Matisioudis, TS Kern, K Ghosh
bioRxiv, 2022.08. 31.505952, 2022
2022
Impaired neovascularization by choroidal endothelial cells from a monkey model of early age-related macular degeneration
IS Tierno, S Chandrakumar, M Agarwal, K Ghosh
Investigative Ophthalmology & Visual Science 63 (7), 278–F0323-278–F0323, 2022
2022
Role of cytoskeletal dynamics in neutrophil activation and cytotoxicity toward retinal endothelial cells in early diabetic retinopathy
M Agarwal, S Chandrakumar, IS Tierno, K Ghosh
Investigative Ophthalmology & Visual Science 63 (7), 1150-1150, 2022
2022
Cell Stiffening Contributes to Complement-mediated Injury of Choroidal Endothelial Cells in Early AMD
AP Cabrera, J Stoddard, IS Tierno, N Matisioudis, M Agarwal, L Renner, ...
bioRxiv, 2021.10. 06.463274, 2021
2021
Mechanical Control of AGE/RAGE Signaling in Retinal Vascular Inflammation
S Chandrakumar, IS Tierno, N Matisioudis, M Agarwal, K Ghosh
Investigative Ophthalmology & Visual Science 62 (8), 3028-3028, 2021
2021
ICAM-1-targeting Red Blood Cell-derived Nanoparticles for Local Suppression of Retinal Vascular Inflammation in Diabetes
K Ghosh, IS Tierno, V Tavva, N Palegar
Investigative Ophthalmology & Visual Science 61 (7), 291-291, 2020
2020
Lysyl oxidase-mediated subendothelial matrix stiffening contributes to advanced glycation end products-dependent retinal endothelial activation associated with diabetic retinopathy
S Chandrakumar, IS Tierno, K Ghosh
Investigative Ophthalmology & Visual Science 61 (7), 5409-5409, 2020
2020
Lysyl oxidase inhibition prevents inflammation-dependent retinal vascular atrophy in early diabetic retinopathy
IS Tierno, S Chandrakumar, H Liu, EM Lessieur, TS Kern, K Ghosh
Investigative Ophthalmology & Visual Science 61 (7), 1880-1880, 2020
2020
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